ACR Meeting Abstracts

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Abstracts tagged "Nuclear Medicine"

  • Abstract Number: 1973 • ACR Convergence 2024

    Radioisotopic Synoviorthesis: Factors Associated with Good Response Evaluated by Ultrasound

    Camille Bourgeois1, Patricio Cardoso-Peñafiel2, Beatriz Villapún Burgoa3, Rebeca Perez Pascual3, Juan Carlos Nieto Gonzalez1, José María Álvaro-Gracia4, Enrique Calvo-Aranda2 and Juan Molina-Collada3, 1Hospital Universitario Gregorio Marañón, Madrid, Spain, 2Hospital Universitario Infanta Leonor, Madrid, Spain, 3Hospital General Universitario Gregorio Marañón, Madrid, Spain, 4Hospital Gregorio Marañón, Madrid, Spain

    Background/Purpose: Radioisotopic synoviorthesis (RS) is an intra-articular local therapy that uses radioisotopes for the treatment of chronic recurrent synovitis with inadequate response to conventional therapy.…
  • Abstract Number: 2648 • ACR Convergence 2024

    Diagnosis of Giant Cell Arteritis by 18F-FDG PET/CT in Patients on Glucocorticoid Therapy: Importance of Delayed Imaging

    Vicente Aldasoro1, Vicky Betech-Antar2, Santos Castañeda3, Eugenio De Miguel4, Juan José Rosales5 and Maria Jose García Velloso5, 1Hospital Universitario de Navarra, Pamplona, Spain, 2Clinica Universidad de Navarra, Pamplona, Spain, 3Hospital Universitario de la Princesa, Madrid, Spain, 4Hospital Universitario La Paz, Madrid, Spain, 5Clínica Universidad de Navarra, Pamplona, Spain

    Background/Purpose: The aim of this study is to analyse the diagnostic value of the delay images at 180 minutes in positron emission tomography (PET) performed in…
  • Abstract Number: 0218 • ACR Convergence 2024

    Incidental Findings on Whole Body 18F-FDG PET/CT in a Rheumatoid Arthritis Clinical Trial Population

    Christina Costeas1, Daniel Solomon2, Katherine Liao3, Jon Giles4, Joan Bathon5 and Jane Kang6, and the TARGET Trial Consortium, 1Columbia University Irving Medical Center, New York, NY, 2Brigham and Women's Hospital, Newton, MA, 3Brigham and Women's Hospital, Boston, MA, 4Cedars Sinai Medical Center, Los Angeles, CA, 5Columbia University, NEW YORK, NY, 6Columbia University Medical Center, New York, NY

    Background/Purpose: Performing whole body imaging inevitably reveals incidental findings in the majority of cases. A clinical trial was conducted to determine whether different treatment strategies…
  • Abstract Number: 0743 • ACR Convergence 2024

    Higher Baseline FDG Musculoskeletal Uptake at PET/CT Is Associated with a Higher Remission Rate in Polymyalgia Rheumatica: A Retrospective 3-year Observational Study

    Elvis Hysa1, Dario Camellino2, Cristina Bernini3, Paolo Vittoriano Clini4, Matteo Bauckneht5, silvia Morbelli6, Gianmario Sambuceti5, Emanuele Gotelli7, Alberto Sulli8, Maurizio Cutolo7 and Marco Amedeo Cimmino1, 1Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genoa, Italy, 2Division of Rheumatology, Local Health Trust 3, Genoa, Italy, 3Emergency Medicine Department, San Martino Polyclinic Hospital, Genoa, Italy,, Genoa, Italy, 4Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, 5Nuclear Medicine Unit and Department of Health Sciences, University of Genova, Genoa, Italy, Genoa, Italy, 6University of Torino, Torino, Italy, 7Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy, Genova, Italy, 8Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Genova, Italy

    Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are related inflammatory diseases characterized by increased musculoskeletal and vascular uptakes of 18-Fluorodeoxyglucose (18F-FDG) at positron…
  • Abstract Number: 0745 • ACR Convergence 2024

    Tocilizumab in Monotherapy vs. Combined in Aortitis Associated with Giant Cell Arteritis. Multicenter Open-label Study of 196 Patients

