Abstracts tagged "morbidity and mortality and rheumatoid arthritis (RA)"

Abstract Number: 824 • 2014 ACR/ARHP Annual Meeting
Impact of Oral Glucocorticoid Therapy on Mortality in Patients with Rheumatoid Arthritis and Diabetic Mellitus
Mohammad Movahedi and William G Dixon, Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom
Background/Purpose Glucocorticoid (GC) therapy is known to increase the risk of new-onset type 2 diabetes mellitus (DM). Furthermore, GC therapy increases blood glucose in diabetic…
Abstract Number: 2810 • 2014 ACR/ARHP Annual Meeting
Reduced Mortality Risk in Rheumatoid Arthritis: Findings from Two UK Inception Cohorts
Sam Norton¹, Elena Nikiphorou², Lewis Carpenter³, David Walsh^4,5, Patrick Kiely⁶, Josh Dixey⁷ and Adam Young^2,8, ¹Institute of Psychiatry, King's College London, London, United Kingdom, ²School of Life & Medical Sciences, University of Hertfordshire, Hatfield, United Kingdom, ³Centre for Lifespan & Chronic Illness Research, University of Hertfordshire, Hatfield, United Kingdom, ⁴Arthritis Research UK Pain Centre, University of Nottingham, Nottingham, United Kingdom, ⁵Rheumatology, Sherwood Forest Hospitals NHS Foundation Trust, Sutton-in-Ashfield, United Kingdom, ⁶Rheumatology Dept, St. Georges Healthcare NHS Trust, London, United Kingdom, ⁷Rheumatology, New Cross Hospital, Wolverhampton, United Kingdom, ⁸Rheumatology, ERAS, St Albans City Hospital, St Albans, United Kingdom
Background/Purpose Rheumatoid arthritis (RA) is associated with a 20 to 30% increased risk of mortality from all-causes compared to the general population. The aim of…
Abstract Number: 2388 • 2014 ACR/ARHP Annual Meeting
DMARD Use after an Initial Acute MI Is Associated with Reduced Risk of a Recurrent Event and Mortality
Jie Zhang¹, Fenglong Xie², Lang Chen³, Huifeng Yun⁴, Paul M. Muntner⁵, Emily Levitan⁵, Monica Safford⁶, Kenneth G. Saag⁷, Jasvinder A. Singh⁶ and Jeffrey R. Curtis⁶, ¹Ryals Soph Bldg., Rm. 517b, Univ. of Alabama at Birmingham, Birmingham, AL, ²Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ³Medicine, University of Alabama at Birmingham, Birmingham, AL, ⁴Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, ⁵Epidemiology, University of Alabama at Birmingham, Birmingham, AL, ⁶University of Alabama at Birmingham, Birmingham, AL, ⁷Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL
Background/Purpose Previous studies have suggested that disease modifying anti-rheumatic drugs (DMARDs) may reduce cardiovascular risk among patients with rheumatoid arthritis (RA). This analysis examined whether…
Abstract Number: 1770 • 2013 ACR/ARHP Annual Meeting
All-Cause Mortality For Patients with Rheumatoid Arthritis In a Universal Public Health Care System
Jessica Widdifield^1,2, J. Michael Paterson¹, Sasha Bernatsky³, Bindee Kuriya⁴, J. Carter Thorne⁵, Simon Hollands¹ and Claire Bombardier⁶, ¹Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³McGill University, Montreal, QC, Canada, ⁴Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁵Southlake Regional Health Centre, Newmarket, ON, Canada, ⁶Rheumatology, University of Toronto, Toronto, ON, Canada
Background/Purpose: Studies evaluating trends in rheumatoid arthritis (RA) mortality over time have produced inconsistent results. Our aim was to estimate all-cause mortality in RA between…
Abstract Number: 1052 • 2013 ACR/ARHP Annual Meeting
Glucocorticosteroids and Mortality Risk In Rheumatoid Arthritis – Results Of a Population Based Study
Diane Lacaille¹, J. Antonio Avina-Zubieta^2,3, Eric C. Sayre², Michal Abrahamowicz⁴ and John Esdaile^1,5, ¹Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Richmond, BC, Canada, ²Arthritis Research Centre of Canada, Richmond, BC, Canada, ³Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁴Division of Clinical Epidemiology, McGill University, Montreal, QC, Canada, ⁵Medicine, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Glucocorticosteroids (GC) are frequently used in the management of rheumatoid arthritis (RA). Due to their metabolic and immunosuppressive effects, they could increase the risk…
Abstract Number: 779 • 2013 ACR/ARHP Annual Meeting
Low Cardiovascular Mortality Among Early Rheumatoid Arthritis Patients — A Nationwide Register Study 2000—2008
Anne M. Kerola¹, Tuomo Nieminen², Lauri J. Virta³, Hannu Kautiainen⁴, Kari Puolakka⁵, Tuomas Kerola⁶, Timo Pohjolainen⁷ and Markku J. Kauppi⁶, ¹Medical School, University of Helsinki, Helsinki, Finland, ²Division of Cardiology, Helsinki University Central Hospital, Helsinki, Finland, ³Research Department, the Social Insurance Institution, Turku, Finland, ⁴Unit of Primary Health Care, Helsinki University Central Hospital, Helsinki, Finland, ⁵Department of Medicine, South Karelia Central Hospital, Lappeenranta, Finland, ⁶Department of Internal Medicine, Päijät-Häme Central Hospital, Lahti, Finland, ⁷ORTON Rehabilitation Centre, ORTON Foundation, Helsinki, Finland
Background/Purpose: Increased cardiovascular (CV) mortality in established rheumatoid arthritis (RA) is a widely accepted threat, but in early RA or inception cohorts, growing evidence suggests…
Abstract Number: 1642 • 2012 ACR/ARHP Annual Meeting
