Abstracts tagged "nephritis and neutrophils"

Abstract Number: 860 • 2014 ACR/ARHP Annual Meeting
Inhibition of G Protein βγ Signaling Inhibits Nephritis in Lupus Prone Mice
Teresa Owen¹, Javier Rangel-Moreno², Jesi To³, Bruce Goldman⁴, Alan Smrcka³ and Jennifer H. Anolik⁵, ¹Rheumatology, University of Rochester, Rochester, NY, ²Medicine- Allergy, Immunology, and Rheumatology, University of Rochester, Rochester, NY, ³Pharmacology & Physiology, University of Rochester, Rochester, NY, ⁴Pathology, University of Rochester, Rochester, NY, ⁵Medicine- Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY
Background/Purpose G protein-coupled receptors (GPCRs), including chemokine receptors on leukocytes, signal through G protein Gβγ subunits. An important target of Gβγ is phosphoinositide 3 kinase γ…

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Abstracts tagged "nephritis and neutrophils"

Inhibition of G Protein βγ Signaling Inhibits Nephritis in Lupus Prone Mice