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Abstracts tagged "neonatal disorders and registries"

  • Abstract Number: 2861 • 2013 ACR/ARHP Annual Meeting

    Accounting For Parental Load and Identification Of Multiple Risk Variants For Anti-Ro Congenital Heart Block Through High-Density Genotyping Of Immune-Related Loci

    Robert M. Clancy1, Jill P. Buyon2, Nathalie Costedoat-Chalumeau3, Antonio Brucato4, Kateri Levesque5, Véronique Ramoni6, Miranda C. Marion7, Mary Comeau8, Satria Sajuthi9, Paula S. Ramos10, Robert P. Kimberly11, Timothy D. Howard12 and Carl D. Langefeld13, 1Medicine, New York University School of Medicine, New York, NY, 2Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 3Internal Medicine, Hopital Cochin, Paris, France, 4Internal Medicine, USC Internal Medicine, Ospedali Riuniti, Bergamo, Italy, 5Medicine Interne, Hopital Cochin, Paris, France, 6Rheumatology, Rheumatology University of Pavia, Pavia, Italy, 7Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, 8Wake Forest University Health Sciences, Winston-Salem, NC, 9Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 10Department of Medicine, Medical University of South Carolina, Charleston, SC, 11Clinical Immun & Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 12Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, 13Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC

    Background/Purpose:  Anti-Ro associated congenital heart block (CHB) exhibits a 33% concordance rate in monozygotic twins, 17.5% recurrence of disease and a high sibling risk ratio…
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