Abstracts tagged "nephritis and toll-like receptors"

Abstract Number: 898 • 2017 ACR/ARHP Annual Meeting
B Cell Specific TLR9 Suppresses Disease in Murine Lupus
Jeremy Tilstra¹, Rachael Gordon², Shinu John³, Brady Marburger², Sheldon Bastacky⁴, Kevin Nickerson² and Mark Shlomchik⁵, ¹Rheumatology, Univ of Pittsburgh Medical Center, Pittsburgh, PA, ²University of Pittsburgh, Pittsburgh, PA, ³Moderna Therapeutics, Cambridge, MA, ⁴Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, ⁵Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Toll-like receptor (TLR) signaling is a central to lupus pathogenesis. GWAS studies have repeatedly identified components of TLR signaling pathway in SLE patients. Furthermore,…

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Abstracts tagged "nephritis and toll-like receptors"

B Cell Specific TLR9 Suppresses Disease in Murine Lupus