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Abstracts tagged "Nuclear Medicine"

  • Abstract Number: 2613 • ACR Convergence 2025

    Ga-FAPI-04 PET/CT reveals increased fibroblast activation in synovial and enthesial tissues of psoriasis patients with arthralgia and predicts the development of psoriatic arthritis

    Giulia Corte1, Koray Tascilar2, armin Atzinger3, Alp Temiz2, Melek Yalcin Mutlu4, Rita Noversa de Sousa5, Maria Gabriella Raimondo6, Andreas Ramming7, Sara Bayat2, Michael Sticherling8, Torsten Kuwert9, Christian Schmidkonz9, Georg Schett10 and Filippo Fagni11, 1- Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, 2Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Germany, 3Department of Nuclear Medicine, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, 4Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, erlangen, 5Department of Internal Medicine 3, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, 6Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität (FAU) Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, 7Department of Internal Medicine 3, Rheumatology & Immunology, Friedrich-Alexander-University (FAU) & Universitätsklinikum Erlangen, Erlangen, Germany, 8Department of Dermatology, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, 9Department of Nuclear Medicine, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, Erlangen, 10Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany, 11Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Bayern, Germany

    Background/Purpose: 68Ga-FAPI-04 PET/CT reveals fibroblast activation in vivo and is increasingly used to assess rheumatic diseases, including inflammatory arthritides. (1,2) We previously demonstrated that the…
  • Abstract Number: 2610 • ACR Convergence 2025

    Imaging remission in aortitis associated with giant cell arteritis. Multicenter study with tocilizumab in monotherapy and combined therapy

    Adrian Martin-Gutierrez1, Javier Loricera2, Diana Prieto-Peña3, Vicente Aldasoro Cáceres4, Olga Maiz5, Eugenio de Miguel6, Eva Galíndez Agirregoikoa7, Ivan Ferraz Amaro8, Santos Castañeda9 and Ricardo Blanco10, 1Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Renedo de Piélagos, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 3Division of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain., Santander, Spain, 4Hospital Universitario de Navarra, Pamplona, Spain, 5Hospital Universitario de Donosti, Donostia, Spain, 6Hospital Universitario La Paz, Madrid, Spain, 7BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, 8Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 9Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, 10Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: Aortitis is a frequent and potential severe complication of giant cell arteritis (GCA)(GCA-aortitis). Tocilizumab (TCZ) was approved for the treatment of GCA, but its…
  • Abstract Number: 2470 • ACR Convergence 2025

    Impaired Myocardial Flow Reserve on 82-Rubidium Positron Emission Tomography in Patients with Systemic Sclerosis

    Attila Feher1, Morgan Emokpae2, Bindu Koyi2, Ibolya Csecs2, Baran Gunes3, Albert Sinusas2 and Monique Hinchcliff4, 1Yale University School of Medicine - New Haven, CT, New Haven, CT, 2Yale School of Medicine, New Haven, 3Yale University School of Medicine, Pompton Plains, NJ, 4Yale School of Medicine, Westport, CT

    Background/Purpose: Cardiovascular death ranks as the second leading cause of mortality related to systemic sclerosis (SSc), with coronary microvascular dysfunction (CMVD) likely contributing to this…
  • Abstract Number: 0511 • ACR Convergence 2025

    Submandibular Gland Ratio Stratifies Salivary Function and Reveals a Senescence Peak in Anti-SSA Positive Sjögren’s Syndrome

