ACR Meeting Abstracts

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Abstracts tagged "Myocardial Infarction"

  • Abstract Number: 1615 • ACR Convergence 2022

    Myocardial Infarction in Patients with Systemic Vasculitis and Population Controls: Characteristics and Overall Mortality

    Pavlos Stamatis1, Moman Mohammad2, David Erlinge2, Carl Turesson3, David Jayne4 and Aladdin Mohammad5, 1Department of Clinical Sciences Lund, Rheumatology, Lund University, Sweden, Larissa, Larisa, Greece, 2Department of Clinical Sciences Lund, Cardiology, Lund University, Lund, Sweden, 3Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 4University of Cambridge, Cambridge, United Kingdom, 5Rheumatology, Department of Clinical Sciences, Lund University, Lund, Sweden

    Background/Purpose: The deleterious effect of inflammation combined with glucocorticoid treatment may increase the risk for atherosclerotic events. The aims of this study were to investigate…
  • Abstract Number: 1817 • ACR Convergence 2022

    Acute Coronary Syndrome in Calcium Pyrophosphate Deposition Disease Patients: A Cross-sectional Study from the National Inpatient Sample

    Konstantinos Parperis1 and Bikash Bhattarai2, 1University of Cyprus Medical School, Nicosia, Cyprus, 2Valleywise Health, Phoenix, AZ

    Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) is a common crystal-induced arthritis characterized by the deposition of calcium pyrophosphate crystals in the articular tissues. Acute CPP…
  • Abstract Number: 1871 • ACR Convergence 2022

    Hospitalization Outcomes for Acute Myocardial Infraction and Acute Heart Failure in Patients with Idiopathic Inflammatory Myopathies (IIM) from 2016-2019 National Inpatient Sample (NIS)

    Zi Ying Li1, Siyi Huang2, Kevin Xi3, Deepan Dalal4 and Anthony Reginato5, 1Roger Williams Medical Center, Providence, RI, 2UCSF Fresno, Fresno, CA, 3Brown University, Providence, 4Brown University School of Medicine, Providence, RI, 5Brown University, Providence, RI

    Background/Purpose: Cardiovascular disease was encountered in 15% of hospital admission from 2016-2017 for patients with idiopathic inflammatory myopathies (IIM) based on the National Inpatient Sample…
  • Abstract Number: 1976 • ACR Convergence 2022

    Outcomes of the First Episode of STEMI in Rheumatoid Arthritis from the National Inpatient Sample Database 2016-2019

    Amar Suwal1, Biraj Shrestha2, Ibiyemi Oke2 and Anthony Donato2, 1Reading Hospital, Tower Health, Reading, PA, 2reading hospital- tower health, Reading, PA

    Background/Purpose: Patients with Rheumatoid arthritis (RA) have a higher burden of cardiovascular diseases (CVDs) than the general population, with most deaths resulting from myocardial infarctions.…
  • Abstract Number: 1915 • ACR Convergence 2021

    Risk of Cardiovascular Outcomes with Low-Dose Glucocorticoids in Patients with Rheumatoid Arthritis

    Brian Coburn1, Michael George1, Joshua Baker1, Jesse Hsu2, Qufei Wu1, Lang Chen3, Fenglong Xie3, Huifeng Yun4 and Jeffrey Curtis5, 1University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, Philadelphia, PA, 3University of Alabama at Birmingham, Birmingham, AL, 4University of Alabama Birmingham, Birmingham, AL, 5Division of Clinical Immunology and Rheumatology, Department of Medicine, Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Many guidelines recommend limiting glucocorticoids to short-term use in patients with rheumatoid arthritis (RA), but up to 40% of patients remain on glucocorticoids long-term.…
  • Abstract Number: 0446 • ACR Convergence 2021

    Clinical Characteristics, Including History of Myocardial Infarction and Stroke, Among US PMO Women Initiating Treatment with Romosozumab and Other Anti-osteoporosis Therapies

    Jay Lin1, Carrie Nielson1, Mary Oates1, Cynthia Deignan2 and Zhigang Yu1, 1Amgen Inc., Thousand Oaks, CA, 2Amgen, Inc., Agoura Hills, CA

    Background/Purpose: This study is an ongoing USFDA post-marketing requirement (2020-2024) to assess the impact of boxed warning on romosozumab (romo) treatment and the feasibility of…
  • Abstract Number: 1099 • ACR Convergence 2021

    Characteristics and Outcomes of Myocardial Infarction in Patients with Rheumatoid Arthritis, Systemic Lupus Erythematosus, Systemic Sclerosis, Gout and Osteoarthritis Patients Using the National Inpatient Sample Database from 2002-2018

    Sonia Gupta1, Vinay thallapally2, Sarah Aurit2, Rouhin sen3 and Joseph Nahas2, 1Creighton University School of Medicine, Omaha, NE, 2Creighton University, Omaha, NE, 3Colorado University Anschutz Medical Campus, Denver, CO

    Background/Purpose: Patients with the autoimmune rheumatic disease have an increased risk of acute myocardial infarction (MI). Our study was designed to compare the prevalence, characteristics…
  • Abstract Number: 1833 • ACR Convergence 2021

    Risk of Major Adverse Cardiovascular Events (MACE) with Biologic and Targeted Synthetic Antirheumatic Agents in Psoriatic Arthritis: A Systematic Review and Network Meta-analysis

    Muhammad Ajmal1, Jawad Bilal1, Syed Arsalan Ahmed Naqvi2, Irbaz Bin Riaz3, Zaina Shahid4, Kaneez Zahra Rubab Khakwani1, Yi-Shao Liu5, Sandipan Bhattacharjee5, Roxanne Bogucka5, Noureen Asghar6 and Kent Kwoh1, 1University of Arizona, Tucson, AZ, 2Dow University of Health Sciences, Karachi, Pakistan, 3Mayo Clinic, Phoenix, AZ, 4Lehigh Valley Health Network, Allentown, PA, 5University of Texas at Austin, Austin, TX, 6Dow University of Health Sciences, Karachi

