ACR Meeting Abstracts

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Abstracts tagged "opioids"

  • Abstract Number: 2553 • 2019 ACR/ARP Annual Meeting

    Prescription Opioid Use and Osteoporotic Fractures in Systemic Lupus Erythematosus: The Michigan Lupus Epidemiology & Surveillance (MILES) Cohort

    Emily Somers1, Sioban Harlow 1, Nina Zhou 1, Lu Wang 1, Kamil Barbour 2, Charles Helmick 3, Caroline Gordon 4, Deeba Minhas 1, Beth Wallace 1, Afton Hassett 1, Suzanna Zick 1, W. Joseph McCune 5 and Wendy Marder 1, 1University of Michigan, Ann Arbor, 2Centers for Disease Control and Prevention, Atlanta, 3Centers for Disease Control and Prevention, Division of Population Health, Atlanta, GA, 4University of Birmingham, Birmingham, United Kingdom, 5University of Michigan, Ann Arbor, MI

    Background/Purpose: We recently reported prescription opioid use in nearly one-third of systemic lupus erythematosus (SLE) patients in our population-based cohort. Data suggest that opioids may…
  • Abstract Number: 442 • 2018 ACR/ARHP Annual Meeting

    Patient Factors Associated with Gaps in Osteoarthritis Care

    Lauren King1, Deborah A. Marshall2 and Gillian Hawker3, 1University of Toronto, Canada, Department of Medicine, University of Toronto, Toronto, ON, Canada, 2Community Health Sciences, University of Calgary, Calgary, AB, Canada, 3Women's College Research Institute/Women's College Hospital, Toronto, ON, Canada

    Background/Purpose: Exercise, weight loss, simple analgesic medications and joint injections are effective non-surgical treatments for knee osteoarthritis (OA) to reduce pain and improve function. While…
  • Abstract Number: 1374 • 2018 ACR/ARHP Annual Meeting

    The Relationship between Loneliness and Osteoarthritis in US Adults from a Nationally Representative Survey

    Adeela Cheema1, Louise Hawkley2, Kristen Wroblewski3 and Kichul Ko4, 1Section of Geriatrics and Palliative Medicine, Department of Medicine, University of Chicago, Chicago, IL, 2NORC, University of Chicago, Chicago, IL, 3Department of Public Health Sciences, University of Chicago, Chicago, IL, 4Section of Rheumatology, Department of Medicine, University of Chicago, Chicago, IL

    Background/Purpose: Loneliness in adults is a growing phenomenon across the Western world. It is associated with increased mortality, depression, coronary heart disease and stroke. Moreover,…
  • Abstract Number: 1917 • 2018 ACR/ARHP Annual Meeting

    Physician Opioid Prescribing Patterns and Risk for Chronic Opioid Use Among Rheumatoid Arthritis Patients

    Yvonne C. Lee1, Bing Lu2, Hongshu Guan3, Jeffrey Greenberg4, Joel Kremer5 and Daniel Solomon6, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Rheumatology Immunology & Allergy, Brigham & Women's Hospital, Boston, MA, 3Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 4Corrona, LLC, Waltham, MA, 5Albany Medical College and The Center for Rheumatology, Albany, NY, 6Rheumatology, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Experts have implicated physician prescribing rates as a contributing factor to the opioid crisis. However, little is known about heterogeneity in these patterns and…
  • Abstract Number: 1919 • 2018 ACR/ARHP Annual Meeting

    Individual Short-Acting Opioids and the Risk of Opioid-Related Adverse Events in Adolescents

    Cecilia P. Chung1, S. Todd Callahan2, William Cooper2, William Dupont3, Katherine Murray1, Andrew Franklin4, Kathi Hall5, Judith A. Dudley5, C. Michael Stein1 and Wayne Ray5, 1Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 3Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 4Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, 5Health Policy, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose: Hydrocodone, codeine, oxycodone, and tramadol are frequently prescribed for moderate pain in adolescents. However, pharmacokinetic and pharmacodynamic differences between these short-acting opioids could affect…
  • Abstract Number: 440 • 2018 ACR/ARHP Annual Meeting

    Assessing Inappropriate Pain Management in Adults with Hip or Knee Osteoarthritis Treated with Different Opioid Intensity Regimens: Results from a Retrospective Database Analysis

    Nathaniel P. Katz1,2, Kavita Gandhi3, Wenhui Wei4, Ahong Huang5 and Li Wang6, 1President, Analgesic Solutions, Natick, MA, 2Tufts University School of Medicine, Boston, MA, 3Director, Global Health Economics and Outcomes Research, Teva Pharmaceutical Industries, Frazer, PA, 4Senior Director, Health Economics and Outcomes Research (HEOR), Regeneron Pharmaceuticals, Inc., Tarrytown, NY, 5Project Manager, STATinMED Research, Dallas, TX, 6Senior Director, Analytic Research, STATinMED Research, Dallas, TX

    Background/Purpose: Opioids are often prescribed for osteoarthritis (OA) pain management despite the need for balancing their risks and benefits. Since there are no standard criteria…
  • Abstract Number: 15L • 2017 ACR/ARHP Annual Meeting

    A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Titration-to-Effect Study of Orally Administered CR845 in Patients with Osteoarthritis of the Hip or Knee

    Sukirti Bagal, Catherine Munera, Patricia Brady and Joseph Stauffer, Cara Therapeutics, Stamford, CT

    Background/Purpose: CR845 is a selective kappa opioid receptor agonist with a peripheral mechanism of action. Here we report preliminary results from a Phase 2b study…
  • Abstract Number: 467 • 2017 ACR/ARHP Annual Meeting

