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Abstracts tagged "Myopathies"

  • Abstract Number: 0940 • ACR Convergence 2022

    Effect of an 8-week Tailored Physical Therapy Program on Sexual Function in Women with Systemic Sclerosis and Idiopathic Inflammatory Myopathies: A Pilot Controlled Study

    Barbora Hermankova1, Maja Spiritovic1, Sabina Oreska2, Hana Storkanova2, Karel Pavelka3, Ladislav Šenolt4, Jiří Vencovský4, Radim Becvar2 and Michal Tomcik2, 1Institute of Rheumatology, Department of Physiotherapy, Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, 2Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 3Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Praha, Czech Republic, 4Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic

    Background/Purpose: Systemic rheumatic diseases like systemic sclerosis (SSc) and idiopathic inflammatory myopathies (IIM) may affect all aspects of life, including sexual health. However, no non-pharmacological…
  • Abstract Number: 1233 • ACR Convergence 2022

    Ultrasound Is Reliable in the Assessment of Muscle Echogenicity in Patients with Rheumatic Diseases: Results of a Multicenter International Web-based Study

    Andrea Di Matteo1, Erica Moscioni2, Maria Giovanna Lommano1, Edoardo Cipolletta1, Gianluca Smerilli1, Sonia Farah1, Carla Airoldi3, Sibel Aydin4, Becciolini Andrea5, Karina Bonfiglioli6, Marina Carotti7, Greta Carrara8, Tomas Cazenave9, Davide Corradini10, Micaela Ana Cosatti11, Juan Josè de Agustin12, Giulia Maria Destro Castaniti13, Marco Di Carlo1, Eleonora Di Donato5, Luca Di geso14, Ashley Elliott15, Daniela Fodor16, Francesca Francioso1, Alessandra Gabba17, Cristina Hernández-Díaz18, Rudolf Horvath19, Jana Hurnakova19, Diogo Jesus20, Josefina Marin21, Maria Victoria Martire22, Riccardo Mashadi-Mirza23, Marco Massarotti24, Alice Andreea Musca25, Jagdish Nair26, Tadashi Okano27, Ioannis Papalopoulos28, Javier Eduardo Rosa21, Marcos Rosemffet29, João Rovisco30, Davide Rozza8, Fausto Salaffi1, Crescenzio Scioscia31, Carlo Alberto Scirè8, Maria-Magdalena Tamas32, Shun Tanimura33, Lucio Ventura-Rios18, Catalina Villota-Eraso34, Orlando Villota35, Paraksevi V Voulgari36, Florentin Ananu Vreju37, Gentiana Vukatana37, Johana Zacariaz Hereter21, Anna Zanetti8, Walter Grassi1 and Emilio Filippucci1, 1Polytechnic University of Marche, Rheumatology Unit, Department of Clinical and Molecular Sciences, "Carlo Urbani" Hospital, Jesi, Italy, 2Polytechnic University of Marche, Jesi, Italy, 3Hospital Provincial, Rosario, Argentina, 4University of Ottawa, Rheumatology, Ottawa, Canada, Ottawa, ON, Canada, 5Department of Medicine, Internal Medicine and Rheumatology Unit, Azienda Ospedaliero Universitaria di Parma, Parma, Italy, 6Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 7Department of Radiology, Ospedali Riuniti, Università Politecnica delle Marche, Ancona, Italy, 8Epidemiology Unit, Italian Society of Rheumatology, Milano, Italy, 9Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 10Rheumatology Unit, University Clinic AOU Cagliari, Cagliari, Italy, 11CEMIC, Centro de educación médica e investigaciones médicas "Norberto Quirno", Buenos Aires, Argentina, 12Vall D'hebron University Hospital, Barcelona, Spain, 13Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, Rheumatology section, University of Palermo, Palermo, Italy, 14Ospedale Madonna del Soccorso, Department of Internal Medicine, San Benedetto del Tronto, Italy, 15Centre for Experimental Medicine, Queen's University, Belfast, Northern Ireland, United Kingdom, 162nd Internal Medicine Department, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania, 17Local Health Unit (ASL), Oristano, Italy, 18Division de Reumatologia. Instituto Nacional de Rehabilitacion "Luis Guillermo Ibarra Ibarra", Ciudad de México, Mexico, 19Department of Paediatric and Adult Rheumatology, University Hospital Motol, Prague, Czech Republic, 20Rheumatology Department, Centro Hospitalar de Leiria, Leira, Portugal, 21Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 22San Roque Hospital, La Plata, Buenos Aires, Argentina, 23Radiology Department, A.O. Ospedali Riuniti Marche Nord, Pesaro, Italy, 24Department of Rheumatology, University Hospitals Dorset NHS Foundation Trust, Christchurch Hospital, Christchurch, United Kingdom, 25Department of Rheumatology - Colentina Clinical Hospital, Bucharest, Romania, 26Rheumatology, Liverpool University Hospitals Foundation Trust, Liverpool, United Kingdom, 27Department of Orthopedic Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan, 28Department of Rheumatology, Clinical Immunology and Allergy, University Hospital of Heraklion, Heraklion, Greece, 29Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, 30Rheumatology Department, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 31Department of Emergency and Organ Transplantations-Rheumatology Unit, University of Bari "Aldo Moro", Bari, Italy, 32Department of Rheumatology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania, 33Rheumatology Department, Hokkaido Medical Center for Rheumatic Diseases, Sapporo, Japan, 34IPS Servicio integral de reumatología e inmunología Dr Orlando Villota, Pasto, Colombia, 35Division of Rheumatology, Fundación Hospital San Pedro, Pasto, Colombia, 36Department of Rheumatology, School of Health Science, Faculty of Medicine, University of Ioannina, Ioannina, Greece, 37Rheumatology Department, University of Medicine and Pharmacy of Craiova, Craiova, Romania, 37Rheumatology Unit; IRCCS Policlinico S. Orsola Malpighi, Bologna, Italy

