ACR Meeting Abstracts

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Abstracts tagged "MRI"

  • Abstract Number: 241 • 2013 ACR/ARHP Annual Meeting

    Exploratory Factor Analysis Of a Parsimonious Medial Cartilage Damage Index Reveals One Factor Associated With Radiographic Severity and Symptoms: Data From The Osteoarthritis Initiative

    Grace H. Lo1, Lori Lyn Price2,3, Ming Zhang4, Jeffrey B. Driban5, Daniel Harper4 and Timothy E. McAlindon6, 1VA HSR&D Center for Innovations in Quality, Effectiveness and Safety; Medical Care Line and Research Care Line; Department of Medicine, Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX, 2Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 3Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 4Rheumotology, Tufts Medical Center, Boston, MA, 5Rheumatology, Tufts Medical Center, Boston, MA, 6Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: The cartilage damage index (CDI) is a parsimonious method of measuring articular cartilage approximating regional cartilage volume based on 18 locations within the knee,…
  • Abstract Number: 1800 • 2013 ACR/ARHP Annual Meeting

    Persistent Fatty Lesions In The Vertebrae In Ankylosing Spondylitis Favor Subsequent New Syndesmophytes: Imaging Results Of a Phase III, Randomized, Placebo-Controlled Study

    Kay-Geert A. Hermann1, Xenofon Baraliakos2, Jürgen Braun3, Stephen Xu4 and Benjamin Hsu4, 1Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, 2Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Janssen Research & Development, LLC., Spring House, PA

    Background/Purpose: In ankylosing spondylitis (AS), it is hypothesized that stepwise pathologic changes in the spine begin with active inflammation, then fatty degeneration (Fat), leading to…
  • Abstract Number: 221 • 2013 ACR/ARHP Annual Meeting

    Detection Of Cerebral Microvascular Lesions In Patients With Acute Phase Neuropsychiatric Systemic Lupus Erythematosus By 7Tesla MRI

    Nobuhito Sasaki1, Okinori Murata1, Yukari Ninomiya1, Yuka Oikawa1, Hitoshi Kobayashi1, Kohei Yamauchi1, Makoto Sasaki2, Takashi Sawai3 and Yutaka Nakamura1, 1Division of Pulmonary medicine, Allergy and Rheumatology, Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Japan, 2Division of Ultrahigh Field MRI, Iwate Medical University School of Medicine, Morioka, Japan, 3Department of Pathology, Iwate Medical University School of Medicine, Morioka, Japan

    Background/Purpose: The cerebral microvascular lesions of patients with neuropsychiatric systemic lupus erythematosus (NPSLE) have not been fully elucidated. The 7Tesla MR scanner has high image…
  • Abstract Number: 1803 • 2013 ACR/ARHP Annual Meeting

    Is Site Of Back Pain Related To Location Of Inflammatory and Structural Lesions On MRI In Patients With Chronic Back Pain?

    Manouk de Hooge1, Rosaline van den Berg2, Floris van Gaalen2, Victoria Navarro-Compán2, Monique Reijnierse3, Karen Fagerli4, Maureen C. Turina5, Maikel van Oosterhout6, Roberta Ramonda7, Tom Huizinga2 and Désirée van der Heijde1, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands, 4Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 6Rheumatology, GHZ Hospital, Gouda, Netherlands, 7Rheumatology Unit, University of Padova, Padova, Italy

    Background/Purpose: Pain has found to be related to inflammatory lesions in thoracic, lumbar and sacroiliac joints (SIJ) sites and to structural lesions in the SIJ…
  • Abstract Number: 222 • 2013 ACR/ARHP Annual Meeting

    Comparison Of Whole Body Versus Targeted Magnetic Resonance Imaging For Assessing Disease Activity and Damage In Idiopathic Inflammatory Myopathies

    Adam Schiffenbauer1, Evrim Turkbey2, Lisa G. Rider1, Suvimol Hill2, Irene Z. Whitt3, Songtao Liu2, David A. Bluemke2 and Frederick W. Miller1, 1Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 2NIH, Bethesda, MD, 3Rheumatology and Immunology, Duke, Durham, NC

    Background/Purpose: In the idiopathic inflammatory myopathies (IIM) MRI imaging is traditionally focused on the proximal upper or lower extremities.  Whole body MRI (WBMRI) is a…
  • Abstract Number: 1684 • 2013 ACR/ARHP Annual Meeting

    Early Combination Immunosuppression and Serial Non-Invasive Imaging Improves Outcome In Takayasu Arteritis

    Taryn Youngstein1, Michael Quinn1, James Peters1 and Justin C. Mason2, 1Rheumatology Unit, Hammersmith Hospital, Imperial College London, London, United Kingdom, 2Rheumatology and Vascular Sciences, Hammersmith Hospital, Imperial College London, London, United Kingdom

    Background/Purpose: Takayasu arteritis (TA) affects the aorta and its branches, pre-disposing to stenoses and aneurysmal dilatation. While morbidity remains high, evidence for efficacy of immunosuppressive…
  • Abstract Number: 236 • 2013 ACR/ARHP Annual Meeting

