Abstracts tagged "MRI"

Abstract Number: 1177 • 2014 ACR/ARHP Annual Meeting
Evaluation of a Simplified Version of the Rheumatoid Arthritis Magnetic Resonance Imaging Score (RAMRIS) Comprising 5 Joints (RAMRIS5)
Dr. Philipp Sewerin¹, Dr. Christoph Schleich², Dr. Christian Buchbender³, Dr. Falk Miese³, Dr. Ralph Brinks⁴, Prof. Dr. Matthias Schneider⁵, Prof. Dr. Gerald Antoch⁶ and Prof. Dr. Benedikt Ostendorf¹, ¹Department of Rheumatology, Univ. Duesseldorf, Düsseldorf, Germany, ²Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Duesseldorf, Germany, ³Department of Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany, ⁴Univ Duesseldorf, Düsseldorf, Germany, ⁵Department of Rheumatology, Univ. Duesseldorf, Duesseldorf, Germany, ⁶Department Diagnostic and Interventional Radiology, Univ. Duesseldorf, Düsseldorf, Germany
Background/Purpose Semi-quantitative measurement of inflammatory pathologies of the hand in magnetic resonance images (MRI) is a mandatory, but time-consuming task for MRI controlled studies in…
Abstract Number: 209 • 2014 ACR/ARHP Annual Meeting
Physical Performance and Obesity Measures Are Associated with Tibial Cartilage Volume and Explains the Sex Difference in Cartilage Volume
Benny Samuel Eathakkattu Antony¹, Alison Venn², Flavia Cicutinni³, Lyn March⁴, Leigh Blizzard⁵, Terry Dwyer⁶, Marita Cross⁷, Graeme Jones⁸ and Changhai Ding⁸, ¹Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ²Epidemiology, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ³Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia, ⁴Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁵Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁶Director, Murdoch Children's Research Institute, Melbourne, Australia, ⁷University of Sydney Institute of Bone and Joint Research, Royal North Shore Hospital, Sydney, Australia, ⁸Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose The factors associated with knee cartilage volume in younger population are insufficiently explored. The aims of this study were to describe the associations between…
Abstract Number: 2938 • 2014 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Placebo-Controlled, 16-Week Study of Subcutaneous Golimumab in Patients with Active Nonradiographic Axial Spondyloarthritis
J Sieper¹, D van der Heijde², M Dougados³, Walter P. Maksymowych⁴, J Boice⁵, G Bergman⁵, S Curtis⁵, A Tzontcheva⁵, S Huyck⁵ and HH Weng⁵, ¹University Clinic Benjamin Franklin, Berlin, Germany, ²Leiden University Medical Center, Leiden, Netherlands, ³Paris-Descartes University, Paris, France, ⁴Department of Medicine, University of Alberta, Alberta, AK, ⁵Merck & Co., Inc., Whitehouse Station, NJ
Background/Purpose Axial spondyloarthritis (axSpA), including ankylosing spondylitis and nonradiographic axial SpA (nr-axSpA), is a chronic inflammatory disease marked by back pain and progressive spinal stiffness.…
Abstract Number: 1688 • 2014 ACR/ARHP Annual Meeting
Early Detection of Left Ventricular Morphological, Functional Abnormalities and Myocardial Characteristics in Systemic Sclerosis without Cardiac Symptoms Using Cardiac Magnetic Resonance Imaging: A Preliminary Report
Kaita Sugiyama¹, Hitomi Kobayashi², Yasuyuki Kobayashi³, Yosuke Nagasawa⁴, Natsumi Ikumi², Takamasa Nozaki⁴, Hirotake Inomata², Hidetaka Shiraiwa², Hiromi Karasawa², Noboru Kitamura⁴, Mitsuhiro Iwata⁴, Yoshihiro Matsukawa² and Masami Takei⁴, ¹Nihon University School of Medicine, Tokyo, Japan, ²Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan
Background/Purpose Systemic sclerosis (SSc) is associated with an increased prevalence of cardiac involvement despite often being clinically silent. Cardiac involvement is a major factor in…
Abstract Number: 1179 • 2014 ACR/ARHP Annual Meeting
Efficacy of Tocilizumab in Patients with Rheumatoid Arthritis: Sequential Evaluation Using Whole-Body Magnetic Resonance Imaging
Michihito Kono¹, Shinsuke Yasuda¹, Kazumasa Ohmura¹, Tomoko Fukui¹, Sanae Shimamura¹, Ikuma Nakagawa¹, Atsushi Noguchi¹, Haruki Shida¹, Toshiyuki Watanabe¹, Yuka Shimizu¹, Takashi Kurita¹, Kenji Oku¹, Toshiyuki Bohgaki¹, Olga Amengual¹, Tetsuya Horita¹, Keita Sakamoto², Tamotsu Kamishima³ and Tatsuya Atsumi¹, ¹Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan, ²Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan, ³Hokkaido University, Faculty of Health Science, Sapporo, Japan
