Abstracts tagged "morbidity and mortality"

Abstract Number: 909 • 2015 ACR/ARHP Annual Meeting
Smoking Behavior Changes after Rheumatoid Arthritis Diagnosis and Risk of Mortality during 36 Years of Prospective Follow-up
Jeffrey A. Sparks¹, Uyen Sa D.T. Nguyen^2,3, Shun-Chiao Chang^4,5, Yuqing Zhang⁶, Hyon Choi⁷ and Elizabeth W. Karlson⁴, ¹Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Clinical Epidemiology Research &Training Unit, Boston University School of Medicine, Boston, MA, ³Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ⁴Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁵Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁶Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁷Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Smoking is a major preventable cause of death and cessation is recommended for the general population. However, it is unclear whether being diagnosis with…
Abstract Number: 912 • 2015 ACR/ARHP Annual Meeting
Secondary Preventive Pharmacotherapy and Longterm Outcomes Following Acute Coronary Events in Patients with Prevalent Rheumatoid Arthritis
Ängla Mantel¹, Marie Holmqvist¹, Tomas Jernberg², Solveig Wållberg-Jonsson³ and Johan Askling^4,5, ¹Dept of Medicine, Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden, ²Section of Cardiology, Department of medicine, Karolinska University Hospital, Stockholm, Sweden, ³Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Umeå, Sweden, ⁴Rheumatology Unit, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁵Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Suboptimal use of secondary preventive pharmacotherapies after acute coronary syndrome (ACS) in patients with rheumatoid arthritis (RA) has been suggested to contribute to an…
Abstract Number: 985 • 2015 ACR/ARHP Annual Meeting
Improved Survival in Systemic Lupus Erythematosus: A Population-Based Study
Kateryna Vostretsova¹, Sharan K. Rai², Eric C. Sayre³, Hyon K. Choi⁴, JM Esdaile⁵ and J Antonio Avina-Zubieta⁶, ¹Rheumatology, Arthritis Research Centre, Vancouver, BC, Canada, ²Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, ³Arthritis Research Canada, Richmond, BC, Canada, ⁴Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵Rheumatology, Arthritis Research Canada, Richmond, BC, Canada, ⁶Medicine, University of British Columbia, Department of Medicine, Division of Rheumatology, Vancouver, BC, Canada
Background/Purpose: Systemic Lupus Erythematosus (SLE) is associated with an increased risk of mortality. However, recent mortality trends of SLE are unknown, particularly at the general…
Abstract Number: 2413 • 2015 ACR/ARHP Annual Meeting
Contributors to Walking Disability in People with Osteoarthritis: Results from a Population-Based Cohort
Lauren King¹, Tetyana Kendzerska^1,2,3 and Gillian Hawker^1,2,3, ¹Department of Medicine, University of Toronto, Toronto, ON, Canada, ²Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, ³Women's College Research Institute, Women's College Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Osteoarthritis (OA) is associated with functional limitations, including difficulty walking. However, comorbid disease is common in people with OA and may also be associated…
Abstract Number: 2582 • 2015 ACR/ARHP Annual Meeting
Increased Morbidity and Mortality in Female Versus Male Tumor Necrosis Factor-Transgenic Mice
Richard Bell¹, Ronald Wood², Joe Chakkalakal³, Christopher T. Ritchlin⁴, Edward Schwarz⁵ and Homaira Rahimi⁶, ¹Pathology, University of Rochester, Rochester, NY, ²University of Rochester, Rochester, NY, ³Orthopaedics, University of Rochester, Rochester, NY, ⁴Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁵Orthopedeatrics, University of Rochester, Rochester, NY, ⁶Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY
Background/Purpose: Rheumatoid arthritis (RA) is a chronic debilitating condition with a 2-3 fold greater prevalence in women than men. Additionally, women have worse disease outcomes…
Abstract Number: 3240 • 2015 ACR/ARHP Annual Meeting
Improved Survival in Rheumatoid Arthritis: A General Population-Based Study
Na Lu^1,2, Hyon K. Choi³, Sara R. Schoenfeld³, Christine Peloquin⁴, Maureen Dubreuil⁵, Sharan K. Rai⁶, J Antonio Avina-Zubieta⁷ and Yuqing Zhang⁸, ¹Division of Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁵Rheumatology, Boston VA HealthCare System, Boston, MA, ⁶Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, ⁷Arthritis Research Canada / University of British Columbia, Vancouver, BC, Canada, ⁸BUSM, Boston, MA
Background/Purpose: All-cause mortality in UK has been decline by almost 20% over the past two decades. While rheumatoid arthritis (RA) is associated with an increased…
Abstract Number: 41 • 2015 ACR/ARHP Annual Meeting
Trends in Non-Cardiovascular Mortality in Patients with Incident Rheumatoid Arthritis: Is There Room for Improvement?
