Abstracts tagged "MRI"

Abstract Number: 714 • 2015 ACR/ARHP Annual Meeting
Baseline MRI and CRP As Predictors of Response to Etanercept in the Management of Patients with Non-Radiographic Axial Spondyloarthritis (nr-axSpA)
Matthew A. Brown¹, Paul A. Bird², Philip C. Robinson³, Philip J. Mease⁴, Filip van Den Bosch⁵, Christine Surian⁶, Zirke Wiid⁶, Heather Jones⁷, Annette Szumski⁸ and Lisa Marshall⁷, ¹Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, ²University of New South Wales, Sydney, Australia, ³University of Queensland & Royal Brisbane and Women's Hospital, Brisbane, Australia, ⁴Rheumatology Research, Swedish Medical Center, Seattle, WA, ⁵Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁶Pfizer Australia, Sydney, Australia, ⁷Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, ⁸Department of Biostatistics, Pfizer, Collegeville, PA
Background/Purpose: Treatment with tumor necrosis factor α (TNFα) inhibitors has been shown to be effective in improving disease activity and functional capacity in patients with…
Abstract Number: 1727 • 2015 ACR/ARHP Annual Meeting
MRI Vertebral Corner Inflammation Followed By Fat Deposition Is the Strongest Contributor to the Development of New Bone at the Same Vertebral Corner: A Multi-Level Longitudinal Analysis in Patients with Ankylosing Spondylitis
Pedro Machado¹, Xenofon Baraliakos², Désirée van der Heijde³, Juergen Braun² and Robert Landewé⁴, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: Syndesmophyte formation in ankylosing spondylitis (AS) is still insufficiently understood. Previous studies have suggested an association between MRI vertebral corner inflammation (VCI) and vertebral…
Abstract Number: 3255 • 2015 ACR/ARHP Annual Meeting
Brain White Matter Integrity: A Future Biomarker for Rheumatoid Arthritis Related Fatigue?
Neil Basu¹, Marayam Alsyedalhashem², Mariella D'Allesandro³, Alison D. Murray², Daniel J. Clauw⁴ and Gordon D. Waiter², ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, United Kingdom, ³Muscloskeletal Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ⁴Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Fatigue is a major burden among patients with rheumatoid arthritis (RA). The identification of reliable biomarkers would greatly enhance research in this challenging field. …
Abstract Number: 950 • 2015 ACR/ARHP Annual Meeting
In a Two-Year Double-Blind Randomized Controlled Multicenter Study, Chondroitin Sulfate Was Significantly Superior to Celecoxib at Reducing Cartilage Loss with Similar Efficacy at Reducing Disease Symptoms in Knee Osteoarthritis Patients
Jean-Pierre Pelletier¹, Jean Pierre Raynauld², André Beaulieu³, Louis Bessette⁴, Frédéric Morin⁵, Artur J Fernandes⁶, François Abram⁷, Marc Dorais⁸ and Johanne Martel-Pelletier⁹, ¹Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, ²Osteoarthritis Research Unit, CRCHUM, Montreal, Montreal, QC, Canada, ³Centre de rhumatologie St-Louis, St. Louis, QC, Canada, ⁴Groupe de Recherche en Rhumatologie et Maladies Osseuses, Quebec, Quebec, QC, Canada, ⁵Centre de Recherche Musculo-squelettique, Trois-Rivières, Trois-Rivières, QC, Canada, ⁶Centre de Recherche Musculo-squelettique, Trois-Rivières, 6Rheumatology Division, Sherbrooke, Sherbrooke, QC, Canada, ⁷Medical Imaging Research & Development, ArthroLab Inc, Montreal, QC, Canada, ⁸StatSciences Inc., Montreal, Canada, Montreal, QC, Canada, ⁹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM),, Montreal, QC, Canada
Background/Purpose: In osteoarthritis (OA) treatment, although chondroitin sulfate (CS) was found in a number of studies using radiography to have a structure modifying effect, to…
Abstract Number: 1728 • 2015 ACR/ARHP Annual Meeting
Diffusion Weighted Imaging Is a Sensitive and Specific MRI Protocol for the Diagnosis and Assessment of Disease Severity in Ankylosing Spondylitis
Linda A. Bradbury¹, Kelly A. Hollis², Benoit Gautier², Sateesh Shankaranarayana³, Philip Robinson⁴, Nivene Saad³, Kim-Anh Lê Cao² and Matthew A. Brown¹, ¹The University of Queensland Diamantina Institute, Brisbane, Australia, ²University of Queensland Diamantina Institute, Brisbane, Australia, ³Princess Alexandra Hospital, Brisbane, Australia, ⁴Human Genetics Group, University of Queensland Diamantina Insititute, Brisbane, Australia