Background/Purpose: Magnetic Resonance Imaging (MRI) has been established as a useful modality to evaluate synovitis, bone edema, and bone erosion in patients with rheumatoid arthritis…
Abstract Number: 206 • 2014 ACR/ARHP Annual Meeting
Risk Factors for Increased Extrusion of the Meniscus Body in Subjects Free of Radiographic Knee Osteoarthritis: 6-Year MRI Data from the Osteoarthritis Initiative
Fan Zhang¹, Jaanika Kumm², Fredrik Svensson¹, Aleksandra Turkiewicz¹, Richard Frobell¹ and Martin Englund³, ¹Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Radiology, Tartu University, Tartu, Estonia, ³Department of Orthopedics, Lund University, Lund, Sweden
Background/Purpose Meniscal body extrusion on knee MRI is strongly associated with the development and progression of knee osteoarthritis (OA). However, there is very limited evidence…
Abstract Number: 2790 • 2014 ACR/ARHP Annual Meeting
CMR with Quantitative T2 Mapping in Patients with Active SLE
Stacy P. Ardoin¹, Wael N. Jarjour², Subha V. Raman², Amanda Kibler² and Tam Tran², ¹Pediatric & Adult Rheumatology, Ohio State University College of Medicine, Columbus, OH, ²Ohio State University, Columbus, OH
Background/Purpose: Cardiovascular (CV) disease is an important cause of morbidity in systemic lupus erythematosus (SLE) . Myocarditis is considered an uncommon complication of SLE…
Abstract Number: 1578 • 2014 ACR/ARHP Annual Meeting
Abatacept Improves Synovitis As Assessed By Magnetic Resonance Imaging (MRI) in Psoriatic Arthritis – Preliminary Analysis from a Single Centre, Placebo-Controlled, Crossover Study
Agnes Szentpetery¹, Eric J. Heffernan², Muhammad Haroon³, Phil Gallagher¹, Anne-Marie Baker¹, Martina Cooney¹ and Oliver FitzGerald¹, ¹Rheumatology, St. Vincent's University Hospital, Dublin, Ireland, ²Radiology, St. Vincent's University Hospital, Dublin, Ireland, ³Newmarket On Fergus, Cork University Hospital, Cork, Ireland
Background/Purpose Abatacept is a soluble, fully human fusion protein which selectively inhibits T-cell activation via the CD80/CD86:CD28 co-stimulation pathway and decreases serum levels of inflammatory…
Abstract Number: 1180 • 2014 ACR/ARHP Annual Meeting
Dynamic Magnetic Resonance Imaging in the Assessment of the Response to Certolizumab Pegol in Rheumatoid Arthritis Patients: Results from a Phase IIIb Randomized Study
Mikkel Østergaard¹, Mette Bjørndal Axelsen², Lennart T.H. Jacobsson³, Christopher Schaufelberger³, Michael Sejer Hansen⁴, Johannes W.J. Bijlsma⁵, Anna Dudek⁶, Maria Rell-Bakalarska⁷, Fabienne Staelens⁸, Robert Haake⁹, Britt Sundman-Engberg¹⁰ and Henning Bliddal¹¹, ¹Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Glostrup Hospital, Glostrup, Denmark, ²Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Glostrup, Denmark, ³Department of Rheumatology and Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, ⁴Department of Rheumatology, Gentofte Hospital, Copenhagen, Denmark, ⁵Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ⁶Medica Pro Familia, Warsaw, Poland, ⁷Rheuma Medicus, Warsaw, Poland, ⁸UCB Pharma, Brussels, Belgium, ⁹UCB Pharma, Raleigh, NC, ¹⁰UCB Pharma, Stockholm, Sweden, ¹¹The Parker Institute, Department of Rheumatology, Frederiksberg, Denmark
Background/Purpose Magnetic resonance imaging (MRI) can detect early joint inflammation with high sensitivity, without use of radiation. The MARVELOUS study (NCT01235598), using the OMERACT RA…
Abstract Number: 205 • 2014 ACR/ARHP Annual Meeting
Natural History and Clinical Significance of Meniscal Tears over 8 Years in a Largely Non-Osteoarthritic Cohort
Hussain Ijaz Khan¹, Dawn Aitken¹, Changhai Ding², Leigh Blizzard³, Jean-Pierre Pelletier⁴, Johanne Martel-Pelletier⁴, Flavia Cicutinni⁵ and Graeme Jones², ¹Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia, ³Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ⁴Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ⁵Department of Epidemiology and Preventive Medicine, Monash University, Monash University, Melbourne, Australia, Melbourne, Australia
