Abstracts tagged "Morphea"

Abstract Number: 418 • 2015 ACR/ARHP Annual Meeting
Relationship of Race, Ethnicity, and Outcomes in Pediatric Localized Scleroderma: Possible Differences in Disease Activity
Kaveh Ardalan¹, Nicole Hershey¹, Jonathan Yabes², Kathryn S. Torok¹ and The CARRA Registry Investigators, ¹Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Pediatric localized scleroderma (LS) is an autoimmune skin and soft tissue disease that causes morbidity via progressive skin fibrosis and extracutaneous manifestations (ECMs), such…
Abstract Number: 1023 • 2015 ACR/ARHP Annual Meeting
Tumor Necrosis Factor-a (TNF-a) and Interferon Gamma Inducible Protein-10 (IP-10) As Predictors of Active Disease Status in Localized Scleroderma
Kathryn S. Torok¹, Jonathan Yabes², Qi Mi³, Christina Kelsey¹ and Kelsey Magee⁴, ¹Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ³Department of Sports Medicine and Nutrition, University of Pittsburgh, Pittsburgh, PA, ⁴Pediatrics, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Localized scleroderma has both inflammatory and fibrotic components contributing to its effect on the skin and underlying tissue. The extent and duration of…
Abstract Number: 3095 • 2015 ACR/ARHP Annual Meeting
Initial Results of a Pilot Juvenile Localized Scleroderma (jLS) Comparative Effectiveness Study
Suzanne C. Li¹, Kathryn S. Torok², Sandy D. Hong³, Polly J. Ferguson⁴, C. Egla Rabinovich⁵, Mara L Becker⁶, Fatma Dedeoglu⁷, Maria F. Ibarra⁸, Robert C. Fuhlbrigge^9,10, Katie G. Stewart¹¹, Marilynn G. Punaro¹¹, Thomas Mason II¹², Elena Pope¹³, Ronald Laxer¹⁴, Gloria C. Higgins^15,16 and Brian Feldman¹⁷, ¹Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, ²Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ³Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, ⁴Dept of Pediatrics--Rheum, University of Iowa, Iowa City, IA, ⁵Pediatric Rheumatology, Duke Univ Med Ctr, Durham, NC, ⁶Rheumatology, Children's Mercy Kansas City, Kansas City, MO, ⁷Rheumatology, Boston Children's Hospital, Boston, MA, ⁸Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, ⁹Program in Rheumatology, Division of Immunology, Boston Children’s Hospital, Boston, MA, ¹⁰Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ¹¹Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, ¹²Rheumatology, Mayo Clinic, Rochester, MN, ¹³Dermatology, Hospital for Sick Children, Toronto, ON, Canada, ¹⁴Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁵Pediatric Rheumatology OSU, Nationwide Childrens Hosp, Columbus, OH, ¹⁶Pediatric Rheumatology Ohio State University, Nationwide Childrens Hospital, Columbus, OH, ¹⁷Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Juvenile localized scleroderma (jLS) is a chronic inflammatory and fibrosing disease that causes severe morbidity, including growth defects, cosmetic deformities, seizures and arthropathy.…
Abstract Number: 1897 • 2014 ACR/ARHP Annual Meeting
Circulating T-Helper Cell- Associated Cytokines and Chemokines in Localized Scleroderma
Kathryn S. Torok¹, Katherine Kurzinski², Christina Kelsey³, Kelsey Magee⁴, Jonathan Yabes⁵, Abbe N. Vallejo⁶, Thomas A. Medsger Jr.⁷ and Carol A. Feghali-Bostwick⁸, ¹Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ³Pediatric Rheumatology, University of Pittsburgh/UPMC, Pittsburgh, PA, ⁴Pediatric Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁵Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ⁶Department of Immunology, University of Pittsburgh, Pittsburgh, PA, ⁷Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁸Medicine, Medical University of South Carolina, Charleston, SC
Background/Purpose: Localized scleroderma (LS) is an autoimmune disease of the skin and underlying tissues which results in disfigurement and orthopedic complications, especially when the onset…
Abstract Number: 1324 • 2014 ACR/ARHP Annual Meeting
Predictors of Disease Relapse in Juvenile Localized Scleroderma
Kathryn S. Torok¹, Katherine Kurzinski² and Christina Kelsey³, ¹Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ²Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA, ³Pediatric Rheumatology, University of Pittsburgh/UPMC, Pittsburgh, PA
Background/Purpose Localized scleroderma (LS) is an autoimmune disease characterized by inflammation of the skin and underlying tissue leading tissue damage including atrophy, dyspigmentation, and fibrosis. …
Abstract Number: 1321 • 2014 ACR/ARHP Annual Meeting
A Pilot Study to Evaluate the Feasibility of Conducting Juvenile Localized Scleroderma Comparative Effectiveness Treatment Studies
Suzanne C. Li¹, Kathryn S. Torok², Mara L Becker^3,4, Fatma Dedeoglu⁵, Polly J. Ferguson⁶, Robert C. Fuhlbrigge^7,8, Gloria C. Higgins⁹, Sandy D. Hong¹⁰, Maria F. Ibarra¹¹, Ronald Laxer¹², Thomas G. Mason II¹³, Elena Pope¹⁴, Marilynn G. Punaro¹⁵, C. Egla Rabinovich¹⁶, Katie G. Stewart¹⁵ and Brian Feldman¹⁷, ¹Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, ²Pediatric Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, ³Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁴Clinical Pharmacology and Rheumatology, Children's Mercy Hospital, Kansas City, MO, ⁵Rheumatology, Boston Children's Hospital, Boston, MA, ⁶Dept of Pediatrics--Rheum, University of Iowa Carver College of Medicine, Iowa City, IA, ⁷Department of Dermatology, Brigham and Women's Hospital, Boston, MA, ⁸Division of Immunology, Boston Children's Hospital, Boston, MA, ⁹Pediatric Rheumatology Ohio State University, Nationwide Childrens Hosp, Columbus, OH, ¹⁰Pediatrics-Rheumatology, U of Iowa Children's Hosp, Iowa City, IA, ¹¹Pediatric Rheumatolgy, Children's Mercy Hospital, Kansas City, MO, ¹²Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ¹³Rheumatology, Mayo Clinic Rochester, Rochester, MN, ¹⁴Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁵Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, ¹⁶Pediatric Rheumatology, Duke Univ Med Ctr, Durham, NC, ¹⁷Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose Juvenile localized scleroderma (jLS) often causes severe morbidity in the developing child, including growth defects and disfigurement. Optimal therapy is not known. The…
Abstract Number: 691 • 2013 ACR/ARHP Annual Meeting
Descriptive Review Of Morphea Subjects From a Single Cohort Center
Lesley Portugal¹, Muneera Naeem², Lakshmi N. Moorthy³ and Vivien M. Hsu⁴, ¹Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ, ²Medicine, Mountainside Hospital, Montclair, NJ, ³Pediatric Rheumatology, Robert Wood Johnson Medical School-Rutgers University, New Brunswick, NJ, ⁴Rheumatology, RWJ Med Schl Scleroderma Prog, New Brunswick, NJ
Descriptive review of Morphea subjects from a single cohort center Background/Purpose: Morphea, or localized scleroderma, is an idiopathic, rare fibrotic skin disorder that may result…

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