    Background/Purpose: Studies have showed that an increased ultrasound (US) muscle echogenicity indicating fatty replacement/fibrosis of muscle tissue may represent an early indicator of muscle involvement associated…
  • Abstract Number: 1283 • ACR Convergence 2022

    Frequency of Checking Creatine Kinase in Patients on Statins with Elevated Transaminase for Early Detection of Statin Induced Myopathy

    ANJALI NIDHAAN, Andrei Hastings, david gonzalez, rajshri joshi, nathan gilbert and carolyn o'connor, Cleveland Clinic Akron General, Akron, OH

    Background/Purpose: Some of the most commonly reported side effects of statins (widely used lipid lowering agents) are muscle injury (incidence ranging from 0.1-20% based on…
  • Abstract Number: 1361 • ACR Convergence 2022

    Factors Associated with Medication-Free Remission in Juvenile Dermatomyositis

    Harneet Ghumman1, Asra Firdous1, Megan Quinlan-Waters1, Amy Cassedy2, Angela Merritt1, Hermine Brunner3, Alexei Grom1, Daniel Lovell1 and Sheila Angeles-Han1, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cincinnati Children's Hospital Medical Center, Cleveland, OH, 3Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Department of Pediatrics, Cincinnati, OH

    Background/Purpose: Juvenile dermatomyositis (JDM) is characterized by symmetric proximal muscle weakness, distinct rash, and a risk for calcinosis and multi-organ involvement. Treatment with systemic immunosuppression…
  • Abstract Number: 1637 • ACR Convergence 2022

    Association of Dermatomyositis with Cardiovascular Disease: A Case-Control Study in the All of Us Research Program

    Jill Shah1, Keya Shah2, Daniel Mazori1, Avrom Caplan1, Emily Hejazi1 and Alisa Femia1, 1Ronald O. Perelman Department of Dermatology, New York University Langone Health, New York, NY, 2Department of Medicine, NYU Langone Hospital - Long Island, Mineola, NY

