Abstracts tagged "nephritis and tolerance"

Abstract Number: 2974 • 2017 ACR/ARHP Annual Meeting
B Cell Binding Autoreactive VH4.34 Antibodies Are Specific to Lupus, Consist of Diverse Isotypes, and Are Associated with High Disease Activity and Lupus Nephritis
Scott Jenks¹, Joseph Marcus², Kevin Cashman¹ and Ignacio Sanz³, ¹Emory University School of Medicine and Lowance Center for Human Immunology, Atlanta, GA, ²San Antonio Uniformed Services Health Education Consortium, San Antonio, TX, ³Rheumatology and Lowance Center for Human Immunology, Emory University School of Medicine and Lowance Center for Human Immunology, Atlanta, GA
Background/Purpose: SLE is characterized by the dysregulation of humoral immunity including high levels of autoreactive IgG VH4.34 antibodies recognized by the rat anti-human idiotypic antibody…

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Abstracts tagged "nephritis and tolerance"

B Cell Binding Autoreactive VH4.34 Antibodies Are Specific to Lupus, Consist of Diverse Isotypes, and Are Associated with High Disease Activity and Lupus Nephritis