Abstracts tagged "Myositis and statins"

Abstract Number: 230 • 2012 ACR/ARHP Annual Meeting
Hydroxy-3-Methylglutaryl-Coenzyme A Reductase (HMGCoR) Antibody in Necrotizing Myopathy and the Role of Statins
Ashima Malik¹, Rohit Aggarwal², Zengbiao Qi³, Noreen Fertig⁴, Diane Koontz⁵, Rufus W. Burlingame⁶, David Lacomis⁷ and Chester V. Oddis⁸, ¹Rheumatology, University of Pittsburgh, Pittsburgh, PA, ²Medicine / Rheumatology, University of Pittsburgh, Pittsburgh, PA, ³Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Department of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁶Rheumatology Research, INOVA Diagnostics, Inc., San Diego, CA, ⁷Neurology, University of Pittsburgh Medical Ctr, Pittsburgh, PA, ⁸Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Statin use is associated with myalgias, muscle weakness and elevated muscle enzymes, but recent reports of a statin-induced immune-mediated necrotizing myopathy (IMNM) have been…

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