Abstracts tagged "monocytes and scleroderma"

Abstract Number: 1709 • ACR/ARHP Annual Meeting 2017
Classical Monocytes in the Pathogenesis of Early Diffuse Cutaneous Systemic Sclerosis
Julia Dunn¹, Salina Dominguez¹, Philip J. Homan¹, Carla Cuda¹, Dinesh Khanna², Shervin Assassi³, Tracy M. Frech⁴, Harris Perlman⁵, Deborah R. WInter¹ and Monique Hinchcliff⁶, ¹Department of Medicine Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²University of Michigan, Ann Arbor, MI, ³University of Texas McGovern Medical School, Houston, TX, ⁴Division of Rheumatology, University of Utah, Salt Lake City, UT, ⁵Department of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Northwestern University Feinberg School of Medicine,, Chicago, IL, ⁶Northwestern University Institute for Public Health and Medicine, Chicago, IL
Background/Purpose: In light of heterogeneous clinical manifestations in systemic sclerosis (SSc), transcriptional analysis of fibrotic tissue and circulating leukocytes may illuminate conserved processes driving inflammation…