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Abstracts tagged "myeloperoxidase (MPO) and vasculitis"

  • Abstract Number: 1769 • ACR/ARHP Annual Meeting 2017

    Incidence, Predictors, and Outcome of Diffuse Alveolar Hemorrhage in Patients with MPO-ANCA Positive Microscopic Polyangiitis: A Multi-Center Retrospective Cohort Study

    Takashi Kida, Shunya Kaneshita, Takuya Inoue, Amane Nakabayashi, Yuji Kukida, Kazuki Fujioka, Hidetake Nagahara, Makoto Wada, Takahiro Seno, Masataka Kohno and Yutaka Kawahito, Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan

    Background/Purpose: In patients with microscopic polyangiitis (MPA), a variety of pulmonary lesions including diffuse alveolar hemorrhage (DAH), airways disease and interstitial lung disease (ILD) have…
  • Abstract Number: 1082 • ACR/ARHP Annual Meeting 2015

    ANCA-Negative and Myeloperoxidase-ANCA-Positive Patients with Granulomatosis with Polyangiitis: Clinical Manifestations and Risk of Relapse

    Eli Miloslavsky1, Na Lu2, Sebastian Unizony3, Hyon K. Choi3, Peter A. Merkel4, Philip Seo5, Robert F. Spiera6, Carol A. Langford7, Gary S. Hoffman7, Cees Kallenberg8, E. William St.Clair9, Nadia Tchao10, Fernando Fervenza11, Paul A. Monach12, Ulrich Specks13 and John H. Stone14, 1Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, 2Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 4Penn Vasculitis Center, Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, 5Division of Rheumatology, Johns Hopkins, Baltimore, MD, 6Rheumatology, Hospital for Special Surgery, New York, NY, 7Rheumatology, Cleveland Clinic, Cleveland, OH, 8Rheumatology/Clin Immunol AA21, Univer Med Center Groningen, Groningen, Netherlands, 9Rheumatology and Immunology, Duke University, Durham, NC, 10ITN, San Francisco, CA, 11Mayo Clinic, Rochester, MN, 12Rheumatology, Boston University School of Medicine, Boston, MA, 13Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, MN, 14Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA

    Background/Purpose: Recent studies in ANCA-associated vasculitis (AAV) have suggested that classification based on ANCA type (PR3 versus MPO) may represent a more clinically relevant division…
  • Abstract Number: 1773 • ACR/ARHP Annual Meeting 2014

    Otolaryngologic Lesions Are Not Rare and Closely Related with Pachymeningitis and Cranial Neuropathy in MPO-ANCA Associated Vasculitis

    Takahiro Nunokawa1, Naoto Yokogawa2, Kota Shimada1 and Shoji Sugii2, 1Department of Rheumatic diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan, 2Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan

    Background/Purpose: Recently several case reports of serous otitis media (SOM), hypertrophic pachymeningitis (HP) and cranial neuropathy (CN) have been reported in connection with MPO-ANCA associated…
  • Abstract Number: 734 • ACR/ARHP Annual Meeting 2013

    The Significance Of Anti-Myeloperoxidase and Anti-Proteinase 3 Antibodies In The Absence Of Anti-Neutrophil Cytoplasmic Antibody Immunofluorescence Positivity

    Deepak A. Rao1, Joseph F. Merola1, William R. O'Brien1, Kevin Wei1, Samuel U. Takvorian2, Paul F. Dellaripa3 and Peter H. Schur1, 1Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Internal Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 3Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Identification of serum anti-neutrophil cytoplasmic antibodies (ANCA) for the detection of ANCA-associated vasculitis (AAV) is often performed by screening with indirect immunofluorescence (IF), followed…
  • Abstract Number: 1536 • ACR/ARHP Annual Meeting 2012

    Clinical Features of Patients with Anti-Neutrophil Cytoplasmic Autoantibodies Targeting Native Myeloperoxidase Antigen

    Yuji Yamanishi1, Toshiko Ito-Ihara2, Shigeto Kobayashi3, Peter Y. Shane4, Gary S. Firestein5, Hiroshi Hashimoto6 and Kazuo Suzuki7, 1Division of Rheumatology, Hiroshima Rheumatology Clinic, Hiroshima, Japan, 2Department of Clinical Innovative Medicine, Translational Research Center, Kyoto University Hospital, Kyoto, Japan, 3Department of Internal Medicine, Juntendo University Koshigaya Hospital, Tokyo, Japan, 4Tokyo Medical and Dental University, Tokyo, Japan, 5Div of Rheumatology, UCSD School of Medicine, La Jolla, CA, 6Juntendo Tokyo Koto Geriatric Center, Tokyo, Japan, 7National Institute of Infectious Diseases, Tokyo, Japan

    Background/Purpose: ANCA is a useful diagnostic marker in systemic vasculitic disorders with small-vessel involvement, but depending on the particular test used the myeloperoxidase (MPO)-ANCA results…

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