    Adrián Martín-Gutiérrez1, Javier Loricera2, Carmen Secada Gómez3, Javier Narvaez-García4, Olga Maíz Alonso5, Iñigo Hernández-Rodríguez6, Susana Romero Yuste7, Eugenio De Miguel8, Eva Galindez-Agirregoikoa9, ivan Ferraz-Amaro10, Julio Sánchez-Martín11, Patricia Moya Albarado12, Cristina Campos Fernández13, Fernando Lopez-Gutierrez14, Santos Castañeda15 and Ricardo Blanco-Alonso16, and the Tocilizumab in Giant Cell Arteritis Spanish Collaborative Group, 1Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 4Hospital Universitario de Bellvitge, Barcelona, Spain, 53Hospital Universitario de Donosti, San Sebastian, Spain, San Sebastian, Pais Vasco, Spain, 6Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 7Department of Rheumatology, University Hospital Complex of Pontevedra, Pontevedra, Spain, 8Hospital Universitario La Paz, Madrid, Spain, 9BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, 10Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, 11Hospital Universitario 12 de Octubre, Madrid, Spain, 12Hospital de San Pau, Barcelona, Spain, 13Escuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain, 14Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 15Hospital Universitario de la Princesa, Madrid, Spain, 16Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: Aortitis related to Giant Cell Arteritis (GCA-aortitis) is a frequent and potential severe complication. Tocilizumab (TCZ) was approved in GCA, but the efficacy in…
  • Abstract Number: 0767 • ACR Convergence 2024

    Comparing Large Vessel Uptake of 68Ga-HA-DOTATATE to 18F-FDG Using PET/CT Imaging in Patients with Active Giant Cell Arteritis

    Alison Clifford1, Jonathan Abele1, Ryan Hung1, Paolo Raggi1, Frank Wuest1, Jan Andersson1, Elaine Yacyshyn2, Eric Lenza1, Glen Jickling1 and Jan Willem Cohen Tervaert1, 1University of Alberta, Edmonton, Canada, 2University of Alberta, Edmonton, AB, Canada

    Background/Purpose: 18F-fluoro-deoxyglucose (FDG) is the current standard among radiotracers for PET/CT imaging of large vessel vasculitis (LVV) in giant cell arteritis (GCA), but its performance…
  • Abstract Number: 1620 • ACR Convergence 2024

    Unveiling of a New Molecular Imaging Biomarker? Vascular Adhesion Protein-1 and [68Ga]Ga-DOTA-Siglec-9 PET/CT in Detecting Giant Cell Arteritis Relapse

    Simon Petzinna1, Jim Küppers2, Benedikt Schemmer2, Anna Kernder3, Claus Juergen Bauer1, Pantelis Karakostas1, Denada Bruci3, Adina Morar3, Anja Winklbauer2, Markus Essler2 and Valentin S. Schäfer2, 1Clinic of Internal Medicine III, Department of Rheumatology, University Hospital of Bonn, Bonn, Germany, Bonn, Germany, 2University Hospital Bonn, Bonn, Germany, 3University Hospital Düsseldorf, Düsseldorf, Nordrhein-Westfalen, Germany

    Background/Purpose: Vascular adhesion protein-1 (VAP-1) is a transmembrane adhesion molecule with oxidative deamination functionality, which is expressed in vascular smooth muscle cells and endothelial cells.…
  • Abstract Number: 1624 • ACR Convergence 2024

    Prognostic Value of Baseline 18F-FDG PET/CT Scan in Giant Cell Arteritis with Large Vessel Involvement

    Julio Sánchez-Martín1, Javier Loricera2, Isabel Martinez-Rodriguez3, ivan Ferraz-Amaro4, Nestor Martinez-Amador5, Remedios Quirce-Pisano5, Fernando Lopez-Gutierrez6 and Ricardo Blanco-Alonso7, 1Hospital Universitario 12 de Octubre, Madrid, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Nuclear Medicine, Hospital Universitario Marques de Valdecilla,IDIVAL, Santander, Cantabria, Spain, 4Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, 5Department of Nuclear Medicine, Hospital Universitario Marqués de Valdecilla, Molecular Imaging Group, IDIVAL, Santander., Santander, Spain, 6Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 7Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan has become a very useful diagnostic tool in patients with GCA with large vessel involvement. However,…
  • Abstract Number: 1054 • ACR Convergence 2023

    Immune Checkpoint Inhibitor Induced Polymyalgia Rheumatica Demonstrates a Similar Scintigraphic Appearance to Classical Polymyalgia Rheumatica on 18F-Fluorodeoxyglucose PET/CT

