ACR Meeting Abstracts
Abstract Number: 898 • ACR/ARHP Annual Meeting 2017
Jeremy Tilstra1, Rachael Gordon2, Shinu John3, Brady Marburger2, Sheldon Bastacky4, Kevin Nickerson2 and Mark Shlomchik5, 1Rheumatology, Univ of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3Moderna Therapeutics, Cambridge, MA, 4Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, 5Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Toll-like receptor (TLR) signaling is a central to lupus pathogenesis. GWAS studies have repeatedly identified components of TLR signaling pathway in SLE patients. Furthermore,…