Abstracts tagged "mouse model and neuropsychiatric disorders"

Abstract Number: 82 • 2019 ACR/ARP Annual Meeting
Rab4A Increases Mitochondrial Oxidative Stress and Glutathione Disulfide Accumulation That Underlie Neurobehavioral Changes in Lupus-Prone Mice
Thomas Winans¹, Tamas Faludi ², Brandon Wyman ¹, Nick Huang ², Joshua Lewis ¹, Manuel Duarte ¹, Laurence Morel ³, Frank Middleton ² and Andras Perl ⁴, ¹Upstate Medical University, Syracuse, ²Upstate Medical University, Syracuse, NY, ³University of Florida, Gainesville, FL, ⁴SUNY Upstate Medical University, Syracuse, NY
Background/Purpose: Background/Purpose The human GTPase HRES-1/Rab4 has been identified as a susceptibility locus for systemic lupus erythematosus (SLE) and is overexpressed in T cells of…

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Abstracts tagged "mouse model and neuropsychiatric disorders"

Rab4A Increases Mitochondrial Oxidative Stress and Glutathione Disulfide Accumulation That Underlie Neurobehavioral Changes in Lupus-Prone Mice