Abstracts tagged "monoclonal antibodies and osteoarthritis"

Abstract Number: 2006 • 2015 ACR/ARHP Annual Meeting
Effect Size of the Anti-Aggrecanase-2 Monoclonal Antibody CRB0017 in Rodent Models of Osteoarthritis
Gianfranco Caselli¹, Riccardo Chiusaroli², Michela Visintin³, Marco Lanza², Flora Ferrari², Dario Tremolada², Beatrice Barbetta², Giampaolo Giacovelli², Albino Bonazzi² and Lucio Claudio Rovati², ¹Pharmacology & Toxicology, Rottapharm Biotech Srl, Monza, Italy, ²Rottapharm Biotech Srl, Monza, Italy, ³Rottapharm Biotech Srl, Trieste, Italy
Background/Purpose : There is huge interest in the family of “A Disintegrin And Metalloproteinase with ThromboSpondin motifs” (ADAMTS) proteinases, especially aggrecanase-2 (ADAMTS-5), as therapeutic targets…

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Abstracts tagged "monoclonal antibodies and osteoarthritis"

Effect Size of the Anti-Aggrecanase-2 Monoclonal Antibody CRB0017 in Rodent Models of Osteoarthritis