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Abstracts tagged "osteoarthritis and radiography"

  • Abstract Number: 203 • 2014 ACR/ARHP Annual Meeting

    Predictors of Radiographic Progression of Interphalangeal Finger Joints in Erosive Osteoarthritis: A Prospective Study

    Paulien Meersseman1, Celine Van De Vyver2, Gust Verbruggen1, Dirk Elewaut1 and Ruth Wittoek1, 1Rheumatology, Department of Rheumatology Ghent University Hospital, Ghent, Belgium, 2Department of Rheumatology Ghent University Hospital, Ghent, Belgium

    Background/Purpose Predictors of radiographic progression in erosive osteoarthritis (OA) are important in identifying patients with high risk of disease activity and consequently functional loss. Disease…
  • Abstract Number: 201 • 2014 ACR/ARHP Annual Meeting

    Measures of Hip Morphology Are Related to Development of Incident Radiographic Hip Osteoarthritis over 6 to 13 Year Follow-up: The Johnston County Osteoarthritis Project

    Amanda E. Nelson1, Jamie L. Stiller1, Xiaoyan A. Shi2, Kirsten M. Leyland3, Jordan B. Renner4, Todd A. Schwartz5, Nigel K. Arden3 and Joanne M. Jordan6, 1University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, 2SAS Institute, Inc, Cary, NC, 3NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, 4University of North Carolina Department of Radiology, Chapel Hill, NC, 5Biostatistics, University of North Carolina Gillings School of Global Public Health, Dept of Biostatistics, Chapel Hill, NC, 6Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC

    Background/Purpose: Alterations in hip morphology, such as femoroacetabular impingement, have been associated with incident hip OA and total hip replacement (THR), but have rarely been…
  • Abstract Number: 152 • 2013 ACR/ARHP Annual Meeting

    The Uncoupling mtDNA Haplogroup T Associates With Better Radiographic Progression Of Osteoarthritis. Data From The Osteoarthritis Initiative (OAI)

    Angel Soto-Hermida1, Ignacio Rego-Pérez2, Mercedes Fernández-Moreno1, Sonia Pértega-Díaz3, Juan Fernández-Tajes1, María Eugenia Vázquez-Mosquera1, Estefanía Cortés-Pereira1, Sara Relaño-Fernández1, Natividad Oreiro-Villar1, Carlos Fernández-López1 and Francisco J. Blanco1,4,5, 1INIBIC-Hospital Universitario A Coruña. Rheumatology Division. Genomic Group, A Coruña, Spain, 2Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 3Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, 4CIBER-BBN-ISCIII, Madrid, Spain, 5Proteo-Red/ISCIII, Madrid, Spain

    Background/Purpose: The Osteoarthritis Initiative (OAI) is a multicentre study focused on identifying and evaluating risk factors of knee osteoarthritis (OA). Previous studies carried out by…
  • Abstract Number: 1133 • 2013 ACR/ARHP Annual Meeting

    Sensitivity To Change Of a New Method Of Computer Measurement Of Hip Joint Space Width: Performance Of Location-Specific Measures Obtained At a 48 Month Interval

    Charles Ratzlaff1 and Jeffrey W. Duryea2, 1Harvard Medical School / Brigham and Women's Hospital, Boston, MA, 2Radiology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose : Responsive measures of radiographic joint space width (JSW) in hip osteoarthritis (OA) are a major requirement for the evaluation of treatment interventions. The…
  • Abstract Number: 1132 • 2013 ACR/ARHP Annual Meeting

    Sensitivity To Change Of Radiographic Fixed-Location and Magnetic Resonance Imaging-Based Cartilage Thickness Measures In The Lateral Compartment Of Knees With Radiographic Osteoarthritis – Data From The Osteoarthritis Initiative

    Wolfgang Wirth1, Jeffrey W. Duryea2, Michael C. Nevitt3, Robert J. Buck4, David Hunter5 and Felix Eckstein1, 1Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, 2Radiology, Brigham and Women's Hospital, Boston, MA, 3Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 4StatAnswers Consulting, Minneapolis, MN, 5Royal North Shore Hospital, St. Leonards, Australia

