Abstracts tagged "osteoarthritis and radiography"

Abstract Number: 203 • 2014 ACR/ARHP Annual Meeting
Predictors of Radiographic Progression of Interphalangeal Finger Joints in Erosive Osteoarthritis: A Prospective Study
Paulien Meersseman¹, Celine Van De Vyver², Gust Verbruggen¹, Dirk Elewaut¹ and Ruth Wittoek¹, ¹Rheumatology, Department of Rheumatology Ghent University Hospital, Ghent, Belgium, ²Department of Rheumatology Ghent University Hospital, Ghent, Belgium
Background/Purpose Predictors of radiographic progression in erosive osteoarthritis (OA) are important in identifying patients with high risk of disease activity and consequently functional loss. Disease…
Abstract Number: 201 • 2014 ACR/ARHP Annual Meeting
Measures of Hip Morphology Are Related to Development of Incident Radiographic Hip Osteoarthritis over 6 to 13 Year Follow-up: The Johnston County Osteoarthritis Project
Amanda E. Nelson¹, Jamie L. Stiller¹, Xiaoyan A. Shi², Kirsten M. Leyland³, Jordan B. Renner⁴, Todd A. Schwartz⁵, Nigel K. Arden³ and Joanne M. Jordan⁶, ¹University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, ²SAS Institute, Inc, Cary, NC, ³NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, ⁴University of North Carolina Department of Radiology, Chapel Hill, NC, ⁵Biostatistics, University of North Carolina Gillings School of Global Public Health, Dept of Biostatistics, Chapel Hill, NC, ⁶Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Alterations in hip morphology, such as femoroacetabular impingement, have been associated with incident hip OA and total hip replacement (THR), but have rarely been…
Abstract Number: 152 • 2013 ACR/ARHP Annual Meeting
The Uncoupling mtDNA Haplogroup T Associates With Better Radiographic Progression Of Osteoarthritis. Data From The Osteoarthritis Initiative (OAI)
Angel Soto-Hermida¹, Ignacio Rego-Pérez², Mercedes Fernández-Moreno¹, Sonia Pértega-Díaz³, Juan Fernández-Tajes¹, María Eugenia Vázquez-Mosquera¹, Estefanía Cortés-Pereira¹, Sara Relaño-Fernández¹, Natividad Oreiro-Villar¹, Carlos Fernández-López¹ and Francisco J. Blanco^1,4,5, ¹INIBIC-Hospital Universitario A Coruña. Rheumatology Division. Genomic Group, A Coruña, Spain, ²Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ³Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ⁴CIBER-BBN-ISCIII, Madrid, Spain, ⁵Proteo-Red/ISCIII, Madrid, Spain
Background/Purpose: The Osteoarthritis Initiative (OAI) is a multicentre study focused on identifying and evaluating risk factors of knee osteoarthritis (OA). Previous studies carried out by…
Abstract Number: 1133 • 2013 ACR/ARHP Annual Meeting
Sensitivity To Change Of a New Method Of Computer Measurement Of Hip Joint Space Width: Performance Of Location-Specific Measures Obtained At a 48 Month Interval
Charles Ratzlaff¹ and Jeffrey W. Duryea², ¹Harvard Medical School / Brigham and Women's Hospital, Boston, MA, ²Radiology, Brigham and Women's Hospital, Boston, MA
Background/Purpose : Responsive measures of radiographic joint space width (JSW) in hip osteoarthritis (OA) are a major requirement for the evaluation of treatment interventions. The…
Abstract Number: 1132 • 2013 ACR/ARHP Annual Meeting
Sensitivity To Change Of Radiographic Fixed-Location and Magnetic Resonance Imaging-Based Cartilage Thickness Measures In The Lateral Compartment Of Knees With Radiographic Osteoarthritis – Data From The Osteoarthritis Initiative
Wolfgang Wirth¹, Jeffrey W. Duryea², Michael C. Nevitt³, Robert J. Buck⁴, David Hunter⁵ and Felix Eckstein¹, ¹Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ²Radiology, Brigham and Women's Hospital, Boston, MA, ³Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁴StatAnswers Consulting, Minneapolis, MN, ⁵Royal North Shore Hospital, St. Leonards, Australia
Background/Purpose: Radiographic joint space width (JSW) is frequently employed to indirectly assess structural progression in the medial femorotibial compartment, but it is unclear whether assessment…
Abstract Number: 1131 • 2013 ACR/ARHP Annual Meeting
Peri-Articular Fractal Signature Analysis and Bone Mineral Density Measure Different Aspects Of Bone: Cross-Sectional Data From The Osteoarthritis Initiative