    Background/Purpose: Previous studies on the association of dermatomyositis (DM) with cardiovascular (CV) disease have used combined idiopathic inflammatory myositis cohorts, included only non-United States (US)…
  • Abstract Number: 1660 • ACR Convergence 2022

    Skeletal Myopathy in Systemic Sclerosis Associates with Higher Disease Burden and Mortality

    Julie Paik1, Caoilfhionn Connolly1, Fredrick Wigley1 and Laura Hummers2, 1Johns Hopkins University, Baltimore, MD, 2Johns Hopkins Univerisity, Baltimore, MD

    Background/Purpose: Skeletal myopathy in systemic sclerosis (SSc) is poorly understood. The etiology of myopathy in SSc is heterogeneous and can result from an inflammation, disuse,…
  • Abstract Number: 1864 • ACR Convergence 2022

    Hepatitis B Exposure and Infection in Idiopathic Inflammatory Myopathies: Prevalence, Presentation, and Treatment Response

    Ana Valle1, Xianhong Xie2 and Shereen Mahmood3, 1Montefiore Medical Center, New York, NY, 2Department of Epidemiology & Population Health/Albert Einstein College of Medicine, Bronx, NY, 3Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY

    Background/Purpose: Hepatitis B (HBV) screening in patients with autoimmune conditions is vital prior to the initiation of immunosuppressive therapy given the risk of HBV reactivation.…
  • Abstract Number: 1871 • ACR Convergence 2022

    Hospitalization Outcomes for Acute Myocardial Infraction and Acute Heart Failure in Patients with Idiopathic Inflammatory Myopathies (IIM) from 2016-2019 National Inpatient Sample (NIS)

    Zi Ying Li1, Siyi Huang2, Kevin Xi3, Deepan Dalal4 and Anthony Reginato5, 1Roger Williams Medical Center, Providence, RI, 2UCSF Fresno, Fresno, CA, 3Brown University, Providence, 4Brown University School of Medicine, Providence, RI, 5Brown University, Providence, RI

    Background/Purpose: Cardiovascular disease was encountered in 15% of hospital admission from 2016-2017 for patients with idiopathic inflammatory myopathies (IIM) based on the National Inpatient Sample…
  • Abstract Number: 1877 • ACR Convergence 2022

    Nailfold Videocapillaroscopic Abnormalities Correlate with Disease Activity Measures and Cutaneous Damage in Patients with Idiopathic Inflammatory Myopathies

    Diane Zisa1, Aliza Bloostein1, Deanna Jannat-Khah, DrPH, MSPH1, Maurizio Cutolo2, Vanessa Smith3 and David Fernandez1, 1Hospital for Special Surgery, New York, NY, 2Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic Hospital, Genova, Italy, 3Department of Rheumatology, Ghent University Hospital – Department of Internal Medicine, Ghent University, Belgium – Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Gent, Belgium

    Background/Purpose: Nailfold videocapillaroscopy (NVC) is a non-invasive tool used to evaluate the microcirculation of patients with connective tissue diseases (CTDs). A specific combination of NVC…
  • Abstract Number: 0156 • ACR Convergence 2022

    Impact of Polymyositis and Dermatomyositis in Patients Admitted with Congestive Heart Failure: An Insight from the National Database

    Brinda Basida1, Sanket Basida2, Jasleen Kaur3, Urja Nagadia2, mahmoud mansour2, Palak Shah4 and Monil Majmundar5, 1DMC/Sinai Grace Hospital, Detroit, MI, 2University of Missouri, Columbia, MO, 3DMC/WSU, Saginaw, MI, 4Metropolitan Hospital Center, New York Medical College, New York, NY, 5University of Kansas Medical Center, Kansas City, KS

    Background/Purpose: Polymyositis (PM) and Dermatomyositis (DM) are systemic autoimmune diseases of inflammatory infiltrates in skeletal muscle resulting in chronic muscle weakness. Systemic involvement of the…
  • Abstract Number: 1882 • ACR Convergence 2022

