Abstracts tagged "Osteoclastogenesis and transcriptional regulation"

Abstract Number: 360 • 2015 ACR/ARHP Annual Meeting
Massive Elimination of Multinucleated Osteoclasts By Eupatilin Is Due to Dual Inhibition of Transcription and Cytoskeletal Rearrangement
Myeung Su Lee¹, Ju-Young Kim², Chang-Hoon Lee³, Wan-Hee Yoo⁴, Won Seok Lee⁴, Myong-Joo Hong⁵ and Jaemin Oh², ¹Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ²Anatomy, Wonkwang University, Iksan, South Korea, ³Rheumatology, Department of Internal Medicine, School of medicine, Wonkwang university, Iksan, Chonbuk, South Korea, ⁴Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine, Jeonju, South Korea, ⁵Internal Medicine, Presbyterian Medical center, Jeonju, South Korea
Background/Purpose: Osteoporosis is an ageing-associated diseases requiring better therapeutic modality. Eupatilin is a major flavonoid from Artemisia. We aimed to evaluate the effects of eupatilin on…

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