Abstracts tagged "obesity and osteoarthritis"

Abstract Number: 2533 • 2012 ACR/ARHP Annual Meeting
Weight Loss Is Associated with Structure Modification in Subjects with Radiographic Osteoarthritis of the Knee: Data From the Osteoarthritis Initiative
Marc C. Hochberg¹, Danuta I. Bujak², Jeffrey W. Duryea³, Knachelle Favors⁴ and John D. Sorkin⁴, ¹Department of Medicine, University of Maryland, Baltimore, MD, ²School of Medicine, University of Maryland, Baltimore, MD, ³Dept of Radiology, Brigham & Women, Boston, MA, ⁴VA Maryland Health Care System, Baltimore, MD
Background/Purpose: Obesity is a risk factor for the development and progression of knee osteoarthritis (OA) and weight loss is recommended as part of the management…
Abstract Number: 2538 • 2012 ACR/ARHP Annual Meeting
The Association of Fat Mass and Skeletal Muscle Mass with Clinical and Structural Knee Osteoarthritis: The Netherlands Epidemiology of Obesity Study
A. Willemien Visser¹, Marieke Loef¹, Martin den Heijer², Monique Reijnierse³, Frits R. Rosendaal² and Margreet Kloppenburg⁴, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands, ³Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Body mass index (BMI) is an important risk factor for knee osteoarthritis (OA), but BMI depends only upon height and weight and gives no…
Abstract Number: 2520 • 2012 ACR/ARHP Annual Meeting
Suppressor of Cytokine Signaling 3 Is Reduced in Obese Patients with Osteoarthritis and Regulates Leptin Responses in Chondrocytes
Anna Koskinen¹, Katriina Vuolteenaho¹, Riku Korhonen¹, Teemu Moilanen² and Eeva Moilanen¹, ¹The Immunopharmacology Research Group, University of Tampere School of Medicine and Tampere University Hospital, Tampere, Finland, ²Coxa Hospital for Joint Replacement, Tampere, Finland
Background/Purpose: Leptin is an adipokine whose concentrations in circulation are proportional to body fat stores and body mass index (BMI). Initially leptin was discovered to…
Abstract Number: 1097 • 2012 ACR/ARHP Annual Meeting
The Association of Fat Distribution and Clinically Defined Hand Osteoarthritis: The Netherlands Epidemiology of Obesity Study
A. Willemien Visser¹, Marieke Loef¹, Andreea Ioan-Fascinay¹, Martin den Heijer², Frits R. Rosendaal² and Margreet Kloppenburg³, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Obesity, assessed as body mass index (BMI) ≥ 30 kg/m2, is an important risk factor for osteoarthritis (OA). BMI depends only upon height and…
Abstract Number: 43 • 2012 ACR/ARHP Annual Meeting
Serum Amyloid A Level in Knee Osteoarthritis: Systemic and/or Local Production and Pro-Inflammatory Properties On Human Chondrocytes and Fibroblast-Like Synoviocytes
Dominique de Seny¹, Gaël Cobraiville², Sophie Neuville², Edith Charlier³, Biserka Relic¹, Florence Quesada Calvo³, Olivier Malaise³, Denis Malaise⁴, Laurence Lutteri⁵, Jean-Paul Chapelle⁵ and Michel G. Malaise¹, ¹Department of Rheumatology, GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, ²GIGA Research - University of Liège - CHU of Liège, Liège, Belgium, ³Department of Rheumatology, GIGA Research - University of Liège - CHU Liège, Liège, Belgium, ⁴University of Liège, Liège, Belgium, ⁵Medical Chemistry - CHU Liège, Liège, Belgium
Background/Purpose: Knee osteoarthritis (OA) is a disease frequently seen in obese patients, but the relationship might be more linked to fat than to weight. A-SAA…

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