Elena Myasoedova¹, Cynthia S. Crowson², Eric L. Matteson³, John M. Davis III⁴ and Sherine E. Gabriel⁵, ¹Internal Medicine and Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Rheumatology, Mayo Clinic, Rochester, MN, ⁴Division of Rheumatology, Mayo Clinic, Rochester, MN, ⁵Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ
Background/Purpose: Rheumatoid arthritis (RA) is associated with increased all-cause and cause-specific mortality, including mortality from cardiovascular (CV) disease, respiratory causes, infections and malignancy. Evidence of…
Abstract Number: 2997 • 2014 ACR/ARHP Annual Meeting
Development and External Validation of a Five-Year Mortality Risk Stratification Tool for Early Diffuse Systemic Sclerosis Patients
Robyn T. Domsic¹, Svetlana I. Nihtyanova², Mary Lucas³, Stephen R. Wisniewski⁴, Michael J. Fine⁵, C. Kent Kwoh⁶, Christopher P. Denton⁷ and Thomas A. Medsger Jr.⁸, ¹Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA, ²Department of Rheumatology, Royal Free and University College Medical School, London, United Kingdom, ³Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ⁵General Medicine, University of Pittsburgh and Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare, Pittsburgh, PA, ⁶1501 N. Campbell Avenue, Room 8303, The University of Arizona Arthritis Center, Tucson, AZ, ⁷Centre for Rheumatology, Royal Free and University College Medical School, London, United Kingdom, ⁸Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose : Knowledge of mortality risk and predictors is important in systemic sclerosis (SSc) patient care and clinical trial design. There is no validated 5-year…
Abstract Number: 3000 • 2014 ACR/ARHP Annual Meeting
Comparison of Systemic Sclerosis Subsets As Predictors of Mortality and Morbidity
Hebah Alhajeri¹, Marie Hudson^2,3, Canadian Scleroderma Research Group CSRG⁴ and Murray Baron⁵, ¹Rheumatology, McGill University, Montreal, QC, Canada, ²Rheumatology, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada, ³Division of Rheumatology, McGill University, Montreal, QC, Canada, ⁴McGill University, Montreal, QC, Canada, ⁵Pavillion A, Rm 216, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada
Background/Purpose: Identifying systemic sclerosis (SSc) subsets that predict mortality and morbidity could provide useful prognostic information. We undertook this study to compare the predictive ability…
Abstract Number: 2941 • 2014 ACR/ARHP Annual Meeting
Physical Function Is Independently Associated with Mortality Among Individuals with Knee and/or Hip OA: The Johnston County Osteoarthritis Project
Rebecca J. Cleveland¹, Todd Schwartz¹, Jordan B. Renner², Joanne M. Jordan³ and Leigh F. Callahan⁴, ¹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²University of North Carolina Department of Radiology, Chapel Hill, NC, ³University of North Carolina Dept of Epidemiology, Chapel Hill, NC, ⁴Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC
Background/Purpose Declining physical function (PF) is a common consequence of osteoarthritis (OA), and poor PF is associated with death. It is possible that the resulting…
Abstract Number: 2620 • 2014 ACR/ARHP Annual Meeting
Mortality and Survival in Systemic Lupus Erythematosus Patients: Trends in a Spanish Cohort from 1985 to 2013
