Abstracts tagged "New Therapeutics and animal models"

Abstract Number: 1223 • 2019 ACR/ARP Annual Meeting
Enteral Administration of ALLN-346, a Recombinant Urate-degrading Enzyme, Decreases Serum Urate in a Pig Model of Hyperuricemia
Danica Grujic¹, Kateryna Pirzynowska ², Paulina Szczurek ³, Stefan Pierzynowski ², Aditi Desphande ⁴, Olha Drahanchuck ⁵, Nadia Mosiichuk ⁶ and Jarek Wolinski ⁷, ¹Allena Pharmaceuticals, Boston, ²Lund University, Anara AB,/SGPlus, Lund, Sweden, ³National Research Institute of Animal Production, Vitanano Sp. z o.o./PROF,, Balice, Poland, ⁴Allena Pharmaceuticals, Newton, MA, ⁵Polish Academy of Sciences, Vitanano Sp. z o.o./PROF,, Jablonna, Poland, ⁶Lund University, Lund, Sweden, ⁷Polish Academy of Sciences, Vitanano Sp. z o.o./PROF, Jablonna, Poland
Background/Purpose: Uric acid homeostasis is determined as a balance between production, intestinal secretion and renal excretion. Around 2/3 of uric acid is excreted by the…

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Abstracts tagged "New Therapeutics and animal models"

Enteral Administration of ALLN-346, a Recombinant Urate-degrading Enzyme, Decreases Serum Urate in a Pig Model of Hyperuricemia