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Abstracts tagged "Myositis and statins"

  • Abstract Number: 230 • ACR/ARHP Annual Meeting 2012

    Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCoR) Antibody in Necrotizing Myopathy and the Role of Statins

    Ashima Malik1, Rohit Aggarwal2, Zengbiao Qi3, Noreen Fertig4, Diane Koontz5, Rufus W. Burlingame6, David Lacomis7 and Chester V. Oddis8, 1Rheumatology, University of Pittsburgh, Pittsburgh, PA, 2Medicine / Rheumatology, University of Pittsburgh, Pittsburgh, PA, 3Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 4University of Pittsburgh, Pittsburgh, PA, 5Department of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 6Rheumatology Research, INOVA Diagnostics, Inc., San Diego, CA, 7Neurology, University of Pittsburgh Medical Ctr, Pittsburgh, PA, 8Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Statin use is associated with myalgias, muscle weakness and elevated muscle enzymes, but recent reports of a statin-induced immune-mediated necrotizing myopathy (IMNM) have been…

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