Abstracts tagged "Mortality"

Abstract Number: 2213 • ACR Convergence 2024
Microvascular and Macrovascular Endothelial Dysfunction in Rheumatoid Arthritis
Vanshika Sabharwal, and Dr Ashit syngle and Dr Inderjeet Verma, MMDU, Mullana, Ambala India and Healing Touch city clinic, Chandigarh, India, Chandigarh, Chandigarh, India
Background/Purpose: RA is a chronic inflammatory disease associated with an excessive premature cardiovascular morbidity and mortality. Endothelial dysfunction is a significant contributor to CVD in…
Abstract Number: 2589 • ACR Convergence 2024
A Nationwide Analysis of Risk of Acute Coronary Syndrome in RA Patients with Interstitial Lung Disease
Omair Khan¹, Azka Naeem², Kundan Jana², Syed Mujtaba Baqir², Tharun Shyam² and Saumya Nanda², ¹Maimonides Medical Center, Council Bluffs, IA, ²Maimonides Medical Center, Brooklyn, NY
Background/Purpose: Rheumatoid Arthritis (RA) and Interstitial Lung Disease (ILD) are systemic inflammatory conditions that independently increase the risk of Acute Coronary Syndrome (ACS). However, there…
Abstract Number: 0651 • ACR Convergence 2024
Renal Survival and Mortality in Patients with Proliferative and Membranous Lupus Nephritis
Jung-Min Shin¹, Jiyoung Lee², Hye-Soon Lee³, Sang-Cheol Bae³ and So-Young Bang³, ¹Department of Rheumatology, Nowon Eulji Medical Center, Seoul, Republic of Korea, ²Hanyang University Institute for Rheumatology Research, Seoul, Republic of Korea, ³Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea
Background/Purpose: Lupus nephritis (LN) affects approximately 50% of patients and is a major determinant in the survival and prognosis of patients with systemic lupus erythematosus…
Abstract Number: 1149 • ACR Convergence 2024
Cause-Specific Proportionate Mortality Trends in Idiopathic Inflammatory Myopathies
Ansaam Daoud¹, Muhammad Shamim², Loai Dweik³ and Haseeb Chaudhary⁴, ¹Case Western Reserve University/University Hospitals, Akron, OH, ²University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, ³Cleveland Clinic Akron General Internal Medicine, Akron, OH, ⁴Case Western Reserve University, Westlake, OH
Background/Purpose: Idiopathic inflammatory myopathies (IIM) are associated with increased morbidity, mortality, and economic health burden compared to the general population despite advancements in overall disease management.…
Abstract Number: 2227 • ACR Convergence 2024
Worrisome Mortality Trends over 20 Years Among Patients with Underlying Ischemic Heart Disease and Rheumatoid Arthritis
Yukthi Mudiam¹ and Shreyas Singireddy², ¹Apollo Institute of Medical Sciences and Research, Richmond, TX, ²Department of Cardiology, University of Illinois College of Medicine, Peoria, IL
Background/Purpose: Ischemic heart disease (IHD) is one of the leading causes of death in the United States. Rheumatoid arthritis (RA), a chronic inflammatory condition affecting…
Abstract Number: 2673 • ACR Convergence 2024
Changes in Mortality Risk After Stopping Glucocorticosteroids – a Population-based Study in Rheumatoid Arthritis
Diane Lacaille¹, Coraline Danieli², Kasra Moolooghy¹ and Michal Abrahamowicz³, ¹Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada, ²Research Institute of McGill University Health Center (RI-MUHC), Montreal, QC, Canada, ³McGill University, Verdun, Canada
Background/Purpose: Glucocorticosteroid (GC) use is associated with increased mortality risk, especially from cardiovascular diseases (CVD) and infections, with dose and duration of use influencing risk.…
Abstract Number: 0685 • ACR Convergence 2024
