ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "monoclonal antibodies and randomized trials"

  • Abstract Number: 3223 • 2015 ACR/ARHP Annual Meeting

    Anifrolumab, an Anti-Interferon Alpha Receptor Monoclonal Antibody, in Moderate to Severe Systemic Lupus Erythematosus (SLE)

    Richard Furie1, JT Merrill2, VP Werth3,4, M Khamashta5, K Kalunian6, P Brohawn7, G Illei7, J Drappa7, L Wang7 and S Yoo8, 1North Shore-LIJ Health System, New York, NY, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Philadelphia V.A. Medical Center, Philidelphia, PA, 4University of Pennsylvania, Philadelphia, PA, 5Graham Hughes Lupus Research Laboratory, The Rayne Institute, St Thomas' Hospital, London, United Kingdom, 6UCSD School of Medicine, La Jolla, CA, 7MedImmune, Gaithersburg, MD, 8Regenx Bio, Rockville, MD

    Background/Purpose: The efficacy and safety of anifrolumab (ANIFR), a type I IFN receptor antagonist, were assessed in a Phase II, randomized, double-blind, placebo-controlled study in…
  • Abstract Number: 721 • 2015 ACR/ARHP Annual Meeting

    Geographic Differences in Demographics, Clinical Characteristics, and Standard of Care in Multinational Studies of Patients with Moderate to Severe Systemic Lupus Erythematosus

    Richard Furie1, M Khamashta2, L Wang3, J Drappa3, W Greth3 and G Illei3, 1Division of Rheumatology, North Shore - LIJ Health System, New York, NY, 2Graham Hughes Lupus Research Laboratory, The Rayne Institute, St Thomas' Hospital, London, United Kingdom, 3MedImmune, Gaithersburg, MD

    Background/Purpose: Most randomized controlled trials (RCTs) in systemic lupus erythematosus (SLE) include stratification factors to ensure a balanced allocation of subgroups that might respond differently…
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ACR Pediatric Rheumatology Symposium 2020

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