    Chiao-Feng Cheng1, Tseng-Cheng Chen2, Min-Shu Hsieh3, TING-YUAN LAN4, Jui-Hung Kao5, Yu Heng Lin6, Mei-Fang Cheng7, Yi-Chieh Chen8, Hsiao-Sang Chu9, Yi-Min Huang10, Cheng-Hsun Lu11, Ko-Jen Li11, Chieh-Yu Shen1 and Song-Chou Hsieh12, 1Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, Taipei, Taiwan (Republic of China), 2Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Taipei, Taiwan (Republic of China), 3Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 100225, Taiwan, Taipei, Taiwan (Republic of China), 4National Taiwan University Hospital Hsinchu Branch, Hsinchu City, Taiwan, 5Division of Allergy, Immunology and Rheumatology, Department of Internal Medicine, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan, Taipei, Taiwan (Republic of China), 6Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin, Taiwan, Taipei, Taiwan (Republic of China), 7Department of Nuclear Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan., Taipei, Taiwan (Republic of China), 8Department of Nuclear Medicine, National Taiwan University Hospital, Taipei, Taiwan., Taipei, Taiwan (Republic of China), 9Department of Ophthalmology, National Taiwan University Hospital, Taipei City, Taiwan., Taipei, Taiwan (Republic of China), 10Department of Internal Medicine, National Taiwan University Cancer Center, Taipei, Taiwan, Taipei, Taiwan (Republic of China), 11National Taiwan University Hospital, Taipei, Taiwan, 12National Taiwan Unuversity Hospital, Taipei City, Taiwan (Republic of China)

    Background/Purpose: In primary Sjögren’s syndrome (pSS), the histologic focus score reflects immune infiltration but does not capture irreversible glandular damage. We evaluated a submandibular gland…
  • Abstract Number: 1973 • ACR Convergence 2024

    Radioisotopic Synoviorthesis: Factors Associated with Good Response Evaluated by Ultrasound

    Camille Bourgeois1, Patricio Cardoso-Peñafiel2, Beatriz Villapún Burgoa3, Rebeca Perez Pascual3, Juan Carlos Nieto Gonzalez1, José María Álvaro-Gracia4, Enrique Calvo-Aranda2 and Juan Molina-Collada3, 1Hospital Universitario Gregorio Marañón, Madrid, Spain, 2Hospital Universitario Infanta Leonor, Madrid, Spain, 3Hospital General Universitario Gregorio Marañón, Madrid, Spain, 4Hospital Gregorio Marañón, Madrid, Spain

    Background/Purpose: Radioisotopic synoviorthesis (RS) is an intra-articular local therapy that uses radioisotopes for the treatment of chronic recurrent synovitis with inadequate response to conventional therapy.…
  • Abstract Number: 2648 • ACR Convergence 2024

    Diagnosis of Giant Cell Arteritis by 18F-FDG PET/CT in Patients on Glucocorticoid Therapy: Importance of Delayed Imaging

    Vicente Aldasoro1, Vicky Betech-Antar2, Santos Castañeda3, Eugenio De Miguel4, Juan José Rosales5 and Maria Jose García Velloso5, 1Hospital Universitario de Navarra, Pamplona, Spain, 2Clinica Universidad de Navarra, Pamplona, Spain, 3Hospital Universitario de la Princesa, Madrid, Spain, 4Hospital Universitario La Paz, Madrid, Spain, 5Clínica Universidad de Navarra, Pamplona, Spain

    Background/Purpose: The aim of this study is to analyse the diagnostic value of the delay images at 180 minutes in positron emission tomography (PET) performed in…
  • Abstract Number: 0218 • ACR Convergence 2024

    Incidental Findings on Whole Body 18F-FDG PET/CT in a Rheumatoid Arthritis Clinical Trial Population

    Christina Costeas1, Daniel Solomon2, Katherine Liao3, Jon Giles4, Joan Bathon5 and Jane Kang6, and the TARGET Trial Consortium, 1Columbia University Irving Medical Center, New York, NY, 2Brigham and Women's Hospital, Newton, MA, 3Brigham and Women's Hospital, Boston, MA, 4Cedars Sinai Medical Center, Los Angeles, CA, 5Columbia University, NEW YORK, NY, 6Columbia University Medical Center, New York, NY

    Background/Purpose: Performing whole body imaging inevitably reveals incidental findings in the majority of cases. A clinical trial was conducted to determine whether different treatment strategies…
  • Abstract Number: 0743 • ACR Convergence 2024

