Abstracts tagged "osteoarthritis and stress"

Abstract Number: 1008 • 2017 ACR/ARHP Annual Meeting
mtDNA Cybrids from OA Patients Are Less Efficient Using Glycolysis and Are More Susceptible to Apoptosis Under Stress Conditions
Mercedes Fernandez Moreno^1,2, Tamara Hermida-Gómez³, Andrea Dalamao-Fernandez⁴, M. Eugenia Vazquez Mosquera⁴, Estefanía Cortés-Pereira¹, Morena Scotece⁴, Sara Relaño-Fernandez⁵, Ignacio Rego-Pérez¹ and Francisco J Blanco⁶, ¹Servicio de Reumatología. Area Genomica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ²CIBER-BBM, Madrid, Spain, ³Rheumatology, INIBIC. Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. CIBER-BBN., A Coruña, Spain, ⁴Servicio de Reumatología. Area Genomica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A CORUÑA, Spain, ⁵Plataforma de Genómica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain
Background/Purpose: Previous studies have showed that chondrocytes from OA patients had mitochondrial alteration in comparison with healthy. However the role of mitochondria in the biological…

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