Abstracts tagged "osteoarthritis and osteoblasts"

Abstract Number: 2134 • 2016 ACR/ARHP Annual Meeting
Bone Replaces Cartilage in Non-Weight Bearing Regions of Immobilized Knees
T Mark Campbell¹, Katherine Reilly², Odette Laneuville³, Hans Uhthoff⁴ and Guy Trudel⁵, ¹Physical Medicine and Rehabilitation, Elisabeth Bruyere Hospital, Ottawa, ON, Canada, ²Medicine, University of Ottawa, Ottawa, ON, Canada, ³Biology, University of Ottawa, Ottawa, ON, Canada, ⁴Surgery, The Ottawa Hospital, Ottawa, ON, Canada, ⁵Medicine, The Ottawa Hospital Rehabilitation Centre, Ottawa, ON, Canada
Bone Replaces Cartilage In Non-Weight Bearing Regions Of Immobilized KneesBackground/Purpose: Osteoarthritis causes pain, restricts joint range of motion, reduces function, is highly prevalent worldwide and…
Abstract Number: 13 • 2012 ACR/ARHP Annual Meeting
Visfatin/Nampt in Osteoarthritis: Sites of Production in Human Joints and Role of Its Enzymatic Activity
Marie-Charlotte Laiguillon¹, Carole Bougault¹, Xavier Houard², Marjolaine Gosset³, Geoffroy Nourissat⁴, Sabrina Priam¹, Zvezdana Mladenovic¹, Claire Jacques¹, Francis Berenbaum⁵ and Jeremie Sellam⁶, ¹Ur-4, Pierre et Marie Curie University Paris VI, Paris, France, ²Sorbonne Universités, UPMC Univ Paris 06, UMRS 938 and Inflammation-Immunopathology-Biotherapy Department (DHU i2B), Paris, France, ³EA 2496, Paris Descartes University, Montrouge, France, ⁴Orthopaedic Surgery and Traumatology, Pierre et Marie Curie University Paris VI, Paris, France, ⁵Rheumatology, AP-HP, St Antoine Hospital, Paris, France, ⁶Rheumatology, Hopital Saint-Antoine, Pierre et Marie Curie University Paris 6, AP-HP, 75012, France
Background/Purpose: The role of cytokines produced by obese-derived adipose tissue, namely adipokines, in the pathophysiology of osteoarthritis (OA) is now well established. We recently suggested…
Abstract Number: 890 • 2012 ACR/ARHP Annual Meeting
The Role of Adipocytokines in Osteophyte Formation in Osteoarthritis
Susann Junker¹, Grit Krumbholz¹, Klaus Frommer¹, Angela Lehr², Stefan Rehart³, Jürgen Steinmeyer⁴, Markus Rickert⁵, Georg A. Schett⁶, Ulf Müller-Ladner⁷ and Elena Neumann⁸, ¹Department of Internal Medicine and Rheumatology, Kerckhoff-Klinik, Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, ²Dept Orthopedics and Trauma Surgery, Markus-Hospital, Frankfurt, Germany, ³Orthopedics and Trauma Surgery, Markus-Hospital, Frankfurt, Germany, ⁴Dept of Orthopedics and Orthopedic Surgery, University Hospital Gießen and Marburg, Gießen, Germany, ⁵Dept of Orthopedics and Orthopedic Surgery, University Hospital Giessen and Marburg, Giessen, Germany, ⁶Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, ⁷Internal Medicine and Rheumatology, Justus-Liebig-University of Gießen, Kerckhoff-Klinik, Bad Nauheim, Germany, ⁸Department of Internal Medicine and Rheumatology, Justus-Liebig-University of Gießen, Kerckhoff-Klinik, Bad Nauheim, Germany
Background/Purpose: Obesity is an established risk factor in osteoarthritis (OA), but there is not much known about the interaction between bone formation and the so-called…