ACR Meeting Abstracts

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Abstracts tagged "osteoarthritis and outcome measures"

  • Abstract Number: 1376 • 2018 ACR/ARHP Annual Meeting

    The Omeract-Oarsi Core Set of Outcome Domains to Measure in Clinical Trials for People with Hip and/or Knee Osteoarthritis

    Toby O Smith1, Gillian Hawker2, David J. Hunter3, Lyn March4, Beverly Shea5, Robin Christensen6, Francis Guillemin7, Caroline Terwee8, Paula Williamson9, Ewa M. Roos10, Richard Loeser11, Thomas J. Schnitzer12, Margreet Kloppenburg13, Tuhina Neogi14, Christoph Ladel15, Ulrike Kaiser16, Ali Mobasheri17, Nigel K Arden1, Marc C. Hochberg18, Alan Tennant19, Maarten de Wit20, Peter Tugwell21 and Philip G. Conaghan22, 1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, 2University of Toronto, Toronto, ON, Canada, 3University of Sydney, Sydney, Australia, 4Department of Rheumatology, Northern Clinical School, Institute of Bone and Joint Research, Kolling Institute, University of Sydney & Department of Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia, 5Bruyere Research Institute, Ottawa, ON, Canada, 6Department of Rheumatology, Musculoskeletal Statistics Unit: The Parker Institute, Bispebjerg and Frederiksberg Hospital, & Department of Rheumatology, Odense University Hospital, Copenhagen, Denmark, 7University of Lorraine, Nancy, France, Nancy, France, 8Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 9University of Liverpool, Liverpool, United Kingdom, 10Inst Sports and Biomechanics, University of Southern Denmark, Odense, Denmark, 11Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 12Northwestern University, Chicago, IL, 13Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands, 14Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 15Merck KGaA, Darmstadt, Germany, 16Universitätsklinikum Carl Gustav Carus Dresden, Dresden, Germany, 17Rheumatology, School of Veterinary Medicine, University of Surrey, Guildford, United Kingdom, 18University of Maryland School of Medicine, Baltimore, MD, 19Swiss Paraplegic Research, Nottwil, Switzerland, 20EULAR standing committee of PARE, Zurich, Switzerland, 21Center For Global Health, Institute of Population Hlth, Ottawa, ON, Canada, 22Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and National Institute for Health Research (NIHR) Leeds Biomedical Research Centre, Leeds, United Kingdom, Leeds, United Kingdom

    Background/Purpose: It has been over 20 years since the OMERACT core outcome set (COS) to measure in clinical trials with people who have hip and/or…
  • Abstract Number: 341 • 2015 ACR/ARHP Annual Meeting

    Construct Validity of Four Hand Mobility Measures in Hand Osteoarthritis (HOA)

    Féline Kroon1, Jessica Bijsterbosch1, Ingrid Meulenbelt2, Frits R. Rosendaal3, Désirée van der Heijde1 and Margreet Kloppenburg1,3, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Molecular Epidemiology, Leiden University Medical Center, Leiden, Netherlands, 3Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: The OMERACT HOA working group recently proposed ‘hand mobility' as an outcome measure in HOA trials, although no disease specific instruments are available yet.…
  • Abstract Number: 3018 • 2014 ACR/ARHP Annual Meeting

    Testing of a Newly Developed Computerized Animated Activity Questionnaire  for Assessing Activity Limitations in Patients with Hip and Knee Osteoarthritis

