ACR Meeting Abstracts

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Abstracts tagged "osteoarthritis and treatment"

  • Abstract Number: 442 • 2018 ACR/ARHP Annual Meeting

    Patient Factors Associated with Gaps in Osteoarthritis Care

    Lauren King1, Deborah A. Marshall2 and Gillian Hawker3, 1University of Toronto, Canada, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Community Health Sciences, University of Calgary, Calgary, AB, Canada, 3Women's College Research Institute/Women's College Hospital, Toronto, ON, Canada

    Background/Purpose: Exercise, weight loss, simple analgesic medications and joint injections are effective non-surgical treatments for knee osteoarthritis (OA) to reduce pain and improve function. While…
  • Abstract Number: 1055 • 2018 ACR/ARHP Annual Meeting

    The TLR-4 Inhibitor 6-Shogaol As a Treatment in Osteoarthritis Trough the Modulation of Chondrocyte Hypertrophy and Matrix Calcification

    Paula Gratal1, Aranzazu Mediero2, Ana Lamuedra1, Raquel Largo1 and Gabriel Herrero-Beaumont1, 1Bone and Joint Research Unit, IIS-Fundación Jiménez Díaz UAM, Madrid, Spain, 2Joint and Bone Research Unit, IIS-Fundación Jiménez Díaz UAM, Madrid, Spain

    Background/Purpose: Osteoarthritis (OA) is a complex joint disease characterized by a progressive loss of articular cartilage (AC) and synovial inflammation. The latest theories of OA…
  • Abstract Number: 1194 • 2017 ACR/ARHP Annual Meeting

    Are Bisphosphonates Efficacious in Knee Osteoarthritis? A Meta-Analysis of Randomized Controlled Trials

    Mikala C. Osani1, Elizaveta Vaysbrot1, Raveendhara R. Bannuru2, Mia-Cara Musetti1 and Timothy E. McAlindon1, 1Division of Rheumatology, Tufts Medical Center, Boston, MA, 2Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA

    Background/Purpose: One of the key aspects of osteoarthritis (OA) pathogenesis is subchondral bone remodeling.  Bisphosphonates have been touted as disease-modifying agents for OA due to…
  • Abstract Number: 315 • 2015 ACR/ARHP Annual Meeting

    Structural Effects of Sprifermin in Knee Osteoarthritis: A Post-Hoc Analysis on Cartilage and Non-Cartilaginous Tissue Alterations

    Frank Roemer1, Aida Aydemir2, Stefan Lohmander3, Michel Crema4, Monica D. Marra5, Norma Muurahainen2, Felix Eckstein6 and Ali Guermazi7, 1Radiology, Boston University School of Medicine, Boston, MA, 2EMD Serono, Billerica, MA, 3Lund University, Lund, Sweden, 4Department of Radiology, Boston University School of Medicine, Boston, MA, 5Department of Radiology, BUSM, Boston, MA, 6Paracelsus Med Univ, Chondrometrics GmbH, Salzburg, Austria, 7Boston University School of Medicine, Boston, MA

    Background/Purpose: A randomized, double-blind, placebo-controlled phase 1b clinical trial of sprifermin (rhFGF18) in knee OA assessed central medial tibio-femoral compartment cartilage thickness on quantitative MRI…
  • Abstract Number: 2251 • 2014 ACR/ARHP Annual Meeting

    Kneeling Disability Associated with the Treatment of Osteoarthritis: Analysis of a Copcord Study in Mexico

    Alexia Hernández-Cáceres1, Jacqueline Rodríguez-Amado1, Ingris Peláez-Ballestas2, David Vega-Morales3, Mario Garza-Elizondo1, Roberto Negrete-López1, Lorena Pérez-Barbosa1 and Janett Riega-Torres1, 1Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 2Departamento de Reumatología, Departamento de Reumatología Hospital General de México “Dr. Eduardo Liceaga”, Distrito Federal, Mexico, 3Rheumatology, Hospital Universitario UANL, Monterrey, Mexico