Sergi Heredia¹, Javier Narváez², Andrea Zacarias¹, Milagros Ricse¹, Gloria Albert¹, Eulalia Armengol¹, Helena Borrell¹, Olga Capdevila³, Francesca Mitjavila³, Toni Rozadilla¹, Xavier Juanola⁴ and Joan Miquel Nolla¹, ¹Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ²Rheumatology, Hospital Universitario de Bellvitge. Barcelona. Spain, Barcelona, Spain, ³Internal Medicine, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁴Rheumatology, University Hospital Bellvitge, Barcelona, Spain
Background/Purpose: To study the mortality, survival and causes of death in a Spanish cohort of patients with systemic lupus erythematosus (SLE) over a 28-year period…
Abstract Number: 2188 • 2014 ACR/ARHP Annual Meeting
Incidence and Mortality of Relapsing Polychondritis in the United Kingdom: A Population-Based Cohort Study
Nisha Hazra¹, Alex Dregan¹, Judith Charlton¹, Martin C Gulliford¹ and David P. D'Cruz², ¹Division of Primary Care and Public Health Research, King's College London, London, United Kingdom, ²Louise Coote Lupus Unit, Guy's and St Thomas' Hospital, London, United Kingdom
Background/Purpose: To estimate the incidence, prevalence and mortality of Relapsing Polychondritis (RP), and to describe the clinical features of RP, in a large population. Methods:…
Abstract Number: 2038 • 2014 ACR/ARHP Annual Meeting
Respiratory Cause Mortality Was Significantly Predicted By Incident Rheumatoid Arthritis (RA) and Higher Pre-RA Levels (0.50+ SD) of Soluble Interleukin-2 Receptor Alpha (sIL-2Rá): Results of a 21-Year Community-Based Cohort Survival Analysis
Alfonse T. Masi¹, Azeem Rehman¹, Huaping Wang¹ and Jean Aldag², ¹Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, ²Medicine, University of Illinois College of Medicince at Peoria, retired, Peoria, IL
Background/Purpose: Interstitial lung disease (ILD) mortality is reported to be increased in RA (Bongartz T et al. A&R 2010; 62: 1583-91). However, non-malignant respiratory mortality…
Abstract Number: 1829 • 2014 ACR/ARHP Annual Meeting
Role of Fluorinated Steroids in Preventing the Progression of Anti-SSA/Ro Associated Isolated Congenital Heart Block to Disease Beyond the Conduction System
Ummara Shah¹, Amit Saxena¹, Sara Sahl², Deborah Friedman³, Jill P. Buyon¹ and Peter M. Izmirly², ¹Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ²Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ³Division of Pediatric Cardiology, New York Medical College, Valhalla, NY
Background/Purpose: The cardiac manifestations of neonatal lupus (cardiac NL) characteristically present as conduction disease. A major concern is the extension of injury beyond the AV…
Abstract Number: 1803 • 2014 ACR/ARHP Annual Meeting
Knee Osteoarthritis and All-Cause Mortality: The Wuchuan Osteoarthritis Study
Qiang Liu¹, Xu Tang Sr.², Jingbo Niu³, Xu Wu⁴, Yan Ke⁵, Jian Huang⁶, Rujun Li⁵, Hu Li⁵, Xin Zhi⁵, Kai Wang⁵, Zhengming Cao¹ and Jianhao Lin², ¹Arthritis Institute, People’s Hospital, Peking University, Beijing, China, ²Peking University Health Science Center, Beijing, China, ³Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, ⁴Peking University People's Hospital Arthritis Clinic & Research Center, Peking University Health Science Center, Beijing, China, ⁵Peking University People’s Hospital, Beijing, China, ⁶Orthopeadics, The Second Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China
Background/Purpose Several studies published recently found that knee osteoarthritis (OA) is associated with an increased mortality in Caucasians. While prevalence of knee OA is higher…

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