    Wilfred FH Peter1, Mick Loos2, Henrica de Vet3, Maarten Boers3, Jaap Harlaar4, Leo D. Roorda5, Rudolf Poolman6, Vanessa Scholtes6, Jan Bogaard7, Hilda Buitelaar1, Martijn P.M. Steultjens8, Ewa M. Roos9, Anne-Christine Rat10, Francis Guillemin11, Maria Grazia Benedetti12, Antonio Escobar Martinez13, Nina Østerås14 and Caroline Terwee3, 1Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 2Epidemiology and Biostatistics and the EMGO Institute for Health and Care research, VU University Medical Center, Amsterdam, Netherlands, 3Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 4Dep of Rehabilitation Medicine and MOVE research institute, VU University Medical Center, Amsterdam, Netherlands, 5Amsterdam Rehabilitation Research Center | Reade, Amsterdam, the Netherlands, Amsterdam, Netherlands, 6Department of Orthopedics, Joint Research, Onze Lieve Vrouwe Gasthuis, Amsterdam, Netherlands, 7Dep of Epidemiology and Biostatistics and the EMGO Institute for Health and Care research, VU University Medical Center, Amsterdam, Netherlands, 8Institute for Applied Health Research and School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, Scotland, 9Inst Sports and Biomechanics, University of Southern Denmark, Odense, Denmark, 10University Paris Descartes, EA 4360 APEMAC, University of Lorraine, Nancy, France, 11INSERM, Centre d'Investigation Clinique - Epidémiologie Clinique (CIC-EC) CIE6, Nancy, France, 12Physical Medicine and Rehabilitation Unit, Istituto Ortopedico Rizzoli, Bologna, Italy, 13Health Service Research Network on Chronic Diseases (REDISSEC), Basurto University Hospital, Bilbao, Spain, 14Department of rheumatology, National Advisory Unit for rehabilitation in rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose Self-report questionnaires and performance-based tests correlate moderately in measuring activity limitations, indicating that they measure different aspects. Self-reports measure mainly how patients think they…
  • Abstract Number: 2249 • 2014 ACR/ARHP Annual Meeting

    Criteria for Clinically Important Worsening in Knee and Hip Osteoarthritis

    Elien A.M. Mahler1, Alfons A. den Broeder2, Vincent J.J.F. Busch3, Johannes W.J. Bijlsma4 and Els van den Ende1, 1Department of Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 2Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, 3Orthopedics, Sint Maartenskliniek, Nijmegen, Netherlands, 4Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands

    Background/Purpose Clinically important worsening in OA has not been well defined. Validated worsening criteria are important for research but also clinical practice to make informed…
  • Abstract Number: 1137 • 2012 ACR/ARHP Annual Meeting

    Clinimetric Properties of a New Outcome Measure:the Hand-Osteoarthritis Aesthetic Damage Index

    N. Bellamy and Joan Hendrikz, Conrod, The University of Queensland, Herston, Queensland, Australia

    Background/Purpose: The 2006 OARSI Guidelines for hand OA clinical trials, recognised the potential value of an aesthetic damage assessment, but acknowledged the absence of any…
  • Abstract Number: 239 • 2012 ACR/ARHP Annual Meeting

    Knee Osteoarthritis Symptom Assessments That Combine Pain and Physical Activity Are Superior to Pain Alone

    Grace H. Lo1, Timothy E. McAlindon2, Gillian A. Hawker3, Jeffrey B. Driban4, Lori Lyn Price5, Jing Song6, Charles Eaton7, Marc C. Hochberg8, Rebecca D. Jackson9, C. Kent Kwoh10, Michael C. Nevitt11 and Dorothy D. Dunlop6, 1Michael E. DeBakey Veterans Affairs Medical Center / Baylor College of Medicine, Houston, TX, 2Division of Rheumatology, Tufts Medical Center, Boston, MA, 3Women's College Research Institute, University of Toronto, Toronto, ON, Canada, 4Rheumatology, Tufts Medical Center, Boston, MA, 5Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 6Northwestern University Feinberg School of Medicine, Chicago, IL, 7Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, 8Department of Medicine, University of Maryland, Baltimore, MD, 9Ohio State University, Columbus, OH, 10School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 11Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA

    Background/Purpose : Symptom assessment in knee osteoarthritis (OA) is challenging.  Knee pain does not always correlate well with radiographic severity, perhaps because people modify /…
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