osteoarthritis and tumor necrosis factor (TNF) Archives

Abstract Number: 3200 • ACR/ARHP Annual Meeting 2016
Immunoscintigraphic Detection Of Tumor Necrosis Factor By Radiolabeled Certolizumab Pegol in Patients with Erosive Hand Osteoarthritis in Relation to Disease Activity: A Proof of Concept Study
Ruth Wittoek¹, Philippe Carron², Bieke Lambert³, Paulien Meersseman¹, Gust Verbruggen¹, Filip van Den Bosch¹ and Dirk Elewaut⁴, ¹Rheumatology, Ghent University Hospital, Ghent, Belgium, ²Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ³Department of Nuclear Medicine Ghent University Hospital, Department of Nuclear Medicine Ghent University Hospital, Ghent, Belgium, ⁴Laboratory for Molecular Immunology and Inflammation, Department of Rheumatology, VIB, Ghent University and Ghent University Hospital, Ghent, Belgium
Background/Purpose: A recent randomized clinical trial in erosive osteoarthritis (OA) of finger joints with a TNF blocking agent, adalimumab, showed inhibition of radiographic progression…
Abstract Number: 81 • ACR/ARHP Annual Meeting 2014
Elevated Peripheral Blood Leukocyte Inflammatory Gene Expression in Radiographic Progressors with Symptomatic Knee Osteoarthritis: NYU and OAI Cohorts
Mukundan Attur¹, Alexander Statnikov², Svetlana Krasnokutsky Samuels¹, Virginia B. Kraus³, Joanne Jordan⁴, Braxton D. Mitchell⁵, Michelle Yau⁶, Jyoti Patel¹, Constantin F. Aliferis², Marc C. Hochberg⁷, Jonathan Samuels¹ and Steven B. Abramson⁸, ¹Rheumatology, NYU Langone Medical Center, New York, NY, ²Center for Health Informatics and Bioinformatics, NYU Langone Medical Center, New York, NY, ³Medicine/Rheumatology, Duke University Medical Center, Durham, NC, ⁴Thurston Arthritis Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵Departments of Medicine and Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, ⁶Epidemiology and Public Health, University of Maryland, Baltimore,, MD, ⁷Medicine, University of Maryland School of Medicine, Baltimore, MD, ⁸Dept of Rheumatology/Medicine, NYU Langone Medical Center, New York, NY
Background/Purpose: We and others have demonstrated low grade inflammation exists in OA joint tissues, where it may contribute to disease pathogenesis. In the current studies…

Abstracts tagged "osteoarthritis and tumor necrosis factor (TNF)"

Immunoscintigraphic Detection Of Tumor Necrosis Factor By Radiolabeled Certolizumab Pegol in Patients with Erosive Hand Osteoarthritis in Relation to Disease Activity: A Proof of Concept Study

Elevated Peripheral Blood Leukocyte Inflammatory Gene Expression in Radiographic Progressors with Symptomatic Knee Osteoarthritis: NYU and OAI Cohorts