Abstracts tagged "multiple imputation"

Abstract Number: 2137 • 2014 ACR/ARHP Annual Meeting
Linear Extrapolation of Missing Radiographic Progression Scores Does Not Spuriously overestimate overall Radiographic Progression in Rheumatoid Arthritis
Iris Markusse¹, Robert Landewé^2,3, Meilien Ho⁴, Martin Jenkins⁴ and Desiree van der Heijde⁵, ¹Leiden University Medical Center, Leiden, Netherlands, ²Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, ³Atrium Medical Center, Heerlen, Netherlands, ⁴AstraZeneca R&D Alderley Park, Macclesfield, United Kingdom, ⁵Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose : Linear Extrapolation (LE) is a frequently applied method to impute missing radiographic data in trials. However, there is frequent critique that LE overestimates…

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Abstracts tagged "multiple imputation"

Linear Extrapolation of Missing Radiographic Progression Scores Does Not Spuriously overestimate overall Radiographic Progression in Rheumatoid Arthritis