Jeffrey B. Driban¹, Felix Liu², Alina O'Brien³, Lori Lyn Price⁴, Grace H. Lo⁵, Michael C. Nevitt⁶, Charles Eaton⁷, Timothy E. McAlindon⁸ and John A. Lynch⁹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²University of California at San Francisco, San Francisco, CA, ³Tufts Medical Center, Boston, MA, ⁴Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁵VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, ⁶Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁷Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, ⁸Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁹Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA
Background/Purpose: Peri-articular fractal signature analysis (FSA) and bone mineral density (paBMD) are potentially cost-effective prognostic imaging markers for osteoarthritis (OA) progression. While we know that…
Abstract Number: 235 • 2013 ACR/ARHP Annual Meeting
Meniscal Extrusion Is a Better Predictor Of Radiographic Osteoarthritis Change Over Ten Years Compared To Cartilage Volume Loss
Louisa Chou¹, Hussain Ijaz Khan¹, Andrew McBride¹, Dawn Aitken¹, Changhai Ding², Leigh Blizzard³, Jean-Pierre Pelletier⁴, Johanne martel-Pelletier⁴, Flavia Cicuttini⁵ and Graeme Jones², ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁴Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁵Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
· Background/Purpose: Change in joint space narrowing (JSN) on radiographs is currently the gold standard for monitoring disease progression of knee osteoarthritis in clinical trials…
Abstract Number: 237 • 2013 ACR/ARHP Annual Meeting
The Association Of Radiographic Disease With Lesions On MRI In Lateral Compartment Knee Osteoarthritis: The Osteoathritis Initiative
Barton L. Wise¹, Jingbo Niu², Felix Liu³, John A. Lynch⁴, Yuqing Zhang⁵, Ali Guermazi⁶, David T. Felson⁵, C. Kent Kwoh⁷ and Nancy E. Lane¹, ¹Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³University of California at San Francisco, San Francisco, CA, ⁴Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, ⁵Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁶Boston University, Boston, MA, ⁷School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Lateral compartment knee tibio-femoral radiographic osteoarthritis (ROA) is associated with pain and disability, and the epidemiology of this form of knee OA is…
Abstract Number: 239 • 2013 ACR/ARHP Annual Meeting
A Family History Of Knee Joint Replacement Increases The Progression Of Knee Joint Radiographic Osteoarthritis and Cartilage Volume Loss Over Ten Years
Hussain Ijaz Khan¹, Dawn Aitken¹, Louisa Chou¹, Andrew McBride¹, Changhai Ding², Jean Pierre Pelletier^3,4, Johanne M. Pelletier⁵, Leigh Blizzard⁶, Flavia Cicuttini⁷ and Graeme Jones², ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ⁴Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ⁵Pharmacology, Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ⁶Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁷Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
Background/Purpose: Osteoarthritis (OA) is a disease of multifactorial origin with a modest but significant heritable effect for disease severity in the knee joint. The aim…
Abstract Number: L19 • 2013 ACR/ARHP Annual Meeting
Kellgren-Lawrence Grade (KL) 0 Vs. KL 1 Knees Differ in Their MRI Predictors of Subsequent Radiographic Osteoarthritis
C.Kent Kwoh¹, Ali Guermazi², Tomoko Fujii³, Robert M. Boudreau³, Michael Hannon⁴, Jason Grago⁴, David Hunter⁵, Felix Eckstein⁶ and Frank Roemer⁷, ¹Department of Medicine, The University of Arizona Arthritis Center, Tucson, AZ, ²Radiology, Boston University School of Medicine, Boston, MA, ³Epidemiology, University of Pittsburgh, Pittsburgh, PA, ⁴Medicine, University of Pittsburgh, Pittsburgh, PA, ⁵University of Sydney, Sydney, Australia, ⁶Paracelsus Medical University, Salzburg, Austria, ⁷Klinikum Augsburg, Augsburg, Germany
Background/Purpose: Kellgren-Lawrence grade (KL) 1, defined by a questionable osteophyte and/or doubtful joint space narrowing, is thought to be an intermediate stage from non-OA (i.e.,…
Abstract Number: 1034 • 2012 ACR/ARHP Annual Meeting
Changing Osteoarthritis Treatment Assessment Paradigms: Subchondral Bone Is a More Responsive Measure of Progression Than the Current Radiographic Standard