KL-6 and IL-18 Biomarkers in Systemic Sclerosis-associated Interstitial Lung Disease: Enhancing Prognostic Insights into Early Detection, Progression, Lung Volume Changes,and Mortality Risk
cristiana sieiro santos¹, Miriam Retuerto², Laura Sierra², Sara Calleja Antolín², Elena Bollo de Miguel², Jose Ordas Martínez³, Paula Pérez García², Pedro Baenas², Clara Moriano Morales², Javier de la Calle Lorenzo² and Elvira Díez Álvarez⁴, ¹Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, ²Complejo Asistencial Universitario de León, León, Spain, ³Complejo Asistencial Universitario de Leon, Leon, ⁴Complejo Asistencial Universitario de León, Leon, Spain
Background/Purpose: Interstitial lung disease (ILD) is a leading cause of mortality in scleroderma, underscoring the critical demand for reliable biomarkers. KL-6 and IL-18, have been…
Abstract Number: 1327 • ACR Convergence 2024
Association of Rheumatoid Arthritis and Frailty Status with Mortality in Patients with Renal Cell Carcinoma
Sherwin Novin¹, Sarah Holt², Maya Swaminathan³, Jonathan Wright², John Gore², Kimme Hyrich⁴, Sizheng Zhao⁵, Jeffrey Sparks⁶, Una Makris⁷, Maria Suarez-Almazor⁸, Petros Grivas², Sarah Psutka² and Namrata Singh⁹, ¹University of Washington, Seattle, WA, ²University of Washington, Seattle, ³MultiCare, Newcastle, WA, ⁴Centre for Musculoskeletal Research, The University of Manchester, Manchester, United Kingdom, ⁵Centre for Musculoskeletal Research, The University of Manchester, Liverpool, United Kingdom, ⁶Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, Boston, MA, ⁷UT Southwestern Medical Center and Dallas VA, Dallas, TX, ⁸MD Anderson Cancer Center, Houston, TX, ⁹University of Washington, Bellevue, WA
Background/Purpose: Few studies have evaluated clinical outcomes and prognosis of patients with cancer with and without rheumatoid arthritis (RA). Renal cell carcinoma (RCC) is particularly…
Abstract Number: 2241 • ACR Convergence 2024
Associations Between Disease Activity, Physical Function and Anti-rheumatic Medications with All-cause Mortality in Rheumatoid Arthritis (RA): Data from a Canadian RA Registry
Mohammad Movahedi¹, Angela Cesta², Xiuying Li², Bindee Kuriya³, Sibel Aydin⁴, Ed Keystone⁵, Janet Pope⁶ and Claire Bombardier⁷, and OBRI investigators, ¹Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, ²UHN, Toronto, ON, Canada, ³University of Toronto - Toronto, Toronto, ON, Canada, ⁴Ottawa Hospital Research Institute, Ottawa, ON, Canada, ⁵Keystone Consulting Enterprises Inc., Toronto, ON, Canada, ⁶University of Western Ontario, London, ON, Canada, ⁷University of Toronto, Toronto, ON, Canada
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of hospitalizations and mortality due to RA itself, associated comorbidities, and treatment-related complications. The purpose…
Abstract Number: 0686 • ACR Convergence 2024
The Role of Inflammation in Systemic Sclerosis: CRP-Associated Phenotypes and Prognostic Implications
cristiana sieiro santos¹, Miriam Retuerto², Paula Pérez García², Jose Ordas Martínez³, Pedro Baenas², Clara Moriano Morales² and Elvira Díez Álvarez⁴, ¹Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, ²Complejo Asistencial Universitario de León, León, Spain, ³Complejo Asistencial Universitario de Leon, Leon, ⁴Complejo Asistencial Universitario de León, Leon, Spain
Background/Purpose: Systemic sclerosis (SSc) manifests through a diverse interplay of inflammatory, fibrotic, and vascular alterations, intricately entwined in its pathogenesis, which encompasses immune system dysregulation,…
Abstract Number: 1400 • ACR Convergence 2024
Disease Modifying Anti-rheumatic Drug Use and Association with Survival in Patients with Rheumatoid Arthritis and Newly Diagnosed Lung Cancer