    Smoking and Opioid Use Is Associated with Symptom Severity in Rheumatoid Arthritis

    Angela Karellis1,2, Emmanouil Rampakakis3, John S. Sampalis1,4, Martin Cohen5, Michael Starr5, Peter Ste-Marie6, Yoram Shir6, Mark Ware6 and MaryAnn FitzCharles6,7, 1JSS Medical Research, St-Laurent, QC, Canada, 2Department of Surgery, McGill University, Montreal, QC, Canada, 3JSS Medical Research, Montreal, QC, Canada, 4McGill University, Montreal, QC, Canada, 5Rheumatology, McGill University Health Centre, Montreal, QC, Canada, 6Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, 7Rheumatology, McGill University, Montreal, QC, Canada

    Smoking and Opioid Use Is Associated with Symptom Severity in Rheumatoid ArthritisBackground/Purpose: Cigarette smoking, both current and past, is a risk for incident rheumatoid arthritis…
  • Abstract Number: 856 • 2017 ACR/ARHP Annual Meeting

    Trends and Predictors of Chronic Opioid Use in Individuals with RA

    Yvonne C. Lee1, Joel Kremer2, Hongshu Guan3, Jeffrey D Greenberg4 and Daniel H. Solomon5, 1Rheumatology Immunology & Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2The Center for Rheumatology, Albany Medical College, Albany, NY, 3Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4NYU School of Medicine, New York, NY, 5Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: The opioid epidemic is a major public health concern, requiring urgent action. However, little is known about chronic opioid use among individuals with RA.…
  • Abstract Number: 2235 • 2017 ACR/ARHP Annual Meeting

    Factors Associated with Opioid Use in End-Stage Knee, Hip and Spine Osteoarthritis

    J. Denise Power1, Anthony V. Perruccio1, Rajiv Gandhi1, Christian Veillette1, J. Roderick Davey1, Stephen J. Lewis1, Khalid Syed1, Nizar Mahomed1 and Y. Raja Rampersaud2, 1Arthritis Program, Krembil Research Institute, University Health Network, Toronto, ON, Canada, 2Arthritis Program, Krembil Research Institute, University Health Network, Torotno, ON, Canada

    Background/Purpose: The use of prescription opioids has been under increasing scrutiny due to concerns about the potential for misuse, dependency and increased adverse events. The…
  • Abstract Number: 369 • 2016 ACR/ARHP Annual Meeting

    Opioid Prescriptions and Adverse Reactions in Children and Adolescents without Serious Diseases

    Cecilia P. Chung1, S. Todd Callahan2, William Cooper2, William Dupont3, Katherine Murray1, Kathi Hall4, Judith A. Dudley4, C. Michael Stein1 and Wayne Ray4, 1Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 3Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 4Health Policy, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose:  There is a well-described epidemic of deaths and hospitalizations related to opioid prescriptions in adults. However, little is known about opioid toxicity in children.…
  • Abstract Number: 995 • 2016 ACR/ARHP Annual Meeting

    Use of Opiate Diminished the Treatment Benefits of Motivational Interviewing for Fibromyalgia

    Dennis Ang1 and James Slaven2, 1Wake Forest University, Winston-Salem, NC, 2Biostatistics, Indiana University, Indianapolis, IN

    Background/Purpose: Opiate is not indicated in the treatment of fibromyalgia (FM). In fact, chronic use of opiate may even worsen the symptoms of fibromyalgia. There…
  • Abstract Number: 1982 • 2016 ACR/ARHP Annual Meeting

    Comparative Safety of Long-Acting Opioids for Non-Cancer Pain

    Cecilia P. Chung1, William Dupont2, Katherine Murray1, Kathi Hall3, C. Michael Stein1 and Wayne Ray3, 1Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 3Health Policy, Vanderbilt University Medical Center, Nashville, TN

    Background/Purpose:   Methods:   Results:   Conclusion:  
  • Abstract Number: 2186 • 2016 ACR/ARHP Annual Meeting

    Analgesic Use and Subsequent Risk of Falls in Participants with or at Risk of Knee Osteoarthritis

    Wei-Hsuan Lo-Ciganic1, Lysbeth Floden2, Erin L. Ashbeck3, Lili Zhou1 and C. Kent Kwoh3,4, 1Department of Pharmacy, Practice and Science, University of Arizona, College of Pharmacy, Tucson, AZ, 2Department Pharmacy, Practice and Science, University of Arizona, College of Pharmacy, Tucson, AZ, 3The University of Arizona Arthritis Center, Tucson, AZ, 4Rheumatology, University of Arizona, College of Medicine, Tucson, AZ

    Background/Purpose:  Analgesics including opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), antidepressants, and nutraceuticals are commonly used for pain relief in osteoarthritis (OA). Although it has been reported…
  • Abstract Number: 3003 • 2016 ACR/ARHP Annual Meeting

    Impact of Preoperative Opioid Use on Total Knee Arthroplasty Outcomes

    Savannah R. Smith1, Heidi Y. Yang2, Jamie E. Collins3, Jeffrey N. Katz4 and Elena Losina5, 1Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 2Orthopaedic and Arthritis Center for Outcomes Research, Brigham & Women's Hospital, Boston, MA, 3Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, 4Orthopaedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Orthopaedics, Brigham & Women's Hospital, Boston, MA

    Background/Purpose: Total knee arthroplasty (TKA) is an effective treatment for patients with end-stage knee osteoarthritis (OA); however, a growing body of evidence suggests that patients…
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