    Efficacy of Immune-apheresis in Patients with Inflammatory Myopathies: A Case Series

    Kastriot Kastrati1, Hanien Rajab2, Anna Rader2, Elisabeth Anna Aichner2, Thomas Karonitsch2, Hans-Peter Kiener2, Michael Bonelli3, Daniel Aletaha4 and Helga Radner3, 1Division of Rheumatology, Vienna, Austria, 2Medical University Vienna, Vienna, Austria, 3Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, 4Medical University Vienna, Wien, Austria

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) comprise a heterogenous group of acquired autoimmune diseases characterised by inflammation of muscle and affection of other organs, including lung…
  • Abstract Number: 0164 • ACR Convergence 2022

    Anti-SSa/SSb and Ro52 Status and Pulmonary Function Tests in Patients with Interstitial Lung Disease and Idiopathic Inflammatory Myopathies

    Abdullah Ahmed1, Sonali Narain2, Ivana Ilic1, Can Hu3, Jaspreet Bhatti4 and Galina Marder5, 1Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, 2Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY, 3Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Fort Lee, NJ, 4Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY, 5Donald and Barbara Zucker School of Medicine at Hofstra/ Northwell, Great Neck, NY

    Background/Purpose: Interstitial lung disease (ILD) is a major cause of morbidity and mortality in patients with idiopathic inflammatory myositis (IIM). Anti-SSa/SSb and Ro52 are frequently…
  • Abstract Number: 1884 • ACR Convergence 2022

    Idiopathic Inflammatory Myopathies in Alaska Native/American Indian People in Alaska

    Vivek Mehta and Elizabeth Ferucci, Alaska Native Tribal Health Consortium, Anchorage, AK

    Background/Purpose: Racial disparities have been in noted in various autoimmune disorders. Indigenous North American populations have higher prevalence and severity of a number of autoimmune…
  • Abstract Number: 0166 • ACR Convergence 2022

    Detection of the Novel Autoantibodies Against Transcription Factor Sp4 Is Related with Low Risk of Cancer in Idiopathic Inflammatory Myopathy Patients

    Yuji Hosono1, Azusa Kojima1, Akira Ishii1, Mai Sugiyama1, Yuto Izumi1, Noriko Sasaki2, Chiho Yamada1 and Shinji Sato1, 1Tokai University School of Medicine, Isehara Kanagawa, Japan, 2Tokai University School of Medicine, sagamihara-city, Japan

    Background/Purpose: In idiopathic inflammatory myopathy (IIM), many kinds of autoantibodies are often detected and associated with each clinical phenotype. Recently, autoantibody against transcription factor Sp4…
  • Abstract Number: 1886 • ACR Convergence 2022

    Statin-induced Immune-mediated Miopathy: Treatment with Glucocorticoid-free Protocols and Role of Muscle Biopsy in the Follow-up

    David Martínez-López1, Piotr Szczęsny2, Inger Nennesmo3, Karina Gheorghe4, Antonella Notarnicola5, Helene Alexanderson6, Ingrid Lundberg7 and Maryam Dastmalchi8, 1Hospital Universitario Marqués de Valdecilla, Santander, Spain, 2Department of Rheumatology, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland. Department of Neurology, Medical University of Warsaw, Warsaw, Poland, 3Department of Pathology, Karolinska University Hospital,Pathology, Karolinska University Hospital., Stockholm, Sweden, 4Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet. Rheumatology, Karolinska University Hospital Stockholm, Sweden. Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 5Division of Rheumatology, Department of Medicine, Solna, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 6Karolinska Institutet, Stockholm, Sweden, 7Karolinska Universitetssjukhuset, Karolinska Institutet, Stockholm, Sweden, 8Karolinska University Hospital, Stockholm, Sweden

    Background/Purpose: Statin-induced immune mediated necrotizing myopathy (IMNM) is a recently identified autoimmune condition associated with anti-3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) antibodies, characterized by progressive muscle weakness leading…
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