Abstracts tagged "Neutrophil Extracellular Traps and neutrophils"

Abstract Number: 290 • 2017 ACR/ARHP Annual Meeting
Characterization of Neutrophil Subsets and Neutrophil Extracellular Traps in Pyogenic Arthritis, Pyoderma Gangrenosum and Acne (PAPA) Syndrome
Pragnesh Mistry¹, Carmelo Carmona-Rivera¹, Nickie Seto¹, Monica Purmalek¹, Amanda Ombrello², Ivona Aksentijevich², Daniel L. Kastner² and Mariana J. Kaplan¹, ¹Systemic Autoimmunity Branch, NIAMS/NIH, Bethesda, MD, ²Inflammatory Disease Section, NHGRI/NIH, Bethesda, MD
Background/Purpose: Pyogenic arthritis, pyoderma gangrenosum and acne (PAPA) syndrome is an autosomal dominant autoinflammatory disorder caused by mutations in the PSTPIP1/CD2BP1 gene. PAPA syndrome is…
Abstract Number: 2265 • 2016 ACR/ARHP Annual Meeting
NET-Inducing Capacity Is a Biomarker in ANCA-Associated Vasculitis Independent of ANCA Antibodies
Tineke Kraaij¹, Sylvia Kamerling¹, Jaap Bakker², Francesca Brunini³, Charles Pusey³, Hans Ulrich Scherer⁴, René E.M. Toes⁵, Ton Rabelink¹, Cees van Kooten¹ and Onno Teng¹, ¹Nephrology, Leiden University Medical Center, Leiden, Netherlands, ²Clinical Chemistry, Leiden University Medical Center, Leiden, Netherlands, ³Imperial College, London, United Kingdom, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁵Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Neutrophil extracellular traps (NETs) play an important role in the pathogenesis of ANCA-associated vasculitis (AAV). Sera of MPO-ANCA or PR3-ANCA positive patients can induce…
Abstract Number: 1370 • 2015 ACR/ARHP Annual Meeting
CD40/CD40L Pathway Is Associated with Increased Oxidative Burst and Neutrophil Extracellular Traps Release in Behcet´s Disease
Sandro F. Perazzio^1,2, Paulo Vitor Soeiro Pereira³, Alexandre W.S. Souza⁴, Antonio Condino-Neto³ and Luis Eduardo C. Andrade⁵, ¹Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, ²Fleury Medicine and Health, Sao Paulo, Brazil, ³Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ⁵Immunology Division, Fleury Medicine and Health, São Paulo, Brazil
Background/Purpose: Previous studies suggested that unknown plasma factors increase oxidative burst in Behçet’s disease (BD), but little is known about neutrophil extracellular traps (NET) formation.…

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