Biologics and Mortality Risk in Rheumatoid Arthritis – Results of a Population Based Study
Diane Lacaille¹, Michal Abrahamowicz², Eric C. Sayre³ and John Esdaile⁴, ¹Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Richmond, BC, Canada, ²Clinical Epidemiology, McGill University, Montreal, QC, Canada, ³Arthritis Research Centre of Canada, Vancouver, BC, Canada, ⁴Rheumatology, Arthritis Research Centre of Canada, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Biologic agents, due to their effect on disease activity, may reduce the risk of premature mortality in rheumatoid arthritis (RA). We evaluated the association…
Abstract Number: 1245 • 2012 ACR/ARHP Annual Meeting
Age-Specific Association Between Disease-Related Measures and Incident Cardiovascular Events and All-Cause Mortality in Early Rheumatoid Arthritis
Sofia Ajeganova¹, Maria LE Andersson², Johan Frostegård³ and Ingiäld Hafström¹, ¹Karolinska Institutet, Unit of Rheumatology, Department of Medicine Huddinge, Stockholm, Sweden, ²R&D Center, Spenshult Hospital, Oskarström, Sweden, ³Karolinska Institutet, Section of Immunology and chronic disease, Institute of Environmental Medicine, Stockholm, Sweden
Background/Purpose: Increased risk of cardiovascular disease (CVD) and premature mortality in rheumatoid arthritis (RA) has been established, but the impact of inflammatory and disease related…
Abstract Number: 822 • 2012 ACR/ARHP Annual Meeting
Greater Than Expected Increased Mortality Following Fragility Fractures in Women and Men with Rheumatoid Arthritis
Shreyasee Amin¹, Sherine E. Gabriel², Sara J. Achenbach³, Elizabeth J. Atkinson³ and L. Joseph Melton III⁴, ¹Rheumatology and Health Sciences Research, Mayo Clinic, Rochester, MN, ²Health Sciences Research & Div of Rheumatology, Mayo Clinic, Rochester, MN, ³Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Department of Hlth Sciences, Mayo Clinic, Rochester, MN
Background/Purpose: Women and men with RA are at an increased risk for fracture [fx] as well as greater overall mortality. It is recognized that in…
Abstract Number: 767 • 2012 ACR/ARHP Annual Meeting
Patients with Early Inflammatory Arthritis Who Fulfil the 2010 American College Rheumatology/European League Against Rheumatism Classification Criteria for Rheumatoid Arthritis Have Increased Mortality Compared to Those Who Do Not: Results From the Norfolk Arthritis Register
Jh Humphreys¹, Suzanne Verstappen², Mark Lunt³, Jackie Chipping⁴, Kimme Hyrich⁵, Tarnya Marshall⁶ and Deborah Symmons⁷, ¹Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit,, Manchester, United Kingdom, ²Arthritis Research UK Epidemiology Unit,, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, ³Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester, United Kingdom, ⁴Norfolk Arthritis Register, School of Medicine Health Policy and Practice Faculty of Health UEA, Norwich, United Kingdom, ⁵Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, ⁶Rheumatology, Norfolk and Norwich University Hospitals Trust, Norwich, United Kingdom, ⁷Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester Academy of Health Sciences, Manchester, United Kingdom
Background/Purpose: Mortality is increased in rheumatoid arthritis (RA) in comparison with the general population. The majority of studies have used the 1987 ACR criteria to…
Abstract Number: 357 • 2012 ACR/ARHP Annual Meeting
Is the Impact of Methotrexate On Mortality in Rheumatoid Arthritis Independent of Its Effect On Disease Activity?
Dietmar MJ Krause¹, Bernadette Gabriel², Gertraud Herborn³ and Rolf Rau⁴, ¹Internistische und rheumatologische Gemeinschaftspraxis, Gladbeck, Germany, ²Private Practice, Gladbeck, Germany, ³Rheumatology, Evangelisches Fachkrankenhaus, Ratingen, Germany, ⁴Evangelisches Fachkrankenhaus, Ratingen, Germany
Background/Purpose: Methotrexate (MTX) is the anchor drug in the treatment of rheumatoid arthritis (RA). MTX shows effects on disease activity, radiologic progression and mortality. These…
Abstract Number: 87 • 2012 ACR/ARHP Annual Meeting
Prediction of Mortality in Rheumatoid Arthritis Using a Serum Cytokine Profile
Agustin Escalante¹, Roy W. Haas¹, Daniel F. Battafarano² and Inmaculada Del Rincon³, ¹Dept. of Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Medicine / MCHE-MDR, Brooke Army Medical Ctr, San Antonio, TX, ³Rheumatology, University of Texas Health Science Center, San Antonio, TX
Background/Purpose: Cytokines are important in the pathogenesis of RA. Their concentration in the serum rises immediately prior to RA onset, and may be associated with…
Abstract Number: 70 • 2012 ACR/ARHP Annual Meeting
The Impact of Systemic Autoimmune Rheumatic Disease On One-Year Mortality in Congestive Heart Failure Patients: A Population-Level Analysis
Stephanie O. Keeling¹, Asvina Bissonauth¹, Becky Leung² and Padmaja Kaul², ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Cardiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Little is known about the prevalence of systemic autoimmune rheumatic diseases (SARDs) in patients with congestive heart failure (CHF) and its contribution to long-term…

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