OA and mesenchymal stem cells Archives

Abstract Number: 43 • ACR/ARHP Annual Meeting 2013
Overexpression Of Lamin A In Mesenchymal STEM CELLS Compromises Chondrogenesis and Enhances Adipogenesis
Jesús Mateos^1,2, Arancha Landeira^1,2, Alexandre De la Fuente^1,2, Iván Lesende-Rodríguez^1,3, Pablo Fernández-Pernas^1,3, Maria Carmen Arufe^2,3 and Francisco J. Blanco^1,2,4, ¹Rhematology Division, ProteoRed/ISCIII. INIBIC-Hospital A Coruña, 15006, A Coruña, Spain, ²CIBER-BBN, Zaragoza, Spain, ³Department of Medicine, Area of Anatomy and Human Embryology, University of A Coruña-INIBIC, A Coruña, Spain, ⁴Department of Medicine. University of Santiago de Compostela, Santiago de Compostela, Spain
Background/Purpose: Previous work by our group and others indicated that an accumulation of lamin A (LMNA) is associated with the osteoarthritis (OA) chondrocyte phenotype. Mutations…

Abstracts tagged "OA and mesenchymal stem cells"