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Abstracts tagged "osteolysis"

  • Abstract Number: 1984 • ACR/ARP Annual Meeting 2019

    Alendronate-CGS21680 Conjugates Prevent Bone Erosion in a Murine Osteolysis Model but Not in A2A KO Mice

    Ane LarraƱaga-Vera1, Kiran S Toti 2, Sarah Sussman 3, Eugene Warnick 4, Harsha Rao 4, Zhan-Guo Gao 4, Alexandra Gadiano 4, Aranzazu Mediero 5, Kenneth A. Jacobson 4 and Bruce Cronstein 6, 1NYU Langone Health, New York, NY, 2National Institutes of Health, Bethesda, MD, 3Augusta University, Augusta, 4National Institutes of Health, Bethesda, 5IIS-FUNDACION JIMENEZ DIAZ, Madrid, Spain, 6Department of Medicine, Division of Rheumatology NYUSoM, NYC

    Background/Purpose: Implant loosening due to loss of bone is the most common cause of total joint replacement revision surgeries. One of the main cause of…

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