Abstracts tagged "morbidity and mortality"

Abstract Number: 223 • 2015 ACR/ARHP Annual Meeting
Increased Platelet Reactivity in Gout: A Potential Mechanism for Adverse Cardiovascular Events
Richard Conway¹, Claire-Louise Murphy², Anne Madigan², Patricia Kavanagh², Liz Geraghty², Laura Helbert², Kelly Stephens³, John J. Carey⁴, Eimear Dunne⁵, Dermot Kenny⁵ and Geraldine M. McCarthy⁶, ¹Rheumatology, Mater Misericordiae University Hospital, Dublin 2, Ireland, ²Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, ³Mater Misericordiae University Hospital, Clinical Research Center, Dublin, Ireland, ⁴Rheumatology, Galway University Hospitals, Galway, Ireland, ⁵Molecular and Cellular Therapeutics, RCSI, Dublin 2, Ireland, ⁶University College Dublin, Dublin, Ireland
Background/Purpose: Patients with inflammatory arthritis, including gout, have an increased risk of cardiovascular events and mortality. Increased platelet reactivity is a risk marker for cardiovascular…
Abstract Number: 826 • 2015 ACR/ARHP Annual Meeting
Systemic Sclerosis Inpatient Mortality Has Not Improved from 1995-2011. Results from a National Irish Audit of Scleroderma Co-Morbidities.
Len Harty¹, Deirdre Fitzgerald², Michael Henry², John Ryan³ and Sinead Harney³, ¹Cork University Hospital, Cork, Ireland, ²Respiratory, Cork University Hospital, Cork, Ireland, ³Rheumatology, Cork University Hospital, Cork, Ireland
Background/Purpose: Despite the advent of potent immunosuppressive and vasoactive therapies it is not clear that longevity of patients with systemic sclerosis (SSc) has improved. Therefore…
Abstract Number: 877 • 2015 ACR/ARHP Annual Meeting
Improved Survival in Granulomatosis with Polyangiitis: A Population-Based Study
Ju Ann¹, Hyon K. Choi², Sharan K. Rai³, Eric C. Sayre⁴ and J Antonio Avina-Zubieta^5,6, ¹Experimental Mediine, University of British Columbia, Richmond, BC, Canada, ²Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, ⁴Arthritis Research Canada, Richmond, BC, Canada, ⁵Arthritis Research Canada / University of British Columbia, Vancouver, BC, Canada, ⁶Medicine, University of British Columbia, Department of Medicine, Division of Rheumatology, Vancouver, BC, Canada
Background/Purpose: Granulomatosis with Polyangiitis (GPA) is associated with an increased risk of mortality. However, recent mortality trends in GPA are largely unknown, particularly in the…
Abstract Number: 909 • 2015 ACR/ARHP Annual Meeting
Smoking Behavior Changes after Rheumatoid Arthritis Diagnosis and Risk of Mortality during 36 Years of Prospective Follow-up
Jeffrey A. Sparks¹, Uyen Sa D.T. Nguyen^2,3, Shun-Chiao Chang^4,5, Yuqing Zhang⁶, Hyon Choi⁷ and Elizabeth W. Karlson⁴, ¹Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Clinical Epidemiology Research &Training Unit, Boston University School of Medicine, Boston, MA, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁶Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁷Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Smoking is a major preventable cause of death and cessation is recommended for the general population. However, it is unclear whether being diagnosis with…
Abstract Number: 912 • 2015 ACR/ARHP Annual Meeting
Secondary Preventive Pharmacotherapy and Longterm Outcomes Following Acute Coronary Events in Patients with Prevalent Rheumatoid Arthritis
Ängla Mantel¹, Marie Holmqvist¹, Tomas Jernberg², Solveig Wållberg-Jonsson³ and Johan Askling^4,5, ¹Dept of Medicine, Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, ²Section of Cardiology, Department of medicine, Karolinska University Hospital, Stockholm, Sweden, ³Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, ⁴Rheumatology Unit, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁵Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Suboptimal use of secondary preventive pharmacotherapies after acute coronary syndrome (ACS) in patients with rheumatoid arthritis (RA) has been suggested to contribute to an…
Abstract Number: 985 • 2015 ACR/ARHP Annual Meeting
