Abstracts tagged "mitochondria and synovium"

Abstract Number: 966 • 2017 ACR/ARHP Annual Meeting
In Search of Mechanisms Underlying Fibroblast-like Synoviocyte Cell-to-Cell Cargo Transfer
Ruth Byrne¹, Isabel Olmos Calvo², Felix Kartnig³, Uwe Hansen⁴, Denise Beckmann⁴, Adelheid Korb-Pap⁴, Bernhard Brandstätter¹, Thomas Karonitsch¹, Günter Steiner¹, Johannes Holinka⁵, Peter Ertl⁶, Thomas Pap⁴, Josef S. Smolen⁷ and Hans Peter Kiener¹, ¹Rheumatology, Medical University of Vienna, Vienna, Austria, ²Department of Chemical Technologies and Analytics, Vienna University of Technology, Vienna, Austria, ³CeMM, Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria, ⁴Institute of Musculoskeletal Medicine, University Hospital Muenster, Muenster, Germany, ⁵Orthopaedics, Medical University of Vienna, Vienna, Austria, ⁶Vienna University of Technology, Vienna, Austria, ⁷Medical University Vienna, Division of Rheumatology, Department of Internal Medicine III, Vienna, Austria
Background/Purpose: The synovium is primarily built by fibroblast-like-synoviocytes (FLS). These cells form a complex tissue network via long-distance connections (nanotubes) and wide intercellular matrix spaces.…
Abstract Number: 2157 • 2016 ACR/ARHP Annual Meeting
Share the Fate: Fibroblast-like Synoviocyte Cell-to-Cell Organelle Transfer Is Directed By the Inflammatory Microenvironment
Ruth Byrne¹, Isabel Olmos Calvo², Thomas Karonitsch³, Felix Kartnig⁴, Johannes Holinka⁵, Günter Steiner⁶, Peter Ertl⁷, Josef Smolen⁸ and Hans Peter Kiener⁹, ¹Rheumatology, Internal Medicine III, Medical University of Vienna, Vienna, Austria, ²Nanotechnology, Austrian Institute for Technology, Vienna, Austria, ³Internal Medicine III, Vienna Medical University, Vienna, Austria, ⁴Department of Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁵Department of Orthopaedics, Medical University of Vienna, Vienna, Austria, ⁶Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁷Vienna University of Technology, Vienna, Austria, ⁸Medical University of Vienna and Hietzing Hospital, Vienna, Austria, ⁹Division of Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: Fibroblast-like synoviocytes (FLS) form a complex tissue network via long-distance intercellular connections with wide intercellular matrix spaces. The adaptive synovial tissue response to inflammation…

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