    Background/Purpose Osteoarthritis (OA) is the most prevalent rheumatic disease in Mexico. The core treatment, a combination of pharmacological and non-pharmacological modalities, is mainly performed in…
  • Abstract Number: 2240 • 2014 ACR/ARHP Annual Meeting

    An Exploratory 4-Week Study of a P2X3 Antagonist AF-219 in the Treatment of Patients with Osteoarthritis (OA) of the Knee

    Vibeke Strand1, Michael Kitt2, Alan Kivitz3, Anthony Ford2, Peter Butera2 and Bruce McCarthy2, 1Stanford University, Portola Valley, CA, 2Afferent Pharmaceuticals, Inc., San Mateo, CA, 3Altoona Center for Clinical Research, Duncansville, PA

    Background/Purpose Targeting P2X3 receptors that mediate the sensitizing effects of ATP released from inflamed and damaged tissues on the primary afferent neurons (PAN) of musculoskeletal…
  • Abstract Number: 1019 • 2014 ACR/ARHP Annual Meeting

    Targeting the Bone-Driven Metabolic OA Phenotype By a Novel Dual Amylin Calcitonin Receptor Agonist, KBP-056

    Ditte Reker, Sara Toftegaard Hjuler, Kim Andreassen, Morten Asser Karsdal, Kim Henriksen and Anne C. Bay-Jensen, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark

    Background/Purpose: Osteoarthritis (OA) may be segregated into different disease phenotypes based on disease drivers; cartilage damage, joint inflammation or subchondral bone remodelling. Each phenotype may…
  • Abstract Number: 2151 • 2013 ACR/ARHP Annual Meeting

    Synergistic Effect of Combining BioniCare® in an Unloading Brace for Osteoarthritis of the Knee

    Thomas Zizic1, David S. Hungerford2, Edmund J. MacLaughlin3, Craig Mines4, Shaili Deveshwar5, Theresa Lawrence Ford6, Cynthia Elliott6, John R. Principe7, Jack S. Tuber8 and Joy Schechtman9, 1Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Ortho Surgery, Johns Hopkins University, Baltimore, MD, 3The Johns Hopkins University School of Medicine, Cambridge, MD, 4East Side OrthoCare, Snellville, GA, 5Sports Medicine and Orthopedic Center, Greensboro, NC, 6North Georgia Rheumatology, Lawrenceville, GA, 7WellBeingMD, Palos Heights, IL, 8The Johns Hopkins University, Baltimore, Maryland, Baltimore, MD, 9SunValley Arthritis Center, Peoria, AZ

    Background/Purpose: The purpose of this study was to see if incorporating the BioniCare device into an unloading brace would produce more rapid improvement, greater compliance…
  • Abstract Number: 2140 • 2013 ACR/ARHP Annual Meeting

    Effects Of Intra-Articular Hyaluronic Acid Injections On Gait Pattern In Patients With Knee Osteoarthritis

    Bilal Uysal1, Aysegul Ketenci2, Sina Esmaeilzadeh2 and Dilsad Sindel2, 1Physical Medicine And Rehabilitation, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 2Physical Medicine and Rehabilitation, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: The aim of this study was to determine the effects of intra-articular hyaluronic acid (HA) injections on gait pattern of both injected and un-injected…
  • Abstract Number: 53 • 2013 ACR/ARHP Annual Meeting

    Adenosine A2A Receptor As a Potential New Therapeutic Target For The Prevention/Treatment Of Osteoarthritis

    Aranzazu Mediero1, Tuere Wilder2 and Bruce N. Cronstein3, 1Medicine, Division of Translational Medicine, NYU School of Medicine, New York, NY, 2Medicine, division of Translational Medicine, NYU School of Medicine, New York, NY, 3Internal Medicine, NYU School of Medicine, Division of Rheumatology, New York, NY

    Background/Purpose: Osteoarthritis, the most common type of arthritis in the United States, results from trauma and other mechanical factors as well as metabolic changes in…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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