Abstracts tagged "myositis and neroptosis"

Abstract Number: 122 • 2019 ACR/ARP Annual Meeting
Inhibition of Necroptosis Suppresses Muscle Cell Death and Inflammatory Infiltrate, and Improves Muscle Strength in Experimental Polymyositis
Mari Kamiya¹, Kimito Kawahata ², Hitoshi Kohsaka ¹ and Fumitaka Mizoguchi ¹, ¹Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan, Tokyo, Japan, ²Rheumatology and Allergology, St. Marianna University School of Medicine, Tokyo, Japan
Background/Purpose: In polymyositis (PM), CD8+ cytotoxic T lymphocytes (CTLs) are assumed to induce muscle cell death. We presumed that the injured muscle cells release pro-inflammatory…

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Abstracts tagged "myositis and neroptosis"

Inhibition of Necroptosis Suppresses Muscle Cell Death and Inflammatory Infiltrate, and Improves Muscle Strength in Experimental Polymyositis