Abstracts tagged "Neonatal lupus and pregnancy"

Abstract Number: 2047 • 2016 ACR/ARHP Annual Meeting
Impact of in Utero Hydroxychloroquine Exposure on the Risk of Cutaneous Neonatal Lupus Erythematosus
Julie Barsalou¹, Nathalie Costedoat-Chalumeau², Adey Berhanu³, Cesar Fors-Nieves⁴, Ummara Shah⁵, Patrick Brown⁶, Carl Laskin⁷, Nathalie Morel⁸, Kateri Levesque⁹, Jill P. Buyon¹⁰, Earl Silverman⁶ and Peter M. Izmirly¹¹, ¹Pediatric Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ²Internal Medicine, Cochin University Hospital, Paris, France, ³Rheumatology Fellowship Program, NYU Langone Medical Center/NYU School of Medicine, New York, NY, ⁴Division of Rheumatology, NYU School of Medicine, New York, NY, ⁵Medicine, Strong Memorial Hospital, University of Rochester, Rochester, NY, ⁶University of Toronto, Toronto, ON, Canada, ⁷Medicine, Rheumatology and Obstetrics and Gynecology, University of Toronto and LifeQuest Centre for Reproductive Medicine, Toronto, ON, Canada, ⁸Internal Medicine Department, Cochin Hospital, “René-Descartes Paris V” University, Paris, France, ⁹Internal Medicine, CHU Ste-Justine, Montréal, QC, Canada, ¹⁰Medicine, Tisch Hospital, New York, NY, ¹¹New York University School of Medicine, New York, NY
Background/Purpose: Histopathologic studies of cutaneous neonatal lupus erythematosus (cNLE) lesions usually show interface dermatitis. Hydroxychloroquine (HCQ) is an effective treatment for interface dermatitis seen in…
Abstract Number: 2453 • 2016 ACR/ARHP Annual Meeting
The Prevention, Screening, and Treatment of Congenital Heart Block from Neonatal Lupus: A Survey of Provider Practices
Megan E. B. Clowse¹, Amanda M. Eudy², Bonnie L. Bermas³, Eliza Chakravarty⁴, Lisa R. Sammaritano⁵ and Christina D. Chambers⁶, ¹Rheumatology, Duke University School of Medicine, Durham, NC, ²Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ⁴Edmond, OK, ⁵Rheumatology, Hospital for Special Surgery, New York, NY, ⁶Pediatrics, University of California, San Diego, La Jolla, CA
Background/Purpose: There are presently no official guidelines about the prevention, screening, and treatment of congenital heart block (CHB) due to maternal Ro antibodies. The objective…
Abstract Number: 2123 • 2015 ACR/ARHP Annual Meeting
Incidence and Prognosis of Neonatal and Late-Onset Dilated Cardiomyopathy Associated with Cardiac Neonatal Lupus
Kateri Levesque^1,2, Nathalie Morel³, Alice Maltret⁴, Gabriel Baron⁵, Mohamed Hamidou⁶, Pauline Orquevaux⁷, Jean Charles Piette⁸, Francois Barriere⁹, Jérome Lebidois⁴, Laurent Fermont⁴, Olivier Fain¹⁰, Arnaud Theulin¹¹, Francois Sassolas¹², Philippe Pézard¹³, Gaëlle Guettrot-Imbert¹⁴, Delphine Le Mercier¹⁵, Sophie Georgin-Lavialle¹⁶, Christophe Deligny¹⁷, Eric Hachulla¹⁸, Luc Mouthon¹⁹, Philippe Ravaud²⁰, Elisabeth Villain⁴, Damien Bonnet²¹ and Nathalie Costedoat-Chalumeau³, ¹Internal Medicine, CHU Ste-Justine, Montréal, QC, Canada, ²Medicine Interne, Hopital Cochin, Paris, France, ³Internal Medicine Department, Cochin Hospital, “René-Descartes Paris V” University, Paris, France, ⁴Cardiology, Groupe Hospitalier Necker - Enfants Malades, Paris, France, ⁵Hôpital Hôtel Dieu, Paris, France, ⁶Internal Medicine Department, Nantes University Hospital, Nantes, France, ⁷Hu Robert Debre, CHU Reims, Reims, France, ⁸Internal Medicine Department, University Hospital “Pitié-Salpêtrière”, “Pierre et Marie Curie Paris VI” University, Paris, France, ⁹Pediatry, CHU Nantes, Nantes, France, ¹⁰Internal Medicine, Hospital J. Verdier, Bondy, France, ¹¹Internal medicine, CHRU Strasbourg, Strasbourg, France, ¹²Cardiology, CHU Lyon, Lyon, France, ¹³Pediatric cardiologist, CHU Angers, Angers, France, ¹⁴Internal Medicine, Hopital Saint-Antoine, Paris, France, ¹⁵Obstetrics and gynecology, Hopital Necker, Paris, France, ¹⁶Internal medicine, Hopital Tenon, Paris, France, ¹⁷Rhumatologie Et Médecine Interne, Centre hospitalier Universitaire de Fort de France, Fort de France, Martinique, ¹⁸Service de Médecine Interne, Centre National de Référence des Maladies Systémiques Rares, Hôpital Claude Huriez, CHRU Lille, Lille, France, ¹⁹Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, Paris, France, ²⁰Rheumatology, Paris, France, ²¹Pediatric cardiologist, Hopital Necker, Paris, France
Background/Purpose: Dilated cardiomyopathy (DCM) is a well-known complication of cardiac neonatal lupus syndrome and is associated with a high mortality rate. Its risk factors are…
Abstract Number: 2515 • 2015 ACR/ARHP Annual Meeting
MEK5/ERK5, a Lynchpin of Human Cardiac Fibroblast Transdifferentiation to a Scarring Phenotype in Autoimmune Congenital Heart Block
Andrew Markham¹, Robert Clancy², Mukundan Attur³ and Jill P. Buyon², ¹Medicine, New York University School of Medicine, New York, NY, ²Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ³Rheumatology Research, NYU - Hospital for Joint Diseases, New York, NY
Background/Purpose: Transplacental passage of maternal autoantibodies (Ab) reactive with the SSA/Ro-SSB/La ribonucleoprotein complex is associated with the development of cardiac injury in the fetus passively…

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