ACR Meeting Abstracts

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Abstracts tagged "monocytes"

  • Abstract Number: 1730 • 2013 ACR/ARHP Annual Meeting

    Novel Role For Ly6C– Monocyte Subsets and Joint Macrophages In Mouse Model Of Rheumatoid Arthritis

    Alexander Misharin1, Carla M. Cuda2, Rana Saber3, Angelica K. Gierut4, G. Kenneth Haines III5, Steffen Jung6 and Harris R. Perlman7, 1Medicine, Division of Rheumatology, Northwestern University, Chicago, IL, 2Medicine / Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Medicine/Rheumatology, Northwestern University, Chicago, IL, 4Rheumatology, Northwestern Med Faculty Found, Chicago, IL, 5Department of Pathology, Yale University, New Haven, CT, 6Immunology, Weizmann Institute, Rehovot, Israel, 7Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Monocytes and macrophages play a key role in the pathogenesis of rheumatoid arthritis. However, role of the individual subsets of monocytes and macrophages in…
  • Abstract Number: 1625 • 2013 ACR/ARHP Annual Meeting

    Prolactin-Induced Interferon Regulatory Factor 1 Activation and Histone H4 Hyperacetylation In Monomac-6 Cells Correlating With Changes Seen In Monocytes From Systemic Lupus Erythematosus Patients

    Yiu Tak Leung1, Lihua Shi2, Kelly Maurer2, Li Song2, Michelle Petri3 and Kate Sullivan4, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Immunology ARC 1216, The Children's Hospital of Philadelphia, Philadelphia, PA, 3Johns Hopkins University School of Medicine, Baltimore, MD, 4Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Epigenetic changes have been described in systemic lupus erythematosus (SLE) and offer a potential explanation for the chronicity of disease and missing heritability. Therapies…
  • Abstract Number: 1152 • 2013 ACR/ARHP Annual Meeting

    Ligation Of TLR5 Promotes Myeloid Cell Infiltration and Differentiation Into Mature Osteoclasts In RA Patients and Experimental Arthritis

    Seung-jae Kim1, Zhenlong Chen1, Nathan D. Chamberlain1, Michael V. Volin2, Suncica Volkov1, William Swedler3, Shiva Arami4, Anjali Mehta5, Nadera J. Sweiss6 and Shiva Shahrara1, 1Medicine/Rheumatology, University of Illinois at Chicago, Chicago, IL, 2Department of Microbiology and Immunology, Chicago College of Osteopathic Medicine Midwestern University, Downers Grove, IL, 3Section of Rheumatology, University of Illinois at Chicago, Chicago, IL, 4Medicine - Rheumatology, University of Illinois at Chicago, Chicago, IL, 5University of Illinois at Chicago, Chicago, IL, 6internal medicine section of rheumatology, University of Illinois at Chicago, Chicago, IL

    Background/Purpose: The aim of this study was to examine the importance of TLR5 ligation in the pathogenesis of rheumatoid arthritis (RA) and experimental arthritis. Methods:…
  • Abstract Number: 2616 • 2012 ACR/ARHP Annual Meeting

    The Transition From Psoriasis (Ps) to Psoriatic Arthritis (PsA) Is Associated with Elevated Circulating Osteoclast Precursors (OCP) and Increased Expression of DC-STAMP

    Ya-Hui Chiu1, Edward M. Schwarz2, Dafna D. Gladman3, Sharon Moorehead4, Michelle Smith4, Rick Barrett4 and Christopher T. Ritchlin4, 1Allergy, Immunology, and Rheumatology, University of Rochester, Rochester, NY, 2Center for Musculoskeletal Research, University of Rochester, Rochester, NY, 3Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, 4Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY

    Background/Purpose: Approximately 20% of psoriasis (Ps) patients (pts) develop psoriatic arthritis (PsA). Early diagnosis and therapy of PsA can limit bone and joint damage; however,…
  • Abstract Number: 1783 • 2012 ACR/ARHP Annual Meeting

    TNFα Influences RasGRP1 and RasGRP3 Expression Levels in PBMC, B and T Cells

    Marie-Laure Potier1, Martine Hiron1, Clément Guillou1, Céline Derambure2, Olivier Boyer3, Xavier Le Loët4, Olivier Vittecoq5 and Thierry Lequerré6, 1Inserm 905 & Institute for Biomedical Research, University of Rouen, Rouen, France, 2Inserm 905 & Institute for Biomedical Research, University of Rouen, Rouen, France, Rouen, France, 3Immunology, Inserm 905, Institute for Biomedical research, University of Rouen, Rouen, France, 4Rheumatology Department, Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen Cedex, France, 5Rheumatology, Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen Cedex, France, 6Rheumatology Department & Inserm 905, Department of Rheumatology, Rouen University Hospital & Inserm 905, Institute for Biomedical Research, University of Rouen, Rouen Cedex, France

    Background/Purpose: Rheumatoid arthritis (RA) is the most common inflammatory arthritis. B and T lymphocytes play a central role in the pathophysiology of RA. RasGRP is…
  • Abstract Number: 1476 • 2012 ACR/ARHP Annual Meeting

    Caveolin-1 Deficiency May Play a Role in the Predisposition of African Americans to SSc ILD

    Elena Tourkina1, Charles Reese1, Beth Perry2, Shanice Dyer1, Michael Bonner3, Richard P. Visconti4, Jing Zhang5, Richard M. Silver1 and Stanley Hoffman2, 1Rheumatology, Medical University of SC, Charleston, SC, 2Rheumatology, Medical University of South Carolina, Charleston, SC, 3Division of Rheumatology, Medical University of South Carolina, Charleston, SC, 4Cell Biology and Regenerative Medicine, Medical University of South Carolina, Charleston, SC, 5Cell Biology and Anatomy, Medical University of SC, Charleston, SC

    Background/Purpose: Scleroderma-associated Interstitial Lung Disease (SSc-ILD) is more prevalent and more severe in African Americans (AA) than in Caucasian (C) patients, but little is known…
  • Abstract Number: 1073 • 2012 ACR/ARHP Annual Meeting

    Increased Oxidative Burst in Neutrophils but Not Monocytes in Systemic Lupus Erythematosus

    Sandro F. Perazzio1, Reinaldo Salomao2, Neusa P. Silva3 and Luis Eduardo C. Andrade4, 1Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Infectology, Federal University of Sao Paulo, Sao Paulo, Brazil, 3Rheumatology Div/Dept of Med, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 4Rheumatology Division, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

    Background/Purpose: The role of innate immunity in the pathogenesis of Systemic Lupus Erythematosus (SLE) has acquired increasing importance lately. Chronic Granulomatosus Disease (CGD), a hereditary…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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