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Abstracts tagged "muscle strength and myopathy"

  • Abstract Number: 1353 • 2018 ACR/ARHP Annual Meeting

    Autophagy Marker LC3 Accumulates in Immune-Mediated Necrotizing Myopathy Muscle Fibres

    Margherita Giannini1, Francesco Girolamo2, Anna Lia2, Angela Amati2, Luigi Serlenga2, Dario D'Abbicco3, Marilina Tampoia4, Maria Trojano2 and Florenzo Iannone1, 1D.E.T.O., Rheumatology Unit - D.E.T.O. - University of Bari (ITALY), Bari, Italy, 2Department of Basic Medical Sciences, Neuroscience and Sense Organs, Unit of Neurophysiopathology, Policlinico Hospital, University of Bari, BARI, Italy, 3Institute of General Surgery ‘G Marinaccio’ (DETO), Policlinico Hospital, University of Bari, BARI, Italy, 4Laboratory of Clinical Pathology, University Hospital of Bari, BARI, Italy

    Background/Purpose: To investigate the expression of autophagy marker LC3, localization of macrophages and accumulation of misfolded proteins in myofibres of immune-mediated necrotizing myopathy (IMNM) muscle…
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