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Abstracts tagged "mouse model and spondylarthropathy"

  • Abstract Number: 1576 • ACR/ARHP Annual Meeting 2017

    IL-23 Promotes Fecal Microbiota Dysbiosis Associated with Susceptibility to Spondyloarthritis and Ileitis in ZAP-70 Mutant SKG Mice

    Linda Rehaume1, Nicholas Matigian1, Kate Ormerod2, Alicia Kang1, Richard Linedale1, Olga Zbarskaya1, Kristine Kikly3, Joshua Daly2, Nancy Lachner2, Philip Hugenholtz2, Mark Morrison1, Kim-Anh LĂȘ Cao4 and Ranjeny Thomas1, 1The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia, 2Australian Centre for Ecogenomics, The University of Queensland, Brisbane, Australia, 3Biotechnology Discovery Research, Eli Lilly and Co, Indianapolis, IN, 4School of Mathematics and Statistics, Centre for Systems Genomics, The University of Melbourne, Melbourne, Australia

    Background/Purpose: Identification of disease-associated or protective bacteria may elucidate new biomarkers or probiotic supplements for people suffering from SpA, or for people at-risk of disease…

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