ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "neutrophils and toll-like receptors"

  • Abstract Number: 1006 • 2018 ACR/ARHP Annual Meeting

    Physical Activity at Lower Intensities Reduces Localized IL-1b in a Murine Model of Gout By Systemically Down-Regulating TLR2 Expression on Circulating Neutrophils and Suppressing CXCL1 Expression

    Kyle Jablonski1, Nicholas A. Young2, Bianca Sandoval3, Ifeoma Okafor4, Emily Schwarz3, Caitlin Henry3, Peter Harb3, Anuradha Kalyanasundaram5, Wael Jarjour6 and Naomi Schlesinger7, 1The Ohio State University Wexner Medical Center, Columbus, OH, 2Immunology and Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, 3Rheumatology and Immunology, Columbus, OH, 4Rheumatology and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, 5Physiology and Cell Biology, The Ohio State University, Columbus, OH, 6Department of Rheumatology and Immunology, The Ohio State University Wexner Medical Center, Columbus, OH, 7Department of Medicine/Rheumatology Division, Rutgers- Robert Wood Johnson Medical School, New Brunswick, New Brunswick, NY

    Background/Purpose: Exercise was originally believed to exacerbate inflammation in rheumatic disease, however, recent studies have shown that regular physical activity is anti-inflammatory. In gout, there…
  • Abstract Number: 1731 • 2013 ACR/ARHP Annual Meeting

    Treatment Of Innate Immune Arthritis With a Toll-Like Receptor 7 Agonist Requires Type I Interferon

    Maripat Corr1, Tomoko Hayashi2, Dennis A. Carson3, Howard Cottam4 and Joshua Yang3, 1Medicine, Univ of California-San Diego, La Jolla, CA, 2Medicine, UCSD School of Medicine, La Jolla, CA, 3UCSD School of Medicine, La Jolla, CA, 4ucsd School of Medicine, La Jolla, CA

    Background/Purpose: We previously demonstrated that repeated administration of the low molecular weight Toll-like receptor (TLR) 7 agonist (1V136) substantially reduces arthritic inflammation in mice.  Here…
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ACR Pediatric Rheumatology Symposium 2020

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