Background/Purpose: Meniscal tears are a key player in knee osteoarthritis (OA) and family history of the disease has been shown to play an important role.…
Abstract Number: 2601 • 2014 ACR/ARHP Annual Meeting
Serum Biomarkers Associated with Changes in ASDAS and MRI Following Treatment of Ankylosing Spondylitis with Golimumab
Robert D. Inman¹, Xenofon Baraliakos², Kay-Geert A. Hermann³, Jürgen Braun⁴, Atul A. Deodhar⁵, Désirée van der Heijde⁶, Stephen Xu⁷ and Benjamin Hsu⁷, ¹Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ³Radiology, Charité Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Oregon Health and Sciences University, Portland, OR, ⁶Leiden University Medical Center, Leiden, Netherlands, ⁷Janssen Research & Development, LLC., Spring House, PA
Background/Purpose Serum biomarkers that can predict subsequent clinical or imaging outcomes would aid decision-making in the management of ankylosing spondylitis (AS). Using data from the…
Abstract Number: 1581 • 2014 ACR/ARHP Annual Meeting
Inflammatory Back Pain in Psoriasis and Psoriatic Arthritis Is Suggestive of Undiagnosed Spondyloarthropathies
Majed Khraishi¹, Heather Jones^2,3 and Annette Szumski⁴, ¹Clinical Professor of Medicine (Rheumatology), Memorial University of Newfoundland, St. John's, NF, Canada, ²Inflammation & Immunology, Pfizer Inc., Collegeville, PA, ³Pfizer Inc., Collegeville, PA, ⁴Specialty Care, Pfizer Inc., Collegeville, PA
Background/Purpose: Patients with psoriasis (Ps) and/or psoriatic arthritis (PsA) may have clinical features suggestive of axial skeletal abnormalities and should be assessed for the presence…
Abstract Number: 1024 • 2014 ACR/ARHP Annual Meeting
Racial Differences in Biochemical Knee Cartilage Composition Between African American and Caucasian American Women with MR-Based T2 Relaxation Time Measurements – Data from the Osteoarthritis Initiative
Martin Kretzschmar¹, Ursula Heilmeier², Aihong Yu³, Gabby B. Joseph⁴, Felix Liu⁵, Hans Liebl³, Charles E. McChulloch⁶, Michael C. Nevitt⁷, Nancy E. Lane⁸ and Thomas M Link⁹, ¹Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging,, University of California, San Francisco, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ³Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, ⁴Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San FRancisco, CA, ⁵University of California at San Francisco, San Francisco, CA, ⁶Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, ⁷Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁸Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ⁹Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose: To determine whether knee cartilage composition differs between African-American and matched Caucasian-American women at risk for Osteoarthitis (OA) using in-vivo 3T MRI T2 relaxation…
Abstract Number: 215 • 2014 ACR/ARHP Annual Meeting
External Hip Adduction Moment and Progression of Medial Tibiofemoral Cartilage Damage and Bone Marrow Lesions in Persons with Knee Osteoarthritis
Kirsten Moisio¹, Alison H. Chang², Ali Guermazi³, Joan S. Chmiel¹, Orit Almagor¹, Pottumarthi Prasad¹, Yunhui Zhang¹, Karen W. Hayes¹, Laura Belisle¹, Jamie Rayahin⁴ and Leena Sharma¹, ¹Northwestern University, Chicago, IL, ²Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL, ³Radiology, Boston University School of Medicine, Boston, MA, ⁴University of Illinois at Chicago, Chicago, IL
Background/Purpose Gait mechanics at the hip may affect medial joint loading at the knee in persons with knee OA. Greater external hip adduction moment (reflecting…
Abstract Number: 2597 • 2014 ACR/ARHP Annual Meeting
Impact of Repeating Imaging of the Sacro-Iliac Joints over One Year on the Classification According the ASAS Axial Spa Criteria of Patients
Pauline Bakker¹, Manouk de Hooge¹, Rosaline van den Berg², Floris van Gaalen², Monique Reijnierse¹, T.W.J. Huizinga¹ and Désirée van der Heijde³, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: It is known that in axial spondyloarthritis (axSpA) inflammatory lesions on MRI of the SI joints (MRI-SI) can change over time. The usefulness of…

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