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Abstracts tagged "myopathy and polymyositis/dermatomyositis (PM/DM)"

  • Abstract Number: 282 • 2016 ACR/ARHP Annual Meeting

    From ‘immune Mediated Necrotizing Myopathy’ to ‘antibody-Mediated Necrotizing Myositis: Towards the Pathogenic Role of Anti-SRP and Anti-Hmgcr Antibodies’

    Yves Allenbach1, Louiza Arouche-Delaperche2, Corinna Preusse3, Gillian Butler Browne2, Nicolas Champtiaux4, Kuberaka Mariampillai5, Aude Rigolet6, Peter Hufnagl7, Norman Zerbe8, Thierry Maisonobe9, Damien Amelin2, Sarah Leonard-louis10, Charles Duyckaerts11, Bruno Eymard12, Hans-Hilmar Goebel3, Laurent Drouot13, Olivier Boyer14, Olivier Benveniste2,5 and Werner Stenzel3, 1Pitié-Salpêtrière University Hospital, AP-HP, Department of Internal Medicine and Clinical Immunology, Paris, France, Paris, France, 2Sorbonne Universités UPMC Univ Paris 06, Myology research center, INSERM UMRS974, CNRS FRE3617, Pitié-Salpêtrière University Hospital, Paris, France, Paris, France, 3Charité - Universitätsmedizin, Department of Neuropathology, Berlin, Germany, Berlin, Germany, 4Department de Internal Medicine and Clinical Immunology, Hôpital Pitié-Salpêtrière, AP-PH, UPMC, Paris, France, 5Assistance Publique - Hôpitaux de Paris, Pitié-Salpêtrière University Hospital, Department of Internal Medicine and Clinical Immunology, Hospital University Department: inflammation, immunopathology and biotherapy (DHU i2B), Paris, France, Paris, France, 6Internal Medicine, Pitié-Salpêtrière University Hospital, Paris, France, 7Pathology departmen, Charite Hospital, Berlin, Germany, 8Department of Pathology, Charite Hospital, Berlin, Germany, 9Pitié-Salpêtrière University Hospital, AP-HP, Department of Neuropathology, Paris, France, Paris, France, 10Assistance Publique - Hôpitaux de Paris, Pitié-Salpêtrière University Hospital, Department of Neuropathology, Paris, France, Paris, France, 11Neuropathology, Pitie-Salpetriere Hospital, Paris, France, 12Department of Neurology, Hôpital Pitié-Salpêtrière, AP-PH, UPMC, Paris, France, 13Immunology, INSERM U905, University of Rouen, Rouen, France, 14Immunology, Inserm 905 & Institute for Biomedical Research, University of Rouen, Rouen, France

    Background/Purpose: Immune mediated necrotizing myopathy (IMNM) has been recently added as a new entity among dermatomyositis, polymyositis and sporadic inclusion body myositis. IMNM is defined…
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