    Hip Bone Marrow Lesions In Asymptomatic and Osteoarthritic Adults: Prevalence, Risk Factors and Significance

    L Dawson1, Yuanyuan Wang1, Anita Wluka2, Kim Bennell3, Andrew Teichtahl4 and Flavia Cicuttini2, 1Monash University, Melbourne, Australia, 2Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia, 3University of Melbourne, Melbourne, Australia, 4Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia

    Background/Purpose: Bone marrow lesions (BMLs) at the knee have an important role in the pathogenesis of osteoarthritis (OA), being associated with increased pain, accelerated cartilage…
  • Abstract Number: 1539 • 2013 ACR/ARHP Annual Meeting

    Inflammation In The Posterior Elements Of The Spine Is Infrequent In Patients With Recent Onset Axial Spondyloarthritis, Especially If No Inflammation In The Vertebral Bodies Is Observed

    Rosaline van den Berg1, Manouk de Hooge1, Monique Reijnierse2, Victoria Navarro-Compán1, Karen Fagerli3, Maureen Turina4, Maikel van Oosterhout5, Roberta Ramonda6, Floris van Gaalen1, Tom Huizinga1 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 5Rheumatology, GHZ Hospital, Gouda, Netherlands, 6Rheumatology Unit, University of Padova, Padova, Italy

    Background/Purpose: There is evidence that in almost all patients with longstanding and active ankylosing spondylitis (AS) inflammatory lesions in the posterior elements are as frequent…
  • Abstract Number: 237 • 2013 ACR/ARHP Annual Meeting

    The Association Of Radiographic Disease With Lesions On MRI In Lateral Compartment Knee Osteoarthritis: The Osteoathritis Initiative

    Barton L. Wise1, Jingbo Niu2, Felix Liu3, John A. Lynch4, Yuqing Zhang5, Ali Guermazi6, David T. Felson5, C. Kent Kwoh7 and Nancy E. Lane1, 1Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3University of California at San Francisco, San Francisco, CA, 4Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, 5Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 6Boston University, Boston, MA, 7School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose:   Lateral compartment knee tibio-femoral radiographic osteoarthritis (ROA) is associated with pain and disability, and the epidemiology of this form of knee OA is…
  • Abstract Number: 1515 • 2013 ACR/ARHP Annual Meeting

    Influence Of Taking Structural Lesions Into Account In Addition To Inflammatory Lesions On MRI Of The Sacroiliac Joints On The Classification Of Patients With Possible Axial Spondyloarthritis

    Rosaline van den Berg1, Manouk de Hooge1, Floris van Gaalen1, Victoria Navarro-Compán1, Monique Reijnierse2, Karen Fagerli3, Robert Landewé4,5, Maikel van Oosterhout6, Roberta Ramonda7, Tom Huizinga1 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 5Rheumatology, Atrium Medical Center, Heerlen, Netherlands, 6Rheumatology, GHZ Hospital, Gouda, Netherlands, 7Rheumatology Unit, University of Padova, Padova, Italy

    Background/Purpose: The ASAS definition of a positive MRI of the sacroiliac joints (MRI-SI+) for the classification of axial spondyloarthritis (axSpA) patients includes inflammatory lesions only1,2.…
  • Abstract Number: L19 • 2013 ACR/ARHP Annual Meeting

    Kellgren-Lawrence Grade (KL) 0 Vs. KL 1 Knees Differ in Their MRI Predictors of Subsequent Radiographic Osteoarthritis

    C.Kent Kwoh1, Ali Guermazi2, Tomoko Fujii3, Robert M. Boudreau3, Michael Hannon4, Jason Grago4, David Hunter5, Felix Eckstein6 and Frank Roemer7, 1Department of Medicine, The University of Arizona Arthritis Center, Tucson, AZ, 2Radiology, Boston University School of Medicine, Boston, MA, 3Epidemiology, University of Pittsburgh, Pittsburgh, PA, 4Medicine, University of Pittsburgh, Pittsburgh, PA, 5University of Sydney, Sydney, Australia, 6Paracelsus Medical University, Salzburg, Austria, 7Klinikum Augsburg, Augsburg, Germany

    Background/Purpose: Kellgren-Lawrence grade (KL) 1, defined by a questionable osteophyte and/or doubtful joint space narrowing, is thought to be an intermediate stage from non-OA (i.e.,…
  • Abstract Number: 1517 • 2013 ACR/ARHP Annual Meeting

    Different Imaging Abnormalities Suggestive Of Spondyloarthritis Are Present In Early Axial Spondyloarthritis. Data From The DESIR Cohort

    Anna Moltó1, Simon Paternotte2, Désirée van der Heijde3, Pascal Claudepierre4, Martin Rudwaleit5 and Maxime Dougados6, 1Cochin Hospital, Paris- Descartes University, Paris, France, 2Rheumatology Department, Paris- Descartes University, Cochin hospital, Paris, France, 3Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Rheumatology, Paris-Est University; LIC EA4393; APHP, Henri Mondor Hospital, Creteil, France, 5Endokrinologikum, Berlin, Germany, 6Université Paris René Descartes and Hôpital Cochin, Paris, France