    David Liew1, Aurora Poon1, Christopher McMaster2, Russell Buchanan1, Victor Yang1, Andrew Scott1 and Claire Owen3, 1Austin Health, Heidelberg, Australia, 2Austin Health, Pascoe Vale South, Australia, 3Austin Health, Malvern East, Australia

    Background/Purpose: Of the rheumatic immune-related adverse events that follow immune checkpoint inhibitor (ICI) cancer immunotherapy, de novo PMR-like episodes without inflammatory arthritis (ICI-PMR) appear to…
  • Abstract Number: 1646 • ACR Convergence 2023

    The Real-World Experience of Combined Cranial and Large Vessel FDG-PET/CT in the Investigation of Giant Cell Arteritis

    Keren Port1, Ivan Ho Shon1, Sally Ayesa1, Rachel Langford1, Olivia Bennett1, Andrew Csillag1, Stacey Fredericks1, Luz Palacios-Derflingher2, Eva Wegner1 and Anthony Sammel1, 1The Prince of Wales Hospital, Sydney, Australia, 2University of New South Wales, Sydney, Australia

    Background/Purpose: GCA is a systemic medium-large vessel vasculitis (M-LVV) involving the cranial arteries, aorta and its major branches. Recent studies have shown that PET/CT including…
  • Abstract Number: 1890 • ACR Convergence 2023

    Use of Artificial Intelligence to Diagnose Polymyalgia Rheumatica on 18F-FDG Whole Body PET/CT in Patients with Atypical Clinical Features

    Emily Martin1, Christopher McMaster1, Saskia Rowson1, Victor Yang1, Aurora Poon1, Bonnia Liu1, Jessica Leung2, Andrew Scott1, David Liew1 and Claire Owen3, 1Austin Health, Heidelberg, Australia, 2Austin Health, Preston, Australia, 3Austin Health, Malvern East, Australia

    Background/Purpose: PET/CT is a highly sensitive and specific test for diagnosing PMR.(1) This study investigated the utility of 18F-FDG whole body PET/CT in patients presenting…
  • Abstract Number: 2394 • ACR Convergence 2023

    18f-FDG-PET/CT for Giant Cell Arteritis Detection of Large Vessel Vasculitis: What Should We Take into Consideration? Analytical Study of the Arteser Registry

    Paula V. Estrada-Alarcón1, Marta Domínguez2, Rafael Benito Melero-Gonzalez3, Eugenio De Miguel4, Maria. T Silva-Diaz5, Jesús Alejandro Valero6, Ismael González7, Julio Sanchez Martin8, Javier Narvaez9, Eva Galindez-Agirregoikoa10, javier Mendizábal11, lydia Abasolo12, Javier Loricera8, Alejandro Muñoz13, Santos Castañeda14, Patricia Moya15, patricia Moran Alvarez16, Vanesa Navarro17, Carles Galisteo18, Ivette Casafont-Solé19, Jose Andres Roman Ivorra20, TAREK CARLOS SALMAN MONTE21, Margarida Rocha22, Carlota Laura Iñiguez23, Alicia García24, Cristina Campos25, María Alcalde26, Antonio Juan Mas27, Francisco Javier Prado28, Ricardo Blanco29 and On Behalf of ARTESER Working Group30, 1Hospital de San Juan Despí Moisès Broggi, Barcelona, Spain, 2Sociedad Española de Reumatología, Madrid, Spain, 3CHU Vigo, O Carballino, Spain, 4Hospital Universitario La Paz, Madrid, Spain, 5Complexo Hospitalario Universitario A Coruña, A Coruña, Spain, 6Department of Rheumatology, Hospital Universitario Donostia, San Sebastián, Spain, 7Hospital Universitario de León, León, Spain, 8Hospital Universitario Marqués de Valdecilla, Santander, Spain, 9Hospital Universitario de Bellvitge, Barcelona, Spain, 10Basurto University Hospital, Bilbao, Spain, 11Complejo Hospitalario de Navarra, Pamplona, Spain, 12Hospital Clínico San Carlos, Madrid, Spain, 13Hospital universitario Virgen del Rocío, El Viso de Alcor, Spain, 14Hospital Universitario de la Princesa, Madrid, Spain, 15Hospital de Santa Creu i Sant Pau, Barcelona, Spain, 16Hospital Ramón y Cajal, Madrid, Spain, 17H Moisès Broggi, Sant Joan Despí, Barcelona, Spain, 18Hospital Universitario Parc Taulí, Sabadell, Spain, 19Hospital Germans Trias i Pujol, Badalona, Spain, 20Hospital Universitari i Politècnic la Fe, Valencia, Spain, 21Hospital del Mar/Parc de Salut Mar-IMIM, Barcelona, Spain, 22Osakidetza, Bilbo, Spain, 23Hospital Universitario Lucus Augusti, Lugo, Spain, 24Hospital Universitario de Canarias, Islas Canarias, 25Rheumatology Unit, Hospital General Universitario de Valencia, Valencia, Spain, 26Hospital Severo Ochoa, Madrid, Spain, 27Hospital Universitario Son Llàtzer, Mallorca, Spain, 28Research department Hospital Infantil de México Federico Gómez, Mexico City, Mexico, 29Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 30SER, Spain