Varun Nandakumar¹, Aaron Baraff², Alexander Peterson², Nicholas Smith³, Jennifer Barton⁴, Ann O'Hare², Christopher Li⁵, Noel Weiss³ and Namrata Singh⁶, ¹AIIMS, New Delhi, Delhi, India, ²VA PUGET SOUND SEATTLE, Seattle, WA, ³University of Washington, Seattle, WA, ⁴VA Portland Health Care System/OHSU, Portland, OR, ⁵University of Washington, Seattle, ⁶University of Washington, Bellevue, WA
Background/Purpose: Despite the significant therapeutic benefits of various disease modifying anti-rheumatic drugs (DMARDs) in RA, concerns remain regarding their safety, particularly their potential impact on…
Abstract Number: 2250 • ACR Convergence 2024
Cause Specific Mortality Differs in Rheumatoid Arthritis by Sex and Seropositivity
Elena Joerns¹, Ryan Lennon², Cynthia Crowson², Andrea Lopez-ruiz², Roslin Jose George², Vanessa Kronzer², John Davis² and Elena Myasoedova², ¹Mayo Clinic, Rochester, ²Mayo Clinic, Rochester, MN
Background/Purpose: Persons with rheumatoid arthritis (RA) have an increased risk of mortality compared to the general population. Seropositivity has been shown to be associated with…
Abstract Number: 0689 • ACR Convergence 2024
Arrhythmic Burden, Myocardial Markers, and Long-term Survival in Distinct Cardiac Magnetic Resonance Subsets of Systemic Sclerosis
Silvia Laura Bosello¹, Enrico De Lorenzis², Giacomo De Luca³, Antonio Tonutti⁴, veronica Batani⁵, Pier Giacomo Cerasuolo⁶, Gerlando Natalello⁷, Lucia Lanzo⁶, Gabriella Alonzi⁶, Silvia Fiore⁶, Stefano Di Murro⁶, Andrea Zoli⁶, Valentina Boni⁶, Riccardo Marano⁸, Francesca Augusta Gabrielli⁹, Francesco Del Galdo¹⁰, Dan Knight¹¹, Vivek Muthurangu¹¹, Christopher Denton¹², Maria De Santis⁴, Marco Matucci Cerinic⁵ and Maria Antonietta D'Agostino¹³, ¹Unit of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Catholic University of the Sacred Heart, Roma, Rome, Italy, ³Vita-Salute San Raffaele University & IRCCS San Raffaele Hospital, Milan, Milan, Italy, ⁴Rheumatology and Clinical Immunology, IRCCS Humanitas Research Hospital, Rozzano, Italy, ⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy, ⁶Division of Rheumatology, Catholic University of the Sacred Heart, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ⁷Division of Rheumatology - Catholic University of the Sacred Heart, Fondazione Policlinico Universitario Agostino Gemelli, Rome, Rome, Italy, ⁸Department of Diagnostic Imaging, Oncological Radiotherapy and Hematology, Diagnostic Imaging Area, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, Italy, ⁹Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ¹⁰University of Leeds, Leeds, United Kingdom, ¹¹UCL Department of Cardiac MRI, University College London (Royal Free Campus), London, United Kingdom, ¹²University College London, Northwood, United Kingdom, ¹³Division of Rheumatology, Fondazione Policlinico Universitario Agostino Gemelli IRCSS, Università Cattolica del Sacro Cuore, Rome, Italy
Background/Purpose: Cardiac involvement in Systemic Sclerosis (SSc) is widely recognized as heterogeneous and, when clinically evident, it is associated with a poor prognosis. Recently, five…
Abstract Number: 1522 • ACR Convergence 2024
Impact of Thrombocytopenia on In-hospital Mortality and Healthcare Resource Utilization in Patients with Systemic Lupus Erythematosus: An Analysis of the National Inpatient Sample Database 2020
Soziema Salia¹, Ufuoma Mamoh², Gilava Hedayati², Joseph Atarere³, Raymond Wadie⁴, Boniface Mensah³, Joan Morny⁵ and Indira Acharya⁶, ¹MedStar Union Memorial Hospital, Towson, MD, ²Medstar Union Memorial Hospital, Baltimore, MD, ³Department of Internal Medicine, MedStar Union Memorial Hospital, Baltimore, MD, ⁴Department of Internal Medicine, Cayuga Medical Center, Ithaca, NY, ⁵Piedmont Athens Regional Medical Center, Athens, GA, ⁶Medstar Internal Medicine Residency Program, Baltimore, MD