Background/Purpose: Diffusion weighted imaging (DWI) is an MRI protocol which assesses the random Brownian motion of water molecules in the tissue imaged; this motion is…
Abstract Number: 1006 • 2015 ACR/ARHP Annual Meeting
Incident Frequent Knee Pain Is Associated with Changes in Semi-Quantitative Imaging Biomarkers of Inflammation
C.Kent Kwoh¹, Michael J. Hannon², Tomoko Fujii³, Frank W Roemer⁴, Ali Guermazi⁵, David Hunter⁶, Felix Eckstein⁷ and Robert M. Boudreau⁸, ¹Department of Medicine, The University of Arizona Arthritis Center and Division of Rheumatology, Tucson, AZ, ²Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ³University of Pittsburgh, Pittsburgh, PA, ⁴Department of Radiology, Boston University School of Medicine, Boston, MA, ⁵Boston University School of Medicine, Boston, MA, ⁶Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁷Paracelsus Med Univ, Chondrometrics GmbH, Salzburg, Austria, ⁸Epidemiology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The cause of knee pain in osteoarthritis (OA) is multi-factorial, and there is increasing evidence of the role of inflammation in OA. The goal…
Abstract Number: 1729 • 2015 ACR/ARHP Annual Meeting
Predictors and Clinical Factors Associated with Change in Spinal Inflammation Assessed on MRI over 2 Years: Data from Tasmanian Ankylosing Spondylitis Study
Hussain Ijaz Khan¹, Louisa Chou², Patricia Lewis³, Anitra Wilson³, Janet Millner⁴ and Jane Zochling³, ¹Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ²Menzies Institute of Medical Research, University of Tasmania, Hobart, 7000, Australia, ³Menzies Institute of Medical Research, Hobart, Australia, ⁴Physiotherapy, Royal Hobart Hospital, Hobart, Australia
Background/Purpose: Ankylosing Spondylitis (AS) is debilitating disease affecting the axial skeleton which is often difficult to diagnose in early stages. Magnetic Resonance Imaging (MRI) is…
Abstract Number: 1007 • 2015 ACR/ARHP Annual Meeting
Change in Semi-Quantitative Imaging Biomarkers Predicts Knee Osteoarthritis Progression: Data from the Fnih OA Biomarkers Consortium
Jamie E. Collins¹, Elena Losina², Michael C. Nevitt³, Frank W. Roemer⁴, Ali Guermazi⁴, John A. Lynch⁵, Jeffrey N. Katz², C. Kent Kwoh⁶, Joanne M. Jordan⁷, Virginia Kraus⁸ and David Hunter⁹, ¹Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³University of California, San Francisco, San Francisco, CA, ⁴Boston University School of Medicine, Boston, MA, ⁵University of California San Francisco, San Francisco, CA, ⁶University of Arizona, Tucson, AZ, ⁷Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ⁸Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, ⁹University of Sydney, Sydney, Australia
Background/Purpose: Semi-quantitative scoring of magnetic resonance images (MRIs) is a valuable method for performing multi-feature assessment of the knee joint. The goal of this study…
Abstract Number: 1735 • 2015 ACR/ARHP Annual Meeting
Imaging and Clinical Factors Associated with Subchondral Sacroiliac Fatty Marrow in Axial Spondyloarthritis
Kavi Devulapalli¹, Xenofon Baraliakos², Daria Motamedi¹ and Lianne S. Gensler³, ¹Radiology, UCSF, SAN FRANCISCO, CA, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Magnetic resonance imaging (MR) plays an important role in the evaluation of inflammatory and structural changes in axial spondyloarthritis (axSpA) patients. Prior research suggests…
Abstract Number: 1011 • 2015 ACR/ARHP Annual Meeting
Impact of a Musculoskeletal “Mini-Residency” Continuing Professional Education Program on Knee MRI Orders By Primary Care Providers
Matthew Call^1,2, Andrea M. Barker³, Grant W. Cannon⁴, Phillip Lawrence⁵ and Michael J. Battistone⁶, ¹Rheumatology, University of Utah, Salt Lake City, UT, ²Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ³General Internal Medicine, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁴Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁵Pharmacology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁶Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT
Background/Purpose: The US Department of Veterans Affairs (VA) has developed a national continuing professional development program to train primary care providers (PCPs) in the evaluation…
Abstract Number: 1810 • 2015 ACR/ARHP Annual Meeting
A Five-Year Follow-up of Microvascular Dysfunction and Coronary Artery Disease in SLE: Results from a Community-Based Lupus Cohort
Vaneet K. Sandhu¹, Mariko L. Ishimori¹, Janet Wei², Louise Thomson², Daniel Berman², Jay Schapira², Noel Bairey Merz², Daniel Wallace³ and Michael Weisman³, ¹Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ²Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, ³Cedars-Sinai Medical Center, Los Angeles, CA
Background/Purpose: To investigate serial changes in the prevalence of coronary microvascular dysfunction and coronary artery disease (CAD) by cardiac imaging in a cohort of SLE…
Abstract Number: 2938 • 2014 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Placebo-Controlled, 16-Week Study of Subcutaneous Golimumab in Patients with Active Nonradiographic Axial Spondyloarthritis
J Sieper¹, D van der Heijde², M Dougados³, Walter P. Maksymowych⁴, J Boice⁵, G Bergman⁵, S Curtis⁵, A Tzontcheva⁵, S Huyck⁵ and HH Weng⁵, ¹University Clinic Benjamin Franklin, Berlin, Germany, ²Leiden University Medical Center, Leiden, Netherlands, ³Paris-Descartes University, Paris, France, ⁴Department of Medicine, University of Alberta, Alberta, AK, ⁵Merck & Co., Inc., Whitehouse Station, NJ
Background/Purpose Axial spondyloarthritis (axSpA), including ankylosing spondylitis and nonradiographic axial SpA (nr-axSpA), is a chronic inflammatory disease marked by back pain and progressive spinal stiffness.…
Abstract Number: 1688 • 2014 ACR/ARHP Annual Meeting
Early Detection of Left Ventricular Morphological, Functional Abnormalities and Myocardial Characteristics in Systemic Sclerosis without Cardiac Symptoms Using Cardiac Magnetic Resonance Imaging: A Preliminary Report
Kaita Sugiyama¹, Hitomi Kobayashi², Yasuyuki Kobayashi³, Yosuke Nagasawa⁴, Natsumi Ikumi², Takamasa Nozaki⁴, Hirotake Inomata², Hidetaka Shiraiwa², Hiromi Karasawa², Noboru Kitamura⁴, Mitsuhiro Iwata⁴, Yoshihiro Matsukawa² and Masami Takei⁴, ¹Nihon University School of Medicine, Tokyo, Japan, ²Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan
Background/Purpose Systemic sclerosis (SSc) is associated with an increased prevalence of cardiac involvement despite often being clinically silent. Cardiac involvement is a major factor in…
Abstract Number: 1179 • 2014 ACR/ARHP Annual Meeting
Efficacy of Tocilizumab in Patients with Rheumatoid Arthritis: Sequential Evaluation Using Whole-Body Magnetic Resonance Imaging
Michihito Kono¹, Shinsuke Yasuda¹, Kazumasa Ohmura¹, Tomoko Fukui¹, Sanae Shimamura¹, Ikuma Nakagawa¹, Atsushi Noguchi¹, Haruki Shida¹, Toshiyuki Watanabe¹, Yuka Shimizu¹, Takashi Kurita¹, Kenji Oku¹, Toshiyuki Bohgaki¹, Olga Amengual¹, Tetsuya Horita¹, Keita Sakamoto², Tamotsu Kamishima³ and Tatsuya Atsumi¹, ¹Division of Rheumatology, Endocrinology and Nephrology, Hokkaido University Graduate School of Medicine, Sapporo, Japan, ²Department of Radiation Medicine, Hokkaido University Graduate School of Medicine, Sapporo, Japan, ³Hokkaido University, Faculty of Health Science, Sapporo, Japan
Background/Purpose: Magnetic Resonance Imaging (MRI) has been established as a useful modality to evaluate synovitis, bone edema, and bone erosion in patients with rheumatoid arthritis…
Abstract Number: 206 • 2014 ACR/ARHP Annual Meeting
Risk Factors for Increased Extrusion of the Meniscus Body in Subjects Free of Radiographic Knee Osteoarthritis: 6-Year MRI Data from the Osteoarthritis Initiative
Fan Zhang¹, Jaanika Kumm², Fredrik Svensson¹, Aleksandra Turkiewicz¹, Richard Frobell¹ and Martin Englund³, ¹Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Radiology, Tartu University, Tartu, Estonia, ³Department of Orthopedics, Lund University, Lund, Sweden
Background/Purpose Meniscal body extrusion on knee MRI is strongly associated with the development and progression of knee osteoarthritis (OA). However, there is very limited evidence…

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