    Background/Purpose: The efficacy of biologics and targeted synthetic disease modifying antirheumatic agents approved for treatment of psoriatic arthritis (PsA) is well documented, but cardiovascular safety…
  • Abstract Number: 0239 • ACR Convergence 2020

    Adjudicated MACE and VTE in the Filgotinib RA Program: Integrated Analysis from Phase 2 and 3 Clinical Trials

    Christina Charles-Schoeman1, Sang-Cheol Bae2, Arvind Chopra3, Stanley Cohen4, Jeffrey R Curtis5, Jacques-Eric Gottenberg6, Edward C Keystone7, Kunihiro Yamaoka8, Peter Nash9, J-Abraham Simon-Campos10, William Stohl11, Michael Weinblatt12, Rene Westhovens13, Jeff Siegel14, Iyabode Tiamiyu14, Lei Ye14, Deyuan Jiang14, Franziska Matzkies14, Angelika Jahreis14, John S. Sundy14 and Jon Giles15, 1University of California, Los Angeles, Los Angeles, CA, 2Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, 3Center for Rheumatic Diseases, Pune, India, 4University of Texas Southwestern Medical School at Dallas, and Metroplex Clinical Research Center, Dallas, TX, 5Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 6Strasbourg University Hospital, Strasbourg, France, 7Mount Sinai Hospital, Toronto, ON, Canada, 8Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan, 9School of Medicine Griffith University, Brisbane, Queensland, Australia, 10Köhler & Milstein Research, Mérida, Mexico, 11University of Southern California Keck School of Medicine, Los Angeles, CA, 12Brigham and Women's Hospital, Boston, MA, 13University Hospitals Leuven, Belgium, Leuven, Belgium, 14Gilead Sciences, Inc., Foster City, CA, 15Columbia University, New York, NY

    Background/Purpose: Filgotinib (FIL)—an oral, selective Janus kinase 1 inhibitor (JAKi)—improved RA signs and symptoms in three phase 3 trials. Despite the efficacy of FIL and…
  • Abstract Number: 1181 • ACR Convergence 2020

    Gains in Cardiovascular Risk Knowledge Through Web Based Educational Intervention for Rheumatoid Arthritis Patients

    Meenakshi Jolly1, Courtney O'Brien1, Aman Kugasia2, Anna Gorfin3, Lauren Klebek3, Joshlean Fair3 and Joel Block1, 1Rush University, Chicago, IL, 2Arthritis Clinic of Cypress and Katy, PA, Katy, TX, 3Rush University, Chicago

    Background/Purpose: Cardiovascular disease (CVD) is a leading cause of mortality in rheumatoid arthritis (RA). Ischemic heart disease in RA is often silent and precedes myocardial…
  • Abstract Number: 1390 • ACR Convergence 2020

    Outcomes of Systemic Sclerosis Patients Who Were Primarily Admitted for Acute Myocardial Infarction from 2016 to 2017: Insights from the National Inpatient Sample

    Atefeh Vafa1, Omid Behnamfar2 and Yih Chang Lin3, 1University of South Florida, Tampa, FL, 2University of California San Diego, La Jolla, CA, 3University of South Florida, Morsani College of Medicine, Tampa, FL

    Background/Purpose: Several systemic autoimmune rheumatic diseases have been shown to increase coronary artery disease (CAD) risk, notable rheumatoid arthritis and systemic lupus erythematosus.  However, data…
  • Abstract Number: 1424 • ACR Convergence 2020

    Outcomes of Hospitalizations for Acute Myocardial Infarction in Patients with ANCA Associated Vasculitis from the National Inpatient Sample

    Atefeh Vafa1, Marielys Figueroa Sierra1, Omid Behnamfar2, Hamayon Babary1, Suraiya Afroz1 and Yih Chang Lin3, 1University of South Florida, Tampa, FL, 2University of California San Diego, La Jolla, CA, 3University of South Florida, Morsani College of Medicine, Tampa, FL

    Background/Purpose: Several studies in the past have shown significantly increased risks of cardiovascular disease in patients with ANCA associated vasculitis (AAV). This association is thought…
  • Abstract Number: 1630 • ACR Convergence 2020

    Long-term Safety of Tildrakizumab in Patients with Moderate to Severe Plaque Psoriasis: Incidence of Confirmed Major Adverse Cardiovascular Events Through 3 Years (148 Weeks) from Two Phase 3 Trials

    Lars Iversen1, Christopher EM Griffiths2, Andrea Peserico3, Ignasi Pau-Charles4, Andrew Blauvelt5, Diamant Thaçi6 and Kristian Reich7, 1Aarhus University Hospital, Aarhus, Denmark, 2The University of Manchester, Manchester, United Kingdom, 3DIMED University of Padua, Padua, Italy, 4Almirall R&D, Barcelona, Spain, 5Oregon Medical Research Center, Portland, OR, 6Institute and Comprehensive Center for Inflammation Medicine, University of Lübeck, Lübeck, Germany, 7Translational Research in Inflammatory Skin Diseases, Institute for Health Services Research in Dermatology and Nursing, University Medical Center Hamburg-Eppendorf, and Skinflammation®, Hamburg, Germany

    Background/Purpose: Tildrakizumab (TIL) is a high-affinity anti–interleukin-23p19 monoclonal antibody that is approved for the treatment of moderate to severe plaque psoriasis. The objective of this…
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