Michael A. Bowes¹, Christopher B. Wolstenholme¹, Devan Hopkinson¹, Graham R. Vincent¹ and Philip G. Conaghan², ¹Imorphics Ltd, Manchester, United Kingdom, ²University of Leeds, Leeds, United Kingdom
Background/Purpose: Radiographic joint space width (JSW) assessment, a surrogate for cartilage assessment, is the standard for structure modification trials of osteoarthritis (OA). However the subchondral…
Abstract Number: 2534 • 2012 ACR/ARHP Annual Meeting
The Intensive Diet and Exercise for Arthritis Trial (IDEA): 18-Month Radiographic and MRI Outcomes
David J. Hunter¹, D. Beavers², Felix Eckstein³, Ali Guermazi⁴, Richard F. Loeser⁵, Barbara J. Nicklas⁶, Shannon Mihalko⁷, Gary D. Miller⁷, Mary Lyles⁸, Paul DeVita⁹, Claudine Legault¹⁰, J. Jeffery Carr¹¹, Jeff D. Williamson⁸ and Stephen P. Messier⁷, ¹Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ²Wake Forest University, Winston Salem, NC, ³Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria, ⁴Radiology, Boston University, Boston, MA, ⁵Section Of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, ⁶Center on Aging, Wake Forest University School of Medicine, Winston-Salem, NC, ⁷Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, ⁸Center on Aging, Wake Forest University School of Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, ⁹Department of Exercise and Sport Science, East Carolina University, Greenville, NC, ¹⁰Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, ¹¹Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC
Background/Purpose: Dietary induced weight loss is a proven non-pharmacologic intervention for osteoarthritis. Based upon current literature it is unclear if weight loss modifies structural progression.…
Abstract Number: 2468 • 2012 ACR/ARHP Annual Meeting
Incident Symptomatic Hip Osteoarthritis Is Associated with Differences in Hip Shape by Active Shape Modeling: The Johnston County Osteoarthritis Project
Amanda E. Nelson¹, Felix Liu², John A. Lynch³, Jordan B. Renner⁴, Todd A. Schwartz⁵, Nancy E. Lane⁶ and Joanne M. Jordan⁷, ¹University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, ²University of California at San Francisco, San Francisco, CA, ³Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, ⁴University of North Carolina Department of Radiology, Chapel Hill, NC, ⁵Biostatistics, University of North Carolina Gillings School of Global Public Health, Dept of Biostatistics, Chapel Hill, NC, ⁶Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ⁷Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: We investigated hip shape by active shape modeling (ASM) as a potential predictor of incident radiographic and symptomatic hip OA (rHOA and srHOA) in…
Abstract Number: 1122 • 2012 ACR/ARHP Annual Meeting
Identifying Radiographic Phenotypes of Early Knee Osteoarthritis Using Separate Quantitative Features Might Improve Patient Selection for More Targeted Treatment
Margot B. Kinds¹, Anne C. A. Marijnissen¹, Max A. Viergever², P.J. Emans³, J.W.J. Bijlsma¹, F.P.J.G. Lafeber¹ and P.M.J. Welsing⁴, ¹Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ²Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands, ³Orthopaedic Surgery, Maastricht University Medical Center, Maastricht, Netherlands, ⁴Rheumatology & Clinical Immunology, F02.127, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: Osteoarthritis (OA) is a degenerative joint disease characterized by pain and functional disability. The expression of OA varies significantly between individuals and over time,…
Abstract Number: 1105 • 2012 ACR/ARHP Annual Meeting
Lateral Tibio-Femoral Shift Related to Medial Knee Osteoarthritis
Roy H. Lidtke¹, Berna Goker², Abdurrahman Tufan³, Laura E. Thorp⁴ and Joel A. Block¹, ¹Section of Rheumatology, Rush University Medical Center, Chicago, IL, ²Internal Medicine-Rheumatology, Gazi University Medical School, Ankara, Turkey, ³Internal Medicine-Rheumatology, Gazi University School of Medicine, Ankara, Turkey, ⁴Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL
Background/Purpose: Medial knee osteoarthritis (MKOA) has been shown to be related to malalignment of the knee joint with several radiographs used to quantify the abnormality.…

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