Abstracts tagged "osteoclasts and transcriptional regulation"

Abstract Number: 1888 • ACR/ARHP Annual Meeting 2014
PU.1, Mitf, and Their Novel Co-Partner, Eomes, Set up a Transcription Factor Network That Is Critical for Osteoclast Differentiation
Heather Carey¹, Sankha Ghosh¹, Eason Hildreth III², Jennifer Cabrera¹, Dias Kurmashev¹, Wael N. Jarjour³, Ramiro Toribio², Sudarshana Sharma¹ and Michael Ostrowski¹, ¹Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, ²Veterinary Clinical Sciences, The Ohio State University, Columbus, OH, ³Dept of Rheumatology/Medicine, The Ohio State University Wexner Medical Center, Columbus, OH
Background/Purpose Osteoclasts are bone resorbing cells which differentiate from myeloid precursors. The crosstalk between osteoblasts and osteoclasts tightly regulates the dynamic and continuous process of…