    Background/Purpose: Radiographic joint space width (JSW) is frequently employed to indirectly assess structural progression in the medial femorotibial compartment, but it is unclear whether assessment…
  • Abstract Number: 1131 • 2013 ACR/ARHP Annual Meeting

    Peri-Articular Fractal Signature Analysis and Bone Mineral Density Measure Different Aspects Of Bone: Cross-Sectional Data From The Osteoarthritis Initiative

    Jeffrey B. Driban1, Felix Liu2, Alina O'Brien3, Lori Lyn Price4, Grace H. Lo5, Michael C. Nevitt6, Charles Eaton7, Timothy E. McAlindon8 and John A. Lynch9, 1Rheumatology, Tufts Medical Center, Boston, MA, 2University of California at San Francisco, San Francisco, CA, 3Tufts Medical Center, Boston, MA, 4Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 5VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, 6Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, 7Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, 8Division of Rheumatology, Tufts Medical Center, Boston, MA, 9Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA

    Background/Purpose: Peri-articular fractal signature analysis (FSA) and bone mineral density (paBMD) are potentially cost-effective prognostic imaging markers for osteoarthritis (OA) progression. While we know that…
  • Abstract Number: 235 • 2013 ACR/ARHP Annual Meeting

    Meniscal Extrusion Is a Better Predictor Of Radiographic Osteoarthritis Change Over Ten Years Compared To Cartilage Volume Loss

    Louisa Chou1, Hussain Ijaz Khan1, Andrew McBride1, Dawn Aitken1, Changhai Ding2, Leigh Blizzard3, Jean-Pierre Pelletier4, Johanne martel-Pelletier4, Flavia Cicuttini5 and Graeme Jones2, 1Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, 2Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, 3Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 4Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, 5Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

    ·         Background/Purpose: Change in joint space narrowing (JSN) on radiographs is currently the gold standard for monitoring disease progression of knee osteoarthritis in clinical trials…
  • Abstract Number: 237 • 2013 ACR/ARHP Annual Meeting

    The Association Of Radiographic Disease With Lesions On MRI In Lateral Compartment Knee Osteoarthritis: The Osteoathritis Initiative

    Barton L. Wise1, Jingbo Niu2, Felix Liu3, John A. Lynch4, Yuqing Zhang5, Ali Guermazi6, David T. Felson5, C. Kent Kwoh7 and Nancy E. Lane1, 1Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3University of California at San Francisco, San Francisco, CA, 4Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, 5Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 6Boston University, Boston, MA, 7School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose:   Lateral compartment knee tibio-femoral radiographic osteoarthritis (ROA) is associated with pain and disability, and the epidemiology of this form of knee OA is…
  • Abstract Number: 239 • 2013 ACR/ARHP Annual Meeting

    A Family History Of Knee Joint Replacement Increases The Progression Of Knee Joint Radiographic Osteoarthritis and Cartilage Volume Loss Over Ten Years

    Hussain Ijaz Khan1, Dawn Aitken1, Louisa Chou1, Andrew McBride1, Changhai Ding2, Jean Pierre Pelletier3,4, Johanne M. Pelletier5, Leigh Blizzard6, Flavia Cicuttini7 and Graeme Jones2, 1Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, 2Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, 3Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, 4Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, 5Pharmacology, Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, 6Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, 7Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia

    Background/Purpose: Osteoarthritis (OA) is a disease of multifactorial origin with a modest but significant heritable effect for disease severity in the knee joint. The aim…
  • Abstract Number: L19 • 2013 ACR/ARHP Annual Meeting

    Kellgren-Lawrence Grade (KL) 0 Vs. KL 1 Knees Differ in Their MRI Predictors of Subsequent Radiographic Osteoarthritis

    C.Kent Kwoh1, Ali Guermazi2, Tomoko Fujii3, Robert M. Boudreau3, Michael Hannon4, Jason Grago4, David Hunter5, Felix Eckstein6 and Frank Roemer7, 1Department of Medicine, The University of Arizona Arthritis Center, Tucson, AZ, 2Radiology, Boston University School of Medicine, Boston, MA, 3Epidemiology, University of Pittsburgh, Pittsburgh, PA, 4Medicine, University of Pittsburgh, Pittsburgh, PA, 5University of Sydney, Sydney, Australia, 6Paracelsus Medical University, Salzburg, Austria, 7Klinikum Augsburg, Augsburg, Germany