Improved Survival in Systemic Lupus Erythematosus: A Population-Based Study
Kateryna Vostretsova¹, Sharan K. Rai², Eric C. Sayre³, Hyon K. Choi⁴, JM Esdaile⁵ and J Antonio Avina-Zubieta⁶, ¹Rheumatology, Arthritis Research Centre, Vancouver, BC, Canada, ²Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, ³Arthritis Research Canada, Richmond, BC, Canada, ⁴Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, ⁶Medicine, University of British Columbia, Department of Medicine, Division of Rheumatology, Vancouver, BC, Canada
Background/Purpose: Systemic Lupus Erythematosus (SLE) is associated with an increased risk of mortality. However, recent mortality trends of SLE are unknown, particularly at the general…
Abstract Number: 2413 • 2015 ACR/ARHP Annual Meeting
Contributors to Walking Disability in People with Osteoarthritis: Results from a Population-Based Cohort
Lauren King¹, Tetyana Kendzerska^1,2,3 and Gillian Hawker^1,2,3, ¹Department of Medicine, University of Toronto, Toronto, ON, Canada, ²Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, ³Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Osteoarthritis (OA) is associated with functional limitations, including difficulty walking. However, comorbid disease is common in people with OA and may also be associated…
Abstract Number: 1829 • 2014 ACR/ARHP Annual Meeting
Role of Fluorinated Steroids in Preventing the Progression of Anti-SSA/Ro Associated Isolated Congenital Heart Block to Disease Beyond the Conduction System
Ummara Shah¹, Amit Saxena¹, Sara Sahl², Deborah Friedman³, Jill P. Buyon¹ and Peter M. Izmirly², ¹Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ²Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ³Division of Pediatric Cardiology, New York Medical College, Valhalla, NY
Background/Purpose: The cardiac manifestations of neonatal lupus (cardiac NL) characteristically present as conduction disease. A major concern is the extension of injury beyond the AV…
Abstract Number: 1803 • 2014 ACR/ARHP Annual Meeting
Knee Osteoarthritis and All-Cause Mortality: The Wuchuan Osteoarthritis Study
Qiang Liu¹, Xu Tang Sr.², Jingbo Niu³, Xu Wu⁴, Yan Ke⁵, Jian Huang⁶, Rujun Li⁵, Hu Li⁵, Xin Zhi⁵, Kai Wang⁵, Zhengming Cao¹ and Jianhao Lin², ¹Arthritis Institute, People’s Hospital, Peking University, Beijing, China, ²Peking University Health Science Center, Beijing, China, ³Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, ⁴Peking University People's Hospital Arthritis Clinic & Research Center, Peking University Health Science Center, Beijing, China, ⁵Peking University People’s Hospital, Beijing, China, ⁶Orthopeadics, The Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China
Background/Purpose Several studies published recently found that knee osteoarthritis (OA) is associated with an increased mortality in Caucasians. While prevalence of knee OA is higher…
Abstract Number: 1431 • 2014 ACR/ARHP Annual Meeting
Influence of Radiographic Joint Damage in Mortality Risk in a Cohort of Rheumatoid Arthritis Patients: A 20 Years Survival Study
L. Rodriguez-Rodriguez^1,2, J. Ivorra-Cortes³, Lydia Abasolo^1,4, Leticia Leon^1,4, Oscar Fontsere⁵, B. Fernández-Gutiérrez^1,5 and Juan A Jover^1,4, ¹Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, ²Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, ³Rheumatology, University Hospital la Fe, Valencia, Spain, ⁴Rheumatology, Hospital Clinico San Carlos, Madrid, Spain, ⁵Rheumatology, Hospital Clínico San Carlos, Madrid, Spain
Background/Purpose Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased mortality and reduced life expectancy compared with the general population. This mortality gap…
Abstract Number: 1391 • 2014 ACR/ARHP Annual Meeting
Weight Loss and Risk of Death in Rheumatoid Arthritis
Joshua Baker¹, Erica Billig², Grant W. Cannon³, Liron Caplan⁴, Vikas Majithia⁵ and Ted R. Mikuls⁶, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁴Div of Rheumatology, Denver VA and Univ of Colorado School of Medicine, Aurora, CO, ⁵Div of Rheumatology, University of Mississippi Medical Center, Jackson, MS, ⁶Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE
Background/Purpose Low body mass index (BMI) has been linked to greater mortality among patients with Rheumatoid Arthritis (RA). Weight loss has also been associated with…
Abstract Number: 972 • 2014 ACR/ARHP Annual Meeting
Racial, Gender and Geographic Differences in Systemic Lupus Erythematous and Lupus Nephritis Mortality Rates in the Unites States, 1968-2010
Eric Y Yen¹, Magda Shaheen², Jennifer MP Woo³, Deborah K. McCurdy⁴ and Ram Raj Singh⁵, ¹Pediatrics/Rheumatology, UCLA Division of Pediatric Rheumatology, Los Angeles, CA, ²Charles R. Drew University of Medicine and Science, Los Angeles, CA, ³UCLA Division of Pediatric Rheumatology, Los Angeles, CA, ⁴Pediatric Rheumatology, UCLA Division of Pediatric Rheumatology, Los Angeles, CA, ⁵Medicine, UCLA Division of Rheumatology, Los Angeles, CA
Title: Racial, Gender and Geographic Differences in Systemic Lupus Erythematous and Lupus Nephritis Mortality Rates in the Unites States, 1968-2010Background/Purpose: Many epidemiologic studies of systemic…
Abstract Number: 817 • 2014 ACR/ARHP Annual Meeting
Mortality in a Large Cohort of Patients with Early Rheumatoid Arthritis That Were Treated-to-Target for 10 Years
I.M. Markusse¹, L. Dirven², J.H. van Groenendael³, K.H. Han⁴, H.K Ronday⁵, P.J.S.M. Kerstens⁶, W.F. Lems^7,8, T.W.J. Huizinga² and C.F. Allaart², ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Rheumatology, Fransiscus Hospital, Roosendaal, Netherlands, ⁴Rheumatology, MCRZ hospital, Rotterdam, Netherlands, ⁵Rheumatology, Haga Hospital, The Hague, Netherlands, ⁶Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ⁷Rheumatology, VU Medical Center, Amsterdam, Netherlands, ⁸Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands
Background/Purpose: Recent studies showed diverging results about mortality trends in patients with rheumatoid arthritis (RA). Our aim was to determine survival after 10 years of…
Abstract Number: 724 • 2014 ACR/ARHP Annual Meeting
Moderate Decline in Forced Vital Capacity is Associated with a Poor Outcome in Systemic Sclerosis Patients
Anna-Maria Hoffmann-Vold¹, Oyvind Midtvedt², Torhild Garen³, May Brit Lund⁴, T. Mogens Aalokken⁵, Jan Tore Gran² and Oyvind Molberg⁶, ¹Department of Rheumatology, Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ²Rheumatology, Oslo University Hospital, Oslo, Norway, ³Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ⁴Department of Respiratory Medicine, Oslo University Hospital Rikshopitalet, Oslo, Norway, ⁵Department of Radiology, Oslo University Hospital Rikshospitalet, Oslo, Norway, ⁶Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway
Background/Purpose: Interstitial lung disease (ILD) is a common manifestation in systemic sclerosis (SSc) and the leading cause of morbidity and mortality. Serial pulmonary function tests…
Abstract Number: 2997 • 2014 ACR/ARHP Annual Meeting
Development and External Validation of a Five-Year Mortality Risk Stratification Tool for Early Diffuse Systemic Sclerosis Patients
Robyn T. Domsic¹, Svetlana I. Nihtyanova², Mary Lucas³, Stephen R. Wisniewski⁴, Michael J. Fine⁵, C. Kent Kwoh⁶, Christopher P. Denton⁷ and Thomas A. Medsger Jr.⁸, ¹Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, ²Department of Rheumatology, Royal Free and University College Medical School, London, United Kingdom, ³Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ⁵General Medicine, University of Pittsburgh and Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare, Pittsburgh, PA, ⁶1501 N. Campbell Avenue, Room 8303, The University of Arizona Arthritis Center, Tucson, AZ, ⁷Centre for Rheumatology, Royal Free and University College Medical School, London, United Kingdom, ⁸Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose : Knowledge of mortality risk and predictors is important in systemic sclerosis (SSc) patient care and clinical trial design. There is no validated 5-year…

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