    Background/Purpose: Patients can fulfil the ASAS (Assessment of SpondyloArthritiS) sets of criteria with either objective evidence of sacroiliac joint damage (X-Ray) or inflammation (MRI) (“imaging”…
  • Abstract Number: 128 • 2013 ACR/ARHP Annual Meeting

    Frequency Of Axial Spondyloarthropathy Among Patients Suffering From Fibromyalgia A Magnetic Resonance Immaging  Study With Application Of The Assessment Of Spondylo-Arthritis International Society Classification Criteria

    Jacob N. Ablin1, Iris Eshed2, Valerie Aloush1, Irena Wigler3, Dan Caspi1, Maria Likhter4, Mark Berman5, Yonatan Wolman1, Daphna Paran6, Marina Anouk7 and Ori Elkayam8, 1Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2Department of Radiology, Sheba Medical Center, Tel Hashomer, Israel, 3Department of Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 4Internal Medicine 6, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 5Internal Medicine F, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 6Rheumatology, Tel Aviv Sourasky Medical Ctr, Tel-Aviv university, Tel Aviv, Israel, 7Rheumatology, Tel Aviv Sourasky Medical Ctr, Tel-Aviv University, Tel Aviv, Israel, 8Rheumatology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Tel- Aviv, Israel

    Background/Purpose: Fibromyalgia Syndrome (FMS), considered the result of increased processing of pain by the central nervous system, is a non-inflammatory condition characterized by chronic, widespread…
  • Abstract Number: 1420 • 2013 ACR/ARHP Annual Meeting

    Induction Therapy With Adalimumab On Top Of An Aggressive Treat-To-Target Strategy With Methotrexate and Intraarticular Corticosteroid Reduces Radiographic Erosive Progression In Early Rheumatoid Arthritis, Even After Withdrawal Of Adalimumab. Results Of a 2-Year Trial (OPERA)

    Kim Hørslev-Petersen1, Lykke Midtbøll Ørnbjerg2, Merete Lund Hetland3, Peter Junker4, Jan Pødenphant5, Torkell Ellingsen6, Palle Ahlqvist7, Hanne M. Lindegaard8, Asta Linauskas9, Annette Schlemmer10, Mette Y. Dam11, Ib Hansen12, Tine Lottenburger7, Anette Jørgensen13, Sophine B. Krintel14, Johnny Raun15, Christian G. Ammitzbøll11, Julia Johansen14, Mikkel Østergaard16 and Kristian Stengaard-Pedersen11, 1Institute of Regional Health Services Research, University of Southern Denmark, Graasten, Denmark, 2Copenhagen Center for Arthritis Reasearch, Center for Rheumatology and Spine diseases, Glostrup Hospital, Copenhagen, Denmark, 3DANBIO, Center for Rheumatology and Spine Diseases, Glostrup Univ Hospital, Glostrup, Denmark, 4University of Southern Denmark, Odense, Denmark, 5Copenhagen University at Gentofte, Hellerup, Denmark, 6Silkeborg Regional Hospital, Silkeborg, Denmark, 7University of Southern Denmark, Vejle, Denmark, 8Department of Rheumatology, Odense University Hospital, Odense, Denmark, 9Vendsyssel Hospital, Hjørring, Denmark, 10Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, 11Arhus University Hospital, Aarhus, Denmark, 12Rheumatology, Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 13Rheumatology, Arhus University Hospital, Aarhus, Denmark, 14Copenhagen University and Glostrup Hospital, Copenhagen, Denmark, 15University of Southern Denmark, Graasten, Denmark, 16Copenhagen University Hospital Glostrup, Copenhagen, Denmark

    Background/Purpose: In a randomized double-blind, placebo-controlled 2-year investigator-initiated trial of patients with early rheumatoid arthritis¹ (RA) we aimed to investigate if additional adalimumab (ADA) for…
  • Abstract Number: 2753 • 2013 ACR/ARHP Annual Meeting

    Relationship Of Pre-Radiographic MRI Lesions With Prevalent Frequent Knee Symptoms and Incident Persistent Knee Symptoms In Persons At Higher Risk For Knee Osteoarthritis

    Leena Sharma1, Joan S. Chmiel1, Orit Almagor1, Dorothy D. Dunlop2, Marc C. Hochberg3, Charles Eaton4, C. Kent Kwoh5, Rebecca D. Jackson6, Joan M. Bathon7, Ali Guermazi8, Frank Roemer9, Michel Crema8, W. Jerry Mysiw6 and Michael C. Nevitt10, 1Northwestern University, Chicago, IL, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3Medicine, University of Maryland School of Medicine, Baltimore, MD, 4Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, 5School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 6Ohio State University, Columbus, OH, 7Columbia University, New York, NY, 8Boston University, Boston, MA, 9Klinikum Augsburg, Augsburg, Germany, 10Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA

    Background/Purpose: The clinical significance of pre-radiographic MRI lesions in persons at risk for knee OA is unclear.  Understanding whether such lesions are inconsequential or early…
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