Abstracts tagged "Neuroendocrine Immune (NEI) and rheumatoid arthritis (RA)"

Abstract Number: 451 • ACR/ARHP Annual Meeting 2012
Pilot Study of Stimulation of the Cholinergic Anti-Inflammatory Pathway with an Implantable Vagus Nerve Stimulation Device in Patients with Rheumatoid Arthritis
Frieda A. Koopman¹, Sanda Miljko², Simeon Grazio³, Sekib Sokolovic⁴, Kevin Tracey⁵, Yaakov Levine⁶, Ralph Zitnik⁶ and Paul-Peter Tak⁷, ¹Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, ²University Clinical Hospital, Mostar, Bosnia, ³Clinical Hospital Center Sestre Milosrdnice, Zagreb, Croatia, ⁴Rheumatology, University Clinical Center, Sarajevo, Bosnia, ⁵Feinstein Institute for Medical Research, Manhasset, NY, ⁶SetPoint Medical Corporation, Valencia, CA, ⁷Academic Medical Center / currently also GlaxoSmithKline, Amsterdam, Netherlands
Background/Purpose: The inflammatory reflex regulates innate and adaptive immunity (Andersson O, Tracey K, Annu. Rev. Immunol. 2012; 30:313). Activation of its efferent arm (the Cholinergic…