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Abstracts tagged "nephritis and race/ethnicity"

  • Abstract Number: 1897 • ACR/ARHP Annual Meeting 2018

    Single Cell RNA Expression in Lupus Nephritis Comparing African-American and Caucasian Patients Identifies Differential Expression of Interferon Pathway

    Andrea Fava1, Yuji Zhang2, Nir Hacohen3, Arnon Arazi4, Celine C. Berthier5, Deepak Rao6, Michael Brenner7, David Wofsy8, Anne Davidson9, Matthias Kretzler10, David Hildeman11, E. Steve Woodle12, Betty Diamond13 and Michelle Petri14, 1Departement of Medicine - Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, 3Harvard Medical School, Boston, MA, 4Broad Institute, Cambridge, MA, 5Nephrology, Division of Nephrology, University of Michigan Medical Center, Ann Arbor, MI, 6Human Immunology Center, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 7Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 8Rheumatology, University of California, San Francisco, San Francisco, CA, 9Center for Autoimmunity, Musculoskeletal & Hematopoietic Diseases, Feinstein Institute for Medical Research, Manhasset, NY, 10Division of Nephrology, University of Michigan, Ann Arbor, MI, 11University of Cincinnati, Cincinnati, OH, 12University of Cincinnati College of Medicine, Cincinnati, OH, 13The Feinstein Institute for Medical Research, Manhasset, NY, 14Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose: African-American (AA) ethnicity is associated with a 3-fold higher risk of developing systemic lupus erythematosus (SLE). In addition, there is an increased risk of…

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