Abstracts tagged "neutrophil"

Abstract Number: 685 • 2019 ACR/ARP Annual Meeting
Neutrophil Lymphocyte Ratio as a Marker for Immune Complex-Driven Inflammation in Patients with Systemic Lupus Erythematosus
Bobby Kwanghoon Han¹, Katherine Wysham ², Anders Bengtsson ³, Muhsen Al-Ani ¹, Grant Hughes ¹, Jenna Thomason ¹, Bernard Ng ⁴, Mark Wener ⁵ and Christian Lood ¹, ¹University of Washington, seattle, ²Veterans Health Administration Puget Sound, Seattle WA, Seattle, ³Lund University, Lund, Sweden, ⁴University of Washington, Veterans Affairs Puget Sound Health Care System, Seattle, WA, ⁵University of Washington, Seattle, WA
Background/Purpose: Neutrophils play a crucial role in pathogenesis of systemic lupus erythematosus (SLE). Recently, neutrophil to lymphocyte ratio (NLR) has been studied as a biomarker…
Abstract Number: 2809 • 2019 ACR/ARP Annual Meeting
Single-Cell RNA Sequencing of Murine Neutrophils Identifies a Transcriptional Continuum (“Neutrotime”) Across Biological Compartments
Ricardo Grieshaber-Bouyer¹, Giuseppina Stifano ², Pierre Cunin ³, Anaïs Levescot ⁴, Nathan Nelson-Maney ⁴, Rachel Blaustein ⁵, Paul Monach ⁶, Peter Nigrovic ⁷ and ImmGen Consortium ⁸, ¹Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; Department of Orthopedics, Heidelberg University Hospital, Heidelberg, Germany, Boston, MA, ²Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA, Boston, ³Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Boston, MA, ⁵Brigham and Women's Hospital, Boston, ⁶Brigham and Women's Hospital, Boston, MA, ⁷Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA ; Department of Medicine, Division of Immunology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA., Boston, ⁸Harvard Medical School, Boston
Background/Purpose: Neutrophils are key first responders of innate immunity, participating in both defense and inflammatory disease. Phenotypic heterogeneity is recognized but the existence of bone…

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