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Abstracts tagged "molecular mimicry"

  • Abstract Number: 531 • ACR/ARHP Annual Meeting 2015

    Immune Responses to Mycobacterium Heat Shock Protein 70 Accompany Self-Reactivity to Human Bip in Rheumatoid Arthritis

    Hirofumi Shoda1, Shuji Sumitomo1, Keishi Fujio2 and Kazuhiko Yamamoto1, 1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, 2Department of Allergy and Rheumatology,Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

    Background/Purpose: Molecular mimicry is believed to be an important mechanism of autoimmunity development. We previously demonstrated that imbalance between effector and regulatory T cells specific for BiP, a…

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