    Higher Baseline FDG Musculoskeletal Uptake at PET/CT Is Associated with a Higher Remission Rate in Polymyalgia Rheumatica: A Retrospective 3-year Observational Study

    Elvis Hysa1, Dario Camellino2, Cristina Bernini3, Paolo Vittoriano Clini4, Matteo Bauckneht5, silvia Morbelli6, Gianmario Sambuceti5, Emanuele Gotelli7, Alberto Sulli8, Maurizio Cutolo7 and Marco Amedeo Cimmino1, 1Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genoa, Italy, 2Division of Rheumatology, Local Health Trust 3, Genoa, Italy, 3Emergency Medicine Department, San Martino Polyclinic Hospital, Genoa, Italy,, Genoa, Italy, 4Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, 5Nuclear Medicine Unit and Department of Health Sciences, University of Genova, Genoa, Italy, Genoa, Italy, 6University of Torino, Torino, Italy, 7Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy, Genova, Italy, 8Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Genova, Italy

    Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are related inflammatory diseases characterized by increased musculoskeletal and vascular uptakes of 18-Fluorodeoxyglucose (18F-FDG) at positron…
  • Abstract Number: 0745 • ACR Convergence 2024

    Tocilizumab in Monotherapy vs. Combined in Aortitis Associated with Giant Cell Arteritis. Multicenter Open-label Study of 196 Patients

    Adrián Martín-Gutiérrez1, Javier Loricera2, Carmen Secada Gómez3, Javier Narvaez-García4, Olga Maíz Alonso5, Iñigo Hernández-Rodríguez6, Susana Romero Yuste7, Eugenio De Miguel8, Eva Galindez-Agirregoikoa9, ivan Ferraz-Amaro10, Julio Sánchez-Martín11, Patricia Moya Albarado12, Cristina Campos Fernández13, Fernando Lopez-Gutierrez14, Santos Castañeda15 and Ricardo Blanco-Alonso16, and the Tocilizumab in Giant Cell Arteritis Spanish Collaborative Group, 1Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 4Hospital Universitario de Bellvitge, Barcelona, Spain, 53Hospital Universitario de Donosti, San Sebastian, Spain, San Sebastian, Pais Vasco, Spain, 6Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 7Department of Rheumatology, University Hospital Complex of Pontevedra, Pontevedra, Spain, 8Hospital Universitario La Paz, Madrid, Spain, 9BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, 10Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, 11Hospital Universitario 12 de Octubre, Madrid, Spain, 12Hospital de San Pau, Barcelona, Spain, 13Escuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain, 14Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 15Hospital Universitario de la Princesa, Madrid, Spain, 16Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: Aortitis related to Giant Cell Arteritis (GCA-aortitis) is a frequent and potential severe complication. Tocilizumab (TCZ) was approved in GCA, but the efficacy in…
  • Abstract Number: 0767 • ACR Convergence 2024

    Comparing Large Vessel Uptake of 68Ga-HA-DOTATATE to 18F-FDG Using PET/CT Imaging in Patients with Active Giant Cell Arteritis

    Alison Clifford1, Jonathan Abele1, Ryan Hung1, Paolo Raggi1, Frank Wuest1, Jan Andersson1, Elaine Yacyshyn2, Eric Lenza1, Glen Jickling1 and Jan Willem Cohen Tervaert1, 1University of Alberta, Edmonton, Canada, 2University of Alberta, Edmonton, AB, Canada

    Background/Purpose: 18F-fluoro-deoxyglucose (FDG) is the current standard among radiotracers for PET/CT imaging of large vessel vasculitis (LVV) in giant cell arteritis (GCA), but its performance…
  • Abstract Number: 1620 • ACR Convergence 2024

    Unveiling of a New Molecular Imaging Biomarker? Vascular Adhesion Protein-1 and [68Ga]Ga-DOTA-Siglec-9 PET/CT in Detecting Giant Cell Arteritis Relapse

