Abstracts tagged "monocytes and osteoclasts"

Abstract Number: 459 • 2016 ACR/ARHP Annual Meeting
Resident Non-Classical Monocytes Are Critically Important for Tissue Destruction in Arthritis
Antonia Puchner¹, Victoria Saferding², Michael Bonelli³, Carl-Walter Steiner², Eliana Goncalves-Alves³, Silvia Hayer⁴, Yohei Mikami⁵, Marije M. Koenders⁶, Birgit Niederreiter⁷, Josef S. Smolen⁸, Kurt Redlich³, Stephan Blüml⁹ and Michael Bonelli and Stephan blueml, ¹Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Rheumatology, Medical University of Vienna, Vienna, Austria, ³Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Waehringer Guertel 18-20 A-A09, Medical University of Vienna, Vienna, Austria, ⁵Molecular Immunology and Inflammation Branch, NIAMS, Bethesda, MD, ⁶Rheumatology Research and Advanced Therapeutics, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands, ⁷Rheumatology, Internal Medicine III, Medical University of Vienna, Vienna, Austria, ⁸Medical University of Vienna, Vienna, Austria, ⁹Internal Medicine 3; Division of Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: Bone destruction in rheumatoid arthritis is mediated by osteoclasts, which are derived from precursor cells of the myeloid lineage. Although there is much known…

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