    Background/Purpose: Kellgren-Lawrence grade (KL) 1, defined by a questionable osteophyte and/or doubtful joint space narrowing, is thought to be an intermediate stage from non-OA (i.e.,…
  • Abstract Number: 1110 • 2012 ACR/ARHP Annual Meeting

    Radiologic Progression in Hand Osteoarthritis (OA) Over 2.6 Years – Data From the Sekoia Trial

    Emmanuel Maheu1, Christian Cadet2 and Francis Berenbaum1, 1Rheumatology, AP-HP, St Antoine Hospital, Paris, France, 2Rheumatology, Paris, France

    Background/Purpose: Hand OA is a frequent polyarticular disease. Few is known with respect to its radiological progression over time, which in addition is difficult to…
  • Abstract Number: 1111 • 2012 ACR/ARHP Annual Meeting

    Erosive Evolution in Hand Osteoarthritis Is Associated with Incident Joint Tenderness Independent of MRI-Defined Bone Marrow Lesions and Synovitis

    Ida K. Haugen1, Barbara Slatkowsky-Christensen1, Pernille Boyesen1, Sølve Sesseng2, Désirée van der Heijde3 and Tore K. Kvien4, 1Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Radiology, Diakonhjemmet Hospital, Oslo, Norway, 3Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose:  Previous studies have shown no association between increased amount of radiographic hand osteoarthritis (OA) resulting in more hand pain/disabilities. In this longitudinal study, our…
  • Abstract Number: 1027 • 2012 ACR/ARHP Annual Meeting

    Frequency of MRI-Detected Hip Osteoarthritis Features in Persons with Chronic Hip Pain and the Diagnostic Performance of Radiography Using MRI As the Reference

    Li Xu1, Daichi Hayashi1, Ali Guermazi2, David J. Hunter3, Anton Winterstein4, Ling Li5, Klaus Bohndorf4 and Frank Roemer6, 1Department of Radiology, Boston University School of Medicine, Boston, MA, 2Boston University, Boston, MA, 3Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 4Department of Radiology, Klinikum Augsburg, Augsburg, Germany, 5Division of Research, New England Baptist Hospital, Boston, MA, 6Klinikum Augsburg, Augsburg, Germany

    Background/Purpose: Conventional radiography has been the standard imaging tool to diagnose and grade the severity of hip OA. However, radiography cannot visualize the bone marrow,…
  • Abstract Number: 1030 • 2012 ACR/ARHP Annual Meeting

    Frequency and Fluctuation of Susceptibility Artifacts in the Tibio-Femoral Joint Space in Painful Knees On 3T MRI and Association with Meniscal Tears, Radiographic Joint Space Narrowing and Calcifications

    Daichi Hayashi1, Mohamed Jarraya1, Ali Guermazi2, C. Kent Kwoh3, Michael J. Hannon4, Carolyn E. Moore5, John M. Jakicic6, Stephanie M. Green7 and Frank Roemer8, 1Department of Radiology, Boston University School of Medicine, Boston, MA, 2Boston University, Boston, MA, 3Rheum & Clinical Immunology, Univ of Pittsburgh, Pittsburgh, PA, 4Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, 5Department of Nutrition and Food Science, Texas Women's University, Houston, TX, 6University of Pittsburgh, PA, 7Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, 8Klinikum Augsburg, Augsburg, Germany

    Background/Purpose: Linear or punctate hypointensities are commonly seen on gradient echo (GRE) sequences in the tibiofemoral joint (TFJ) space of osteoarthritic joints. These magnetic susceptibility…
  • Abstract Number: 1034 • 2012 ACR/ARHP Annual Meeting

    Changing Osteoarthritis Treatment Assessment Paradigms: Subchondral Bone Is a More Responsive Measure of Progression Than the Current Radiographic Standard

    Michael A. Bowes1, Christopher B. Wolstenholme1, Devan Hopkinson1, Graham R. Vincent1 and Philip G. Conaghan2, 1Imorphics Ltd, Manchester, United Kingdom, 2University of Leeds, Leeds, United Kingdom

    Background/Purpose: Radiographic joint space width (JSW) assessment, a surrogate for cartilage assessment, is the standard for structure modification trials of osteoarthritis (OA). However the subchondral…
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