    Simon Petzinna1, Jim Küppers2, Benedikt Schemmer2, Anna Kernder3, Claus Juergen Bauer1, Pantelis Karakostas1, Denada Bruci3, Adina Morar3, Anja Winklbauer2, Markus Essler2 and Valentin S. Schäfer2, 1Clinic of Internal Medicine III, Department of Rheumatology, University Hospital of Bonn, Bonn, Germany, Bonn, Germany, 2University Hospital Bonn, Bonn, Germany, 3University Hospital Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany

    Background/Purpose: Vascular adhesion protein-1 (VAP-1) is a transmembrane adhesion molecule with oxidative deamination functionality, which is expressed in vascular smooth muscle cells and endothelial cells.…
  • Abstract Number: 1624 • ACR Convergence 2024

    Prognostic Value of Baseline 18F-FDG PET/CT Scan in Giant Cell Arteritis with Large Vessel Involvement

    Julio Sánchez-Martín1, Javier Loricera2, Isabel Martinez-Rodriguez3, ivan Ferraz-Amaro4, Nestor Martinez-Amador5, Remedios Quirce-Pisano5, Fernando Lopez-Gutierrez6 and Ricardo Blanco-Alonso7, 1Hospital Universitario 12 de Octubre, Madrid, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Nuclear Medicine, Hospital Universitario Marques de Valdecilla,IDIVAL, Santander, Cantabria, Spain, 4Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, 5Department of Nuclear Medicine, Hospital Universitario Marqués de Valdecilla, Molecular Imaging Group, IDIVAL, Santander., Santander, Spain, 6Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 7Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan has become a very useful diagnostic tool in patients with GCA with large vessel involvement. However,…
  • Abstract Number: 1054 • ACR Convergence 2023

    Immune Checkpoint Inhibitor Induced Polymyalgia Rheumatica Demonstrates a Similar Scintigraphic Appearance to Classical Polymyalgia Rheumatica on 18F-Fluorodeoxyglucose PET/CT

    David Liew1, Aurora Poon1, Christopher McMaster2, Russell Buchanan1, Victor Yang1, Andrew Scott1 and Claire Owen3, 1Austin Health, Heidelberg, Australia, 2Austin Health, Pascoe Vale South, Australia, 3Austin Health, Malvern East, Australia

    Background/Purpose: Of the rheumatic immune-related adverse events that follow immune checkpoint inhibitor (ICI) cancer immunotherapy, de novo PMR-like episodes without inflammatory arthritis (ICI-PMR) appear to…
  • Abstract Number: 1646 • ACR Convergence 2023

    The Real-World Experience of Combined Cranial and Large Vessel FDG-PET/CT in the Investigation of Giant Cell Arteritis

    Keren Port1, Ivan Ho Shon1, Sally Ayesa1, Rachel Langford1, Olivia Bennett1, Andrew Csillag1, Stacey Fredericks1, Luz Palacios-Derflingher2, Eva Wegner1 and Anthony Sammel1, 1The Prince of Wales Hospital, Sydney, Australia, 2University of New South Wales, Sydney, Australia

    Background/Purpose: GCA is a systemic medium-large vessel vasculitis (M-LVV) involving the cranial arteries, aorta and its major branches. Recent studies have shown that PET/CT including…
  • Abstract Number: 1890 • ACR Convergence 2023

    Use of Artificial Intelligence to Diagnose Polymyalgia Rheumatica on 18F-FDG Whole Body PET/CT in Patients with Atypical Clinical Features

    Emily Martin1, Christopher McMaster1, Saskia Rowson1, Victor Yang1, Aurora Poon1, Bonnia Liu1, Jessica Leung2, Andrew Scott1, David Liew1 and Claire Owen3, 1Austin Health, Heidelberg, Australia, 2Austin Health, Preston, Australia, 3Austin Health, Malvern East, Australia

    Background/Purpose: PET/CT is a highly sensitive and specific test for diagnosing PMR.(1) This study investigated the utility of 18F-FDG whole body PET/CT in patients presenting…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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