Background/Purpose: Thrombocytopenia is associated with Systemic Lupus Erythematosus (SLE) and occurs at various stages of the disease. It is reported in an estimated 10% to 40% of…
Abstract Number: 2297 • ACR Convergence 2024
Mortality and Its Predictor Variables in Patients with Sjögren Disease: Data from SjögrenSER-Pros Prospective Registry
Olga Rusinovich¹, Zulema Plaza², Mónica Fernández Castro³, José Rosas-Gómez de Salazar⁴, Victor Manuel Martinez Taboada⁵, Alejandro Olive⁶, Raúl Menor Almagro⁷, Belen Serrano Benavente⁸, Judit Font Urgelles⁹, Angel Garcia-Aparicio¹⁰, Sara Manrique-Arija¹¹, Jesus A García-Vadillo¹², Ruth Lopez Gonzalez¹³, Javier Narvaez-García¹⁴, Maria Beatriz Rodriguez¹⁵, Carlos Galisteo¹⁶, Jorge Gonzalez Martin¹⁷, Paloma Vela-Casasempere¹⁸, Cristina Bohorquez¹⁹, MARIA CELIA ERAUSQUIN ARRUABARRENA²⁰, MARIA BEATRIZ PAREDES ROMERO²¹, ELENA Aurrecoechea²², Sheila Melchor Diaz²³, José María Pego-Reigosa²⁴, Sergi Heredia Martin²⁵, Clara Moriano²⁶, Maria Angeles Blazquez Canamero²⁷, Paula Estrada-Alarcón²⁸, enrique Judez²⁹, Joaquin María Belzunegui:³⁰, Consuelo Ramos³¹, Marta de la Puerta³², Fernando Sánchez-Alonso³³ and Jose Luis Andreu³⁴, ¹Hospital Universitario Puerta de Hierro Majadahonda., Boadilla del Monte, Spain, ²Fundacion Española de Reumatología, Madrid, Spain, ³Hospital Universitario Puerta de Hierro Majadahonda., Madrid, Madrid, Spain, ⁴Hospital Marina Baixa, PALMA DE MALLORCA, Comunidad Valenciana, Spain, ⁵Facultad de Medicina. Universidad de Cantabria, Santander, Cantabria, Spain, ⁶Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain, ⁷Department of Rheumatology, Hospital Jerez de la Frontera, Jerez de la Frontera, Spain, ⁸Hospital Gregorio Marañón, Madrid, Madrid, Spain, ⁹Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ¹⁰Hospital Universitario de Toledo, Toledo, Spain, ¹¹Biomedical Research Institute of Malaga (IBIMA)-Bionand Platform, Department of Rheumatology, Regional University Hospital of Malaga, Malaga, Spain, ¹²H La Princesa, Madrid, Spain, ¹³Complejo Hospitalario de Zamora, Zamora, Castilla y Leon, Spain, ¹⁴Hospital Universitario de Bellvitge, Barcelona, Spain, ¹⁵H Universitario de Canarias, La Laguna- Tenerife, Canarias, Spain, ¹⁶Hospital Universitario Parc Taulí, Sabadell, Spain, ¹⁷H Madrid Norte SanChinarro, Madrid, Spain, ¹⁸Hospital General Universitario Alicante, Alicante, Spain, ¹⁹Hospital Universitario Príncipe de Asturias, Alcalá De Henares, Madrid, Spain, ²⁰Gob Canarias, Tenerife, Canarias, Spain, ²¹H Infanta Sofia, Madrid, Spain, ²²HOSPITAL SIERRALLANA, CANTABRIA, Spain, ²³12 de Octubre University Hospital, Madrid, Spain, ²⁴Galicia Health Service (SERGAS), Vigo, Spain, ²⁵Hospital de L’Hospitalet, Barcelona, Spain, ²⁶Hospital León, LEON, Spain, ²⁷Hospital Ramon y Cajal, Madrid, Madrid, Spain, ²⁸Hospital de San Juan Despí Moisès Broggi, Barcelona, Spain, ²⁹H de Albacete, Albacete, Spain, ³⁰H de Donostia, Donostia-San Sebasti, Spain, ³¹Hospital Universitario Virgen de Valme, Sevilla, Spain, ³²Spanish Society of Rheumatology, Madrid, Spain, ³³Sociedad Española de Reumatología, Madrid, Spain, ³⁴Hospital Universitario Puerta de Hierro Majadahonda., Majadahonda, Spain
Background/Purpose: It remains debated if patients with Sjögren´s disease (SjD) have a greater mortality risk. The objective of our study was to determine the magnitude…

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