    Background/Purpose: Imaging studies in patients with giant cell arteritis (GCA) and suspected large vessel vasculitis (LVV) are sensitive, increasingly available, and less aggressive than temporal…
  • Abstract Number: 2411 • ACR Convergence 2023

    C-X-C Motif Chemokine Receptor 4-targeted Molecular Imaging in Giant Cell Arteritis – a Head-to-head Comparison with FDG PET

    Matthias Froehlich1, Sebastian E. Serfling2, Michael Gernert3, Konstanze V. Guggenberger4, Takahiro Higuchi2, Samuel Samnick2, Marc Schmalzing5, Andreas K. Buck2, Thorsten Bley4 and Rudolf A. Werner2, 1Rheumatology/Clinical Immunology, Department of Internal Medicine II, University of Würzburg, Würzburg, Germany, 2Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany, 3Medical Department II, Rheumatology, University Hospital Würzburg, Würzburg, Germany, 4Institute of Diagnostic and Interventional Radiology, University Hospital Würzburg, Würzburg, Germany, 5University Hospital, Rheumatology/Clinical Immunology, Department of Internal Medicine II, Würzburg, Germany

    Background/Purpose: 2-[18F]fluoro-2-deoxy-D-glucose(FDG) is the reference PET radiotracer for detecting inflammation in giant cell arteritis (GCA). C-X-C motif chemokine receptor 4 (CXCR4)-directed PET, however, allows for…
  • Abstract Number: 0480 • ACR Convergence 2022

    Treatment of Giant Cell Arteritis Patients with Ultra-short Glucocorticoids and Tocilizumab: Role of Imaging in a Prospective Study

    Francesco Muratore1, Giulia Cassone2, Chiara Marvisi3, ELENA GALLI1, Luigi Boiardi1, GIULIA BESUTTI1, Lucia Spaggiari1, MASSIMILIANO CASALI1, Pamela Mancuso1, Annibale Versari1, Paolo Giorgi Rossi1 and Carlo Salvarani4, 1Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Reggio Emilia, Italy, 2Università di Modena e Reggio Emilia, Modena, Italy, 3Università di Modena e Reggio Emilia and National Institute of Arthritis & Musculoskeletal & Skin Diseases, National Institutes of Health, Bethesda, MD, 4Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia, Università di Modena e Reggio Emilia, Reggio Emilia, Italy

    Background/Purpose: To evaluate the clinical and functional/morphological imaging response in a series of active large vessel (LV)-GCA patients treated with tocilizumab (TCZ) monotherapy after ultra-short-term…
  • Abstract Number: 0580 • ACR Convergence 2022

    18F-FDG PET-MR Characterization of Aortitis in the IL1rn-/- Mouse Model of Giant-Cell Arteritis

    Samuel Deshayes1, Caroline Baugé2, Pierre-Antoine Dupont2, Christophe Simard2, Hubert De Boysson1, Alain Manrique2 and Achille Aouba1, 1Department of Internal Medicine, UR4650 PSIR, Normandie Univ, UNICAEN, CHU de Caen Normandie, Caen, France, 2UR4650 PSIR, Normandie Univ, UNICAEN, Caen, France

    Background/Purpose: Metabolic imaging is routinely used to demonstrate aortitis in patients with giant-cell arteritis. We aimed to investigate aortitis in BALB/